thesis company nootropics

We’re independently supported by our readers and we may earn a commission when you buy through our links.

What are you looking for?

Search ideas for you, thesis nootropics review.

Sheridan Grant

Content Specialist

Sheridan is a writer from Hamilton, Ontario. She has a passion for writing about what she loves and learning new things along the way. Her topics of expertise include skincare and beauty, home decor, and DIYing.

Table of Contents

About Thesis Nootropics

Hands up if you guzzle five coffees a day to stay awake, have tried all the supplements in the book desperate to improve your headspace, and aren’t interested in prescribed medications. Designed to increase focus , Thesis nootropics might be for you. 

Thesis offers a customized blend of ingredients designed to optimize your cognitive function , with personalized details that tackle your specific needs. Nootropics boost brain performance in the same way a stimulant would, without the common negative effects. 

A study published in the Journal of Alzheimer’s Disease found that nootropics may help improve cognitive function in people with Alzheimer’s disease.

Interested in finding out more about the brand and how it works? Leaf through our Thesis Nootropics review. We’ll be your guide through the company and the process, as well as details on the treatments, highlights from customer reviews, answers to important FAQs, and more, to help you decide if it’s worth the try.

Pros and Cons

• Multiple cognitive benefits: Thesis Nootropics offers a variety of blends that cater to multiple aspects of cognitive function.
• Long-term effects: On top of short term benefits for daily life, Thesis nootropics ingredients are designed to impact the brain in the long-term.
• Personalized recommendations: Thesis Nootropics makes personalized recommendations based on your goals and unique brain chemistry.
• Potential side effects: The most common side effects to watch out for when you start taking Thesis Nootropics include heartburn, headaches, confusion, dizziness, loss of appetite, and digestive issues.
• Need to stop taking if issues arise: If you experience a headache or an upset stomach that won’t go away while taking their nootropics, Thesis recommends that you stop taking them.

What is Thesis Nootropics?

Nootropics are nutrient compounds and substances that are known to improve brain performance , such as caffeine and creatine. They help with issues that affect motivation, creativity, mood, memory, focus, and cognitive processing.

Nootropics are the ideal addition to an already healthy lifestyle that consists of exercise, proper nutrition, and enjoyable activities.  Thesis nootropics are carefully formulated to target specific needs, ranging from energy to creativity. The brand focuses on safety, ensuring that all supplements adhere to FDA guidelines and go through multiple clinical trials. 

How Thesis Nootropics Works

With all that being said, you may be wondering how Thesis provides users with an option that is specific to their needs. Fortunately, the process is simple and hassle free. Here’s how it works:

• Take the Thesis nootropics quiz
• Answer questions about your basic information
• Receive personalized recommendations 
• Get your starter kit for $120 , or $79 monthly when you subscribe 

After that, you’ll select one formula to take each week, taking one day off in between each different option. You’ll also track your results in the daily journal over the month to see how they affect your daily life. 

From there, it operates as a subscription service. Users will be able to optimize their next shipment by telling the brand which formulas worked best.

If you don’t like any of the blends in your box, let the company know and they’ll switch it for something that’s a better fit for your lifestyle, genetics, and goals.

Thesis Nootropics Ingredients

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties. Here are some of the key ingredients in Thesis Nootropics:

• Cognizin (Citicoline) : Cognizin is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• L-Theanine : L-Theanine is an amino acid that is found in green tea, and is known for its ability to promote relaxation and reduce stress and anxiety.
• Lion’s Mane Mushroom : Lion’s Mane Mushroom is a type of medicinal mushroom that is believed to have cognitive-boosting properties, including improved memory and focus.
• Rhodiola Rosea : Rhodiola Rosea is an adaptogenic herb that is known for its ability to reduce stress and fatigue, and improve mental clarity and cognitive function.
• Ashwagandha : Ashwagandha is an adaptogenic herb that is known for its ability to reduce stress and anxiety, and improve memory and cognitive function.
• Phosphatidylserine : Phosphatidylserine is a type of phospholipid that is found in high concentrations in the brain, and is believed to support cognitive function, including memory and focus³
• Alpha-GPC : Alpha-GPC is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• TAU (uridine): TAU is a blend of uridine, choline, and DHA, which is believed to support brain health and cognitive function.
• Artichoke extract : Artichoke extract is believed to enhance cognitive function by increasing levels of acetylcholine, a neurotransmitter that is important for memory and learning.
• Dynamine : Dynamine is a type of alkaloid that is believed to enhance cognitive function by increasing levels of dopamine, a neurotransmitter that is important for mood and motivation.

Overall, the ingredients in Thesis Nootropics are carefully chosen for their cognitive-boosting properties, and are designed to work together to enhance overall brain health and cognitive function.

Thesis Nootropics Health Benefits

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties, and offer numerous health benefits. Here are some of the health benefits of Thesis Nootropics:

• Increased cognitive energy : One of the key benefits of Thesis Nootropics is increased cognitive energy, which can help improve productivity, mental alertness, and motivation, as it contains cognizin .
• Enhanced mental clarity : Another benefit of Thesis Nootropics is enhanced mental clarity,given from Lion’s Mane Mushroom which can help reduce brain fog and improve focus.
• Improved memory and learning abilities : Thesis Nootropics contains ingredients that are believed to improve memory and learning abilities, like Phosphatidylserine , which can help users retain information more effectively.
• Elevated mood : Thesis Nootropics may help elevate mood and reduce symptoms of anxiety and depression, thanks to ingredients like L-Theanine and Ashwagandha .
• Lowered stress levels : The adaptogenic herbs in Thesis Nootropics, such as Rhodiola Rosea and Ashwagandha , are known for their ability to lower stress levels and promote relaxation.
• Boosted focus : Thesis Nootropics contains ingredients like Alpha-GPC and Artichoke extract , which are believed to boost focus and concentration.

While Thesis Nootropics offers numerous health benefits, it’s important to note that the long-term effects of nootropics are not yet fully understood and more research is needed.

3 Thesis Nootropics Bestsellers

Thesis energy review.

If you’re constantly struggling to keep up with the demands of your busy life, it might be time to try a natural energy booster like Thesis Energy. This powerful nootropic blend is specifically designed to increase energy, overcome fatigue, and build mental stamina.

Thesis Energy is caffeine-free, making it a great option for those who are sensitive to caffeine or looking for a natural alternative to traditional energy drinks. The Energy formulation is designed to help improve focus and mental clarity, increase cognitive energy, and reduce fatigue. Whether you’re facing a busy day at work, recovering after a night of poor sleep, or gearing up for an intense workout, Thesis Energy can help you power through.

Each ingredient in Thesis Energy is carefully chosen for its energy-boosting properties. The specific ingredients can vary depending on your needs, but they work together to help increase energy, improve mental clarity, and reduce fatigue.

To get the most out of Thesis Energy, take it every morning on an empty stomach. You can also take it again after lunch if you need an extra boost. It’s designed to help you tackle busy, hectic days, recover from poor sleep, and power through intense workouts.

If you’re tired of relying on coffee and energy drinks to get through the day, it might be time to give Thesis Energy a try. Check availability and start boosting your energy naturally today!

Thesis Creativity

If you’re someone who struggles with creativity or finds yourself feeling stuck in your creative endeavors, Thesis Creativity may be worth considering. This nootropic supplement is designed to help spark inspiration, enhance verbal fluency, and boost confidence in your own great ideas.

So what’s in Thesis Creativity? The ingredients may vary depending on your specific needs, but these ingredients work together to support stress management, memory function, mood regulation, and energy production.

By supporting stress management, memory function, and mood regulation, Thesis Creativity can help free up mental space for more creative thinking. Additionally, the caffeine and L-theanine combo can provide a boost of energy and focus without the jitters and crash that can come with caffeine alone.

To get the most out of Thesis Creativity, it is recommended to take it every morning on an empty stomach and again after lunch if you need an extra boost. This nootropic blend is particularly helpful for brainstorming and creative thinking, writing and creative projects, and public speaking and social situations.

As with any nootropic supplement, it’s important to note that the long-term effects of Thesis Creativity are not yet fully understood and more research is needed. It’s always a good idea to speak with a healthcare professional before adding any new supplements to your routine.

In summary, if you’re looking for a little extra help in the creativity department, Thesis Creativity may be a valuable addition to your nootropic lineup. Its unique blend of ingredients can help support mental clarity, mood regulation, and energy production, making it a valuable tool for any creative individual.

Thesis Logic

If you’ve been having trouble with your memory lately, such as forgetting what you had for lunch yesterday or struggling to recall common words, then Thesis Logic may be just what you need. This formula is designed to help enhance your processing speed, boost your memory, and deepen your thinking.

Thesis Logic is caffeine-free, making it a great option for those who are sensitive to caffeine. The formula is ideal for use during deep, focused work, complex problem-solving, research projects, and completing tedious tasks.

Taking Thesis Logic is easy – simply take it every morning on an empty stomach, and take it again after lunch if you need an extra boost. By incorporating Thesis Logic into your daily routine, you may notice improvements in your cognitive function and overall mental performance.

Who Is Thesis Nootropics For? 

Thesis nootropics are designed for a number of different specific needs, including anyone who wants to focus better, have more energy, and maintain mental clarity. All in all, the products are specifically formulated to improve day to day life and target your specific needs .

Thesis Nootropics Side Effects

While Thesis nootropics are designed to enhance cognitive performance and provide a range of benefits, it’s important to be aware of the potential side effects that can occur. As with any supplement, individual reactions can vary, and some people may experience side effects while others may not.

Some of the potential side effects of Thesis nootropics include:

• Insomnia : Some nootropics contain caffeine or other stimulants that can disrupt sleep patterns and lead to difficulty falling asleep or staying asleep.
• Blurry vision : Certain nootropics, such as those containing alpha GPC, have been linked to temporary blurry vision.
• High blood pressure : Stimulant-based nootropics can increase blood pressure, which can be dangerous for people with hypertension or other heart conditions.
• Fast heart rate : Similarly, stimulants can also increase heart rate, leading to palpitations or a rapid pulse.
• Circulation problem s: Certain nootropics, such as vinpocetine, can affect blood flow and circulation, leading to issues like dizziness, nausea, or headaches.
• Addiction : Some nootropics, such as those containing racetams, have been associated with the potential for addiction or dependence if used long-term.

It’s important to remember that not all nootropics will produce these side effects, and the severity of any reactions will depend on individual factors such as dosage, duration of use, and underlying health conditions. However, it’s always wise to discuss any potential risks with a healthcare professional before starting any new supplement regimen.

Additionally, it’s important to follow dosage instructions carefully and not to exceed recommended amounts, as this can increase the risk of side effects. By being mindful of potential risks and using nootropics responsibly, users can reap the benefits of these supplements without experiencing adverse effects.

Thesis Nootropics Reviews: What Do Customers Think?

At this point in our Thesis nootropics review, it’s time to turn to what customers are saying. So, we sourced testimonials from the brand’s website, Reddit, and ZenMasterWellness. And spoiler alert, the Thesis nootropics reviews we came across have nothing but good things to say.

On takethesis.com , the brand earns 4.4/5 stars out of 7,956 reviews. One patron describes their particular blend as the perfect alternative to prescription meds :

“ I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work .”

On Reddit, many reviewers share similar sentiments about how effective the products are. One buyer shares that they tried tons of different nootropics on the market, and Thesis stands out amongst the crowd . 

On ZenMasterWellness, one reviewer states that their blend provided the exact results they were looking for :

“ They offer notable improvements to how well I’m able to focus, stay on task, and grind when it’s time to grind. In practice, this usually looks like a clearer mind and an improved ability to just… chill. With the Clarity and Creativity blends, in particular, I just feel leveled out .”

Backed by clinical trials and real customer experiences, Thesis stands out in the world of nootropics and supplements. The personalized selections prove effective, while the quality ingredients live up to expectations. 

Is Thesis Nootropics Legit?

If you’re wondering if this brand offers products that are too good to be true, this Thesis nootropics review is here to say that it is the real deal .

The brand is backed by numerous clinical trials, which highlight how 86% of customers reported improvements in a wide range of cognitive challenges, while 89% noticed an improvement in their ability to reduce stress and maintain energy.

Is Thesis Nootropics Worth It?

Thesis is an appealing choice in the world of nootropics because it provides a completely customized selection based on your needs and goals. Plus, the ingredients are potent and ensure the best effects—and you only end up paying for the benefits you actually need.

With that in mind, this Thesis nootropics review deems the brand worth the try.

Alternatives

Here are some alternatives to Thesis Nootropics that you might find interesting:

• Mind Lab Pro – This nootropic supplement is designed to improve cognitive function and mental performance. It contains 11 ingredients that work together to enhance memory, focus, and overall brain health.
• Thorne Supplements : If you’re looking for high-quality, science-based supplements, Thorne is a great choice. Their products are designed with the latest research in mind and are rigorously tested for quality and purity. Some of their popular offerings include multivitamins, protein powders, and omega-3 supplements.
• WeAreFeel Supplements : WeAreFeel is a supplement brand that offers a variety of products designed to support different aspects of your health. Their supplements are vegan-friendly and free from artificial colors, flavors, and preservatives. Some of their popular offerings include multivitamins, probiotics, and omega-3 supplements.
• Neuro Gum : If you’re looking for a quick and easy way to boost your focus and energy levels, Neuro Gum is a great option. This gum is infused with caffeine and other natural ingredients that can help improve mental clarity and alertness. Plus, it’s sugar-free and comes in a variety of delicious flavors.
• Neuriva Plus : Neuriva Plus is a brain supplement that’s designed to improve memory, focus, and cognitive performance. It contains a blend of natural ingredients, including coffee fruit extract and phosphatidylserine, that have been shown to support brain health. If you’re looking for a natural way to boost your cognitive function, Neuriva Plus is worth considering.

Thesis Nootropics Promotions & Discounts 

There aren’t currently any Thesis promos or discounts available. That being said, if you subscribe for recurring shipments of your recommended products, you’ll save $40 monthly .

Where to Buy Thesis Nootropics

At the time of this Thesis nootropics review, the products are exclusively available on the brand’s website, takethesis.com .

Is Thesis Nootropics vegan?  

Thesis nootropics are made with only vegan ingredients . That being said, while the brand has taken precautions to protect against cross contamination, the products are not certified vegan.

Is Thesis Nootropics gluten-free? 

On top of being vegan, Thesis products are made without gluten, eggs, or nuts . Again, while the brand strives to protect users against cross contamination, the products are not certified gluten free. 

What is Thesis Nootropics’ Shipping Policy?

If you’re anxiously awaiting your order from this Thesis nootropics review, you’ll be happy to hear that the company offers speedy shipping, sending orders out within 1 business day. After that, packages should arrive within only 1-3 business days . Costs are calculated at checkout.

At this time, Thesis is not able to offer international shipping. This Thesis nootropics review recommends following the brand on social media and signing up for the newsletter to stay up to date with shipping policies. 

What is Thesis Nootropics’ Return Policy?

If you find that your Thesis formula isn’t working out, the company requests that you contact them to make changes and adjustments to ensure you are able to receive the proper help.

If you would still like to make a return, follow these simple steps for a refund:

• Submit your refund request
• Ship the items back within 30 days of the original delivery
• Send an email with your tracking number to the brand
• Return any remaining product in their original packaging to: 

Thesis Returns 902 Broadway

6th Floor New York, NY 

Once your return has been received, a refund will be processed and email confirmation will be sent. It’s also important to note that the brand can only refund one month’s supply per customer and return shipping is the customer’s responsibility. 

How to Contact Thesis Nootropics

We hope you enjoyed this Thesis nootropics review! If you have any further questions about the brand or its products, you can contact them using the following methods:

• Call 1 (646) 647-3599
• Email [email protected]

902 Broadway Floor 6 New York, NY 10010

If you’re looking for other ways to boost your productivity via supplements, check out these other brands we’ve reviewed:

Thorne Supplements Review

WeAreFeel Supplements Review

Neuro Gum Review

Neuriva Plus Review

Our team is dedicated to finding and telling you more about the web’s best products. If you purchase through our links, we may receive a commission. Our editorial team is independent.

Ask the community or leave a comment

Customer reviews, leave a review, ask the community or leave a comment cancel reply.

Your email address will not be published. Required fields are marked *

This field is required

This field is required Please use a valid email

Save my name, email, and website in this browser for the next time I comment.

You may also be interested in

As someone who pours herself a tall glass of iced coffee three times a day — and sometimes even more, oops — I figured it wouldn’t hurt to look into other ways to boost my energy and focus. Of course, I also try to get enough sleep, water, and exercise, too. But I was also down to try a few supplements from Thesis, a nootropics company that aims to make you feel more productive with its plant-based blends.

If you’re not familiar, nootropics are similar to adaptogens in that they’re a class of functional plants that are buzzy in the wellness world. But nootropics — which include ingredients like ashwagandha , L-theanine , choline , and functional mushrooms — are more focused on activating different parts of your brain to support motivation, mood, memory, and cognitive processing . That’s why they’re sometimes called smart drugs or cognitive enhancers — and thus have a different role to play than everyday vitamins.

At Thesis, you’re hooked up with a kit of personalized vitamins , adaptogens , and nootropics that are meant to help support you in accomplishing your goals and feeling more energized and productive. I tried them out for a month and I have some thoughts. Here’s what it was like to try Thesis, in case you’re also a coffee fiend who could use a little more focus and energy.

• Price: $79/monthly subscription
• Best for: Energy, focus
• My rating: 4/5
• What we like: Personalized supplements, supportive coaches
• What we don't like: Can seem pricey, you have to be ready for some trial and error

What Is Thesis?

To get started, you’ll first take a quiz on the Thesis website that asks you about how you feel on a day-to-day basis, how much coffee you drink, what your energy levels are like, and how much you sleep (among other lifestyle questions) so that it can determine the best supplements for you. It’ll then send you a starter kit with six different supplement blends targeted for each issue you might be experiencing. From there, it’s up to you to decide which ones you want to continue using. It works like a process of elimination — you experiment by taking each supplement for six days to see whether or not it feels effective.

The Thesis line features eight different supplement blends: Creativity, Focus, Motivation, Clarity, Energy, Motivation, Confidence, and Logic. Though the brand notes it would love to formulate one pill that works for everyone, brain chemistry is so complex, so it decided it’s better to take the long route and have customers try multiple supplements in order to find the best fit for their noggin. That’s why Thesis also puts you in contact with a wellness coach, so you can chat and ask questions with an expert along the way.

How Do Nootropics Work?

Nootropics are meant to allow your brain to do its thing, only faster and with more efficiency. So, instead of slogging away at your desk with brain fog , you might notice that you feel perkier, extra organized, and more on-point than you normally do as you continue taking the supplements.

Some of the blends contain the nootropic acetylcholine , which is a neurotransmitter from the essential nutrient choline known for memory, learning, and healthy brain function . There are also plenty of amino acids, vitamins, and plant-based adaptogens in each packet to fight off fatigue and stress while protecting your brain from toxins so it’s easier to take in info — and actually remember what you learned. Other staple nootropics include ginkgo biloba , certain kinds of mushrooms, and caffeine, each of which plays a unique function in your cognitive function.

My Experience

When I took the Thesis quiz , I said that I wanted to improve my energy, focus, and mood. A few days later, I received my starter kit, which contained Clarity , Confidence , Motivation , and Logic all laid out in cute little boxes. You’re supposed to pick one — each box contains six sachets full of pills — and take a packet a day for six days. I was immediately drawn to Clarity, a supplement combo that’s supposed to help with high-pressure situations, concentration, and tasks that require focus and attention. It has Lion’s Mane extract (a mushroom), caffeine, L-theanine , and a few other ingredients meant to support a calm, focused flow. The idea is to take the supplements in the morning so they kick in before you start your day, and most of the effects are said to last from four to six hours.

I’d been taking Clarity for a few days when I had a phone call with Cindy Yan , a Thesis wellness coach and nootropics expert. We chatted about my usual routine, how I’d been feeling, and any questions I had about the process. When I said I felt a slight uptick in focus, but nothing too dramatic, Yan told me the first couple days are called the “loading phase” which is when the nutrients work their way into your body. If you don’t feel anything after that point, it’s a sign the supplement isn’t necessary or right for your neurochemistry. If you do like how you feel, it’s a keeper.

As we chatted about my routine, Yan realized I’d benefit from Creativity, an ashwagandha-based supplement meant for brainstorming and public speaking, so that I could feel like a rockstar at work. I also told her that I tend to crave a nap around 3 p.m., so she suggested the Energy supplement made with choline and mango leaf extract , which you can take every day or on extra-busy days, before a workout , or whenever you want to feel alert.

Talking to a coach as I tested the supplements was a true perk. While the quiz got me started with some great options, having access to Yan helped me hone in on what I truly needed.

Yan suggested I log how I felt every day as I took each supplement so I could keep track of any noticeable differences. A week in, I looked at the scribbles in my notebook and noticed that I did seem more productive during the six days I took Clarity. I wasn’t launching rockets to the moon, but I was getting through my emails and typing away like a woman on fire.

The next supplement on my agenda was Energy, a blend meant for busy days, intense workouts, and staying alert thanks to its mango leaf, theacrine , caffeine, and n-acetyl cysteine — and this is the one that gave me the most benefit. Yan was right on the money. She said I could take it in the morning and/or right after lunch to nip my afternoon slump in the bud, and it truly worked — no fourth mid-day coffee for me.

The more I took Energy, the less I felt like I needed to unhinge my jaw and dump as much cold brew into my face as possible. I found myself drinking a sensible cup or two in the morning, and that was that. Thesis says you can feel the effects of the supplements in as little as 30 minutes or it can take up to five days for all the benefits to sink in as your body and brain adjust. For me, though, Energy kicked in pretty quickly.

The Bottom Line

Typically, Thesis users land on two or three supplements for their regimen. After the month-long trial phase, you can order just the ones you want and forget about the rest. Personally, I’m sold on Energy and can see myself hanging onto Clarity, too.

Thesis seems to have figured things out in the nootropic supplement realm. While the boxes seem pricey, it isn’t so bad when you think about buying each supplement on your own individually — and the fact that you get a wellness coach, too.

TL;DR: I’d recommend it for anyone who feels fatigued, unproductive, or unfocused, or for folks who rely on caffeine to get through the day, like me. You might just find that there’s a better way.

Studies referenced:

Baba, Y. (2021). Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study. J Med Food. doi: 10.1089/jmf.2020.4803. Epub 2021 Mar 22.

Coqueiro, AY. (2019). Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition. Nutrients. doi: 10.3390/nu11040863.

Gelabert-Rebato, M. (2019). A Single Dose of The Mango Leaf Extract Zynamite ® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Nutrients. 2019 Oct 28;11(11):2592. doi: 10.3390/nu11112592.

Lai, PL. (2013). Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. doi: 10.1615/intjmedmushr.v15.i6.30.

Malík, M, Tlustoš P. Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs. Nutrients. 2022 Aug 17;14(16):3367. doi: 10.3390/nu14163367. PMID: 36014874; PMCID: PMC9415189.

Mokhtari, V. (2017). A Review on Various Uses of N-Acetyl Cysteine. Cell J. doi: 10.22074/cellj.2016.4872.

Penry, JT. (2008). Choline: an important micronutrient for maximal endurance-exercise performance? Int J Sport Nutr Exerc Metab. doi: 10.1123/ijsnem.18.2.191.

Sam, C. (2022). Physiology, Acetylcholine. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32491757.

Silberstein, R. B. (2010). Examining Brain-Cognition Effects of Ginkgo Biloba Extract: Brain Activation in the Left Temporal and Left Prefrontal Cortex in an Object Working Memory Task. Evidence-based Complementary and Alternative Medicine : ECAM , 2011 . https://doi.org/10.1155/2011/164139

Suliman, NA. (2016). Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic. Evid Based Complement Alternat Med. doi: 10.1155/2016/4391375.

Todorova, V. (2021). Plant Adaptogens-History and Future Perspectives. Nutrients. doi: 10.3390/nu13082861.

Wiedeman, AM. (2018). Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. doi: 10.3390/nu10101513.

I Tried 4 Thesis Nootropic Blends (My 2024 Review)

Focus Factor vs. Prevagen (I Tried Both): Who Wins In 2024?

Mind Lab Pro vs. Prevagen (I Tried Both): Who Wins In 2024?

Alpha Brain vs. Prevagen (I Tried Both): Who Wins In 2024?

I Took Prevagen For 30 Days (My 2024 Review)

NooCube vs. Prevagen (I Tried Both): Who Wins In 2024?

Best Nootropics For Athletic Performance (2024)

Qualia Mind vs. Alpha Brain (I Tried Both): Who Wins In 2024?

Qualia Mind vs. NooCube (I Tried Both): Who Wins In 2024?

Mind Lab Pro vs. Qualia Mind (I Tried Both): Who Wins In 2024?

Qualia Mind Works (My 2024 Review)

Thesis stands out in the wellness industry with its personalized nootropic supplements, designed to cater to the individual’s specific cognitive needs. It has been pushed by health and wellness celebrities, causing a wave of popularity.

Do Thesis nootropics live up to the hype?

• Variety Of Blends: Various nootropic blends based on individual brain chemistry, maximizing effectiveness for each user.
• Strong Advocacy and Support: Gained endorsements from notable wellness advocates and public figures, like Andrew Huberman, enhancing credibility.
• Limited Clinical Research: While the company plans clinical trials, the current scientific backing may be limited.
• Price: The ongoing cost of customized nootropics may be higher than standard off-the-shelf supplements or medications.
• Dependence on Self-Reporting: The effectiveness of blends relies partly on user feedback, which may not always be accurate or consistent.
• Many Underdosed Ingredients: As you’ll read below, many ingredients are dosed below what was used in human clinical trials.

Quick Verdict

Thesis has a range of suitable nootropic blends to cater to many needs.

However, our #1 nootropic of choice is Nooceptin. It’s designed for long-term brain changes, not short-term boosts in mental performance.

What Is Thesis Nootropics?

Thesis Nootropics is a company specializing in customized cognitive performance products. It was founded by Dan Freed in 2017.

Freed’s personal challenges with focusing, which he faced from a young age, led him to discover nootropics.

This personal journey of transformation through nootropics inspired him to create Thesis, aiming to help others find the right combination of nootropic ingredients that work for them.

The company’s unique approach involves allowing customers to experiment with high-quality nootropic ingredients to maximize results systematically.

Thesis has gained popularity primarily through word-of-mouth and a strong focus on personalization.

The company has raised over $13.5 million in funding and is reportedly profitable with a robust growth trajectory.

Thesis has garnered support from health and wellness advocates like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.

Thesis Nootropics

Customized Blends For Cognitive Enhancement

Take the quiz and see which blends are right for you.

Thesis Nootropic Ingredients

Thesis have six unique blends designed to target various aspects of cognitive function. What’s similar between them is the option to include or exclude caffeine and L-theanine. The caffeine and l-theanine combination is the most potent instant nootropic, making each blend effective.

The caffeine L-theanine stack benefits physical and cognitive function. Some advantages include faster reaction time, faster visual processing speed, better working memory, increased awareness, and less tiredness and mental fatigue [1] [2] .

The research employs a 2:1 L-theanine to caffeine ratio, which Thesis has followed. Since this stack is available in every blend, I won’t include it in the ingredients breakdown below.

Thesis Clarity Blend

Alpha gpc (speculative).

Alpha GPC, a choline-containing phospholipid, improves cognitive function in neurological conditions like dementia [3] .

Research indicates it enhances memory and attention and may support brain health. Clinical trials show it can improve cognitive performance, especially when combined with other treatments like donepezil [4] .

It’s generally well-tolerated and safe. Alpha GPC increases acetylcholine levels in the brain, which is essential for memory and learning [5] .

It’s used both as a medicine and a nutritional supplement. Studies suggest Alpha GPC effectively boosts cognitive functions, particularly in adult-onset dementia disorders [6] .

Thesis Clarity Blend contains 500 mg, which is more than any other nootropic available.

Lions Mane Mushroom (Speculative)

The Lion’s Mane mushroom (Hericium erinaceus) includes chemicals that stimulate nerve growth factor (NGF) synthesis, which is necessary for nerve cell proliferation and differentiation [7] .

According to research, Lion’s Mane improves cognitive abilities, particularly memory and brain cell regeneration [8] .

It is renowned for its neuroprotective qualities, which may be effective in treating illnesses such as Alzheimer’s disease and cognitive impairment [9] .

Brain functioning, memory, and mood improvements have been linked to regular ingestion [10] .

While the mushroom does not directly improve cognitive skills, it does increase NGF, which improves brain health [11] . The dosage varies but is generally well-tolerated and has few negative effects.

Thesis Clarity contains 500 mg of Lions Mane, which may give a long-term nootropic effect.

Mycelium is typically avoided since the active chemicals are found in the primary mushroom. Jeff Chilton, a long-time mushroom researcher, discusses this in the podcast below:

Camellia Sinensis Tea Leaf (Speculative)

Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used.

Seed extracts tend to be more stimulating, enhancing motor functions and showing potential as an antidepressant without causing drowsiness.

Leaf extracts, on the other hand, tend to produce a calming effect on the mind and mood. Both seeds and leaves have shown positive results in various tests assessing motor function and behavior in animal models [12] .

The study suggests these parts of the Camellia Sinensis plant have potential as cognitive enhancers, warranting further research, especially on seed extracts for their mode of action and possible new beneficial compounds.

I couldn’t find any human studies for this ingredient, so I can’t give you an efficacious dose range. But Thesis Clarity contains 278 mg of Camellia Sinensis Tea Leaf.

Dihydroxyflavone

Dihydroxyflavone research is all performed in rodents, so extrapolating to humans is rather challenging. 7,8-Dihydroxyflavone (7,8-DHF) is a compound that acts as an agonist for the TrkB receptor, which is associated with brain-derived neurotrophic factor (BDNF).

BDNF is crucial for neuronal survival and brain plasticity. Studies have shown that 7,8-DHF can improve memory and cognitive functions [13] .

It enhanced memory formation in healthy rats, and in Alzheimer’s disease mouse models, it improved spatial memory [14] .

Further, 7,8-DHF has been shown to counteract aging-related cognitive impairments in rats, improving spatial memory and synaptic plasticity in the hippocampus [15] .

This suggests that 7,8-DHF is a potential therapeutic agent for memory impairment and dementia, at least in rodents.

Thesis Energy Blend Ingredients

Citicoline is commonly mentioned in relation to memory enhancement. According to studies, 500 mg daily may improve episodic memory or the ability to recall personal experiences and specific events [16] .

According to other research, taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy persons [17] .

The formulation of Thesis Energy Blend contains 300 mg of Citicoline. This dose may not achieve the full potential seen in studies proposing a higher dose.

Mango leaf extract, rich in the polyphenolic compound mangiferin, shows promise in neuropharmacology due to its anti-inflammatory, antioxidant, and antidiabetic properties.

Studies indicate its potential in treating central complications associated with metabolic disorders like type 2 diabetes, which are risk factors for Alzheimer’s disease and vascular dementia [18] .

In animal models, mango leaf extract has demonstrated effects on reducing brain inflammation and spontaneous bleeding and improving cognitive functions [19] .

These findings suggest its utility in addressing symptoms of neurodegenerative diseases and cognitive impairments [20] .

Thesis Energy contains 300 mg of mango leaf.

Theacrine is a purine alkaloid similar to caffeine, found in the Camellia Kucha plant, and often included in dietary supplements.

Studies show that it can increase energy, focus, and cognitive performance, similar to caffeine, but without habituation [21] .

Theacrine’s impact on cognitive performance and physical endurance has been researched in athletes, indicating possible benefits in reaction time and endurance [22] .

It may work well alone or in combination with caffeine to enhance cognitive function and physical performance [23] .

Theacrine appears to be a promising supplement for improving mental alertness and physical capacity. Bear in mind the manufacturers of Theacrine fund some of these studies.

Thesis Energy contains 100 mg of Theacrine, which tends to be less than the dose used in these studies, suggesting it may have a weaker effect.

N-Acetyl Cysteine

N-acetyl cysteine (NAC) is explored for its potential to improve cognitive functions in psychosis and bipolar disorder due to its antioxidant, neurogenesis, and anti-inflammatory properties.

Studies show N-acetyl cysteine can improve working memory in psychosis [24] . However, results in bipolar disorder didn’t show significant cognitive improvements [25] .

Research indicates potential benefits for Alzheimer’s disease by promoting cognitive health and countering oxidative stress [26] .

The effectiveness of N-acetyl cysteine in various cognitive disorders still requires more targeted, larger studies to confirm its benefits [27] .

N-acetyl cysteine’s role is promising but not yet firmly established in cognitive enhancement.

In human trials, it seems a 600 – 2000 mg dose is needed for cognitive benefits. Thesis Energy contains 500 mg, being potentially underdosed.

Indian Trumpet Tree

Indian Trumpet Tree is known as Oroxylum indicum. In a 12-week study, older adults with memory complaints took 500 mg of Oroxylum indicum extract twice daily [28] .

Compared to a placebo, this supplementation led to improvements in episodic memory and numeric working memory. It also accelerated learning in location tasks.

However, there were no significant changes in other cognitive tests or overall cognitive and memory skills.

The study suggests that Oroxylum indicum, while well-tolerated, may primarily enhance specific memory functions.

Its potential effects could be linked to its antioxidant and anti-inflammatory properties and interactions with neurotransmitters like dopamine and GABA.

This is the only human study on the Indian Trumpet Tree, so more research is needed to fully understand its impact on cognitive health. Thesis Energy only contains 100 mg of this, making it potentially underdosed.

L-tyrosine, an amino acid, has been shown to increase dopamine levels in the brain. L-tyrosine supplementation has improved cognitive regulation, particularly in mentally demanding settings [29] .

It is especially helpful in improving cognitive flexibility, which is impacted by dopamine.

While L-Tyrosine’s promise for treating clinical problems and improving physical activity is limited, it is useful in stressful or cognitively taxing situations.

It has the greatest cognitive benefits when neurotransmitter activity is intact, but dopamine and norepinephrine levels are momentarily decreased [30] .

According to research, optimal doses for cognitive improvement begin at a minimum of 2 grams. That is more than six times the dose in Thesis Energy.

Thesis Creativity Blend Ingredients

Thesis Creativity contains 150 mg of Alpha GPC, yet their Clarity Blend contains 500 mg. I’m not sure why there is a large discrepancy, especially when 500 mg is likely a more efficacious dose.

Agmatine Sulfate

Currently, agmatine sulfate has only been tested in rodents. It is a central nervous system (CNS) neurotransmitter/neuromodulator that has been studied for its potential effects on stress-related conditions like depression, anxiety, and cognitive performance.

Research suggests that agmatine can have antidepressant and anxiolytic (anxiety-reducing) effects, possibly related to its influence on the nitric oxide pathway [31] .

It may reduce oxidative stress and corticosterone levels while increasing brain-derived neurotrophic factor (BDNF), which is beneficial for brain health.

Agmatine sulfate has been shown to be safe and well-tolerated in animal studies, with oral administration effectively increasing its levels in the brain [32] .

This indicates potential for therapeutic use in neurological disorders, though more research is needed to fully understand its effects and mechanisms.

Thesis Creativity contains 250 mg. In these studies, patients were administered 15-600 mg per kg, which is a much higher dose.

Panax Ginseng

Panax ginseng is available in two varieties: white ginseng and red ginseng. It has vasorelaxant and moderately hypotensive effects on nitric oxide generation in the body [33] .

It increases antioxidant enzyme activity and may prevent oxidative damage associated with aging in rats [34] .

Ginseng has shown promise in boosting memory, particularly in age-related cognitive decline, as well as in improving mental and physical resilience, reducing fatigue, and assisting the body in adapting to stress [35] .

Daily doses of 200 mg extract or 0.5 to 2 g dry root are recommended. It is not suggested for persons with acute asthma or hypertension because it may cause overstimulation and elevate blood pressure in excessive dosages.

Thesis Creativity has an effective dose of 200 mg, which may provide you with these mental performance benefits.

Ashwagandha Root

Ashwagandha is a traditional herbal remedy used to improve various health conditions. Animal studies have shown that it can increase blood cell counts, which might enhance aerobic capacity [36] .

It also demonstrates the potential to reduce oxidative stress and lipid peroxidation, which could be beneficial in treating disorders like tardive dyskinesia [37] .

Additionally, Ashwagandha has shown nootropic effects and might be useful in treating Alzheimer’s disease [38] . Recommended dosages range from 6 to 10 grams of ground roots or 100 to 1250 mg of extract daily [39] [40] .

It’s generally safe but should be used cautiously, especially in cases of hyperthyroidism or pregnancy. High doses can have sedative effects and may cause gastrointestinal issues.

Thesis Creativity contains 300 mg of Ashwagandha, which is within the recommended range for cognitive benefits.

Sceletium Tortuosum

Sceletium tortuosum, also known as Kanna, is traditionally used for its mood-enhancing properties. It’s been studied for its potential in treating cognitive and neurodegenerative disorders like Alzheimer’s and Parkinson’s [41] .

Research suggests its constituents could target enzymes and receptors relevant to these diseases, offering neuroprotective benefits like antioxidant activity [42] .

Additionally, Sceletium Tortuosum is known for its antidepressant and anxiolytic effects, promoting relaxation and well-being, which could be beneficial in managing stress, anxiety, and depression [43] .

The plant’s bioactive alkaloids are also being explored for commercial medicinal use.

The 25 mg dose in Thesis Creativity is the same as used within the human trials.

Thesis Motivation Blend Ingredients

L-phenylalanine.

L-phenylalanine is a vital amino acid and has been explored for its potential benefits in managing conditions like attention deficit disorder and depression.

In studies, doses of up to 1200 mg showed initial improvements in mood and attention in individuals with attention deficit disorder, but tolerance developed over 2-4 months [44] .

In another study involving depressed patients, a dosage range of 75–200 mg/day for 20 days led to significant improvements in 12 out of 20 patients [45] .

However, the effectiveness and safety of L-phenylalanine can vary, and it is used in the treatment of various conditions, including depression and arthritis, and even as part of addiction recovery [46] .

Thesis Motivation has a 500 mg dose, which may provide some of these benefits. Will it improve motivation? I’m not sure.

Methylliberine

Methylliberine is a purine alkaloid explored for its cognitive and mood-enhancing effects. Studies have shown it can improve concentration, motivation, and mood, especially when combined with caffeine.

Methylliberine also appears to positively affect energy levels and well-being without significantly impacting vital signs like heart rate and blood pressure [47] .

These findings suggest its potential as a nootropic supplement, particularly for enhancing cognitive function and mood in various contexts, such as gaming or in tactical scenarios [48] [49] .

However, it’s essential to consider the dosage and combination with other compounds like caffeine for optimal effects.

The 100 mg dose in Thesis Motivation aligns with the current research.

Vitamin B12 (Speculative)

Vitamin B12 is essential for cognitive health and may be linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Low levels of B12 are associated with cognitive impairment, but supplementation is only shown to be effective in improving cognition in cases of existing B12 deficiency [50] .

There is limited evidence that increasing B12 levels benefits people without B12 deficiency [51] .

B12’s impact on cognitive health may involve multiple mechanisms, including brain volume and function [52] . However, more extensive research is needed to fully understand its effects and potential as a cognitive enhancer.

Thesis Motivation contains 1000mcg. The research states that it may have no effect if you’re not Vitamin B12 deficient.

Forskolin (Speculative)

Forskolin has only been studied in rodents regarding cognitive function. Forskolin is an herbal extract that shows the potential to improve memory and reduce Alzheimer’s disease symptoms.

In studies, it restored nest-building and social behaviors in mice with Alzheimer-like symptoms, reduced amyloid plaque deposition, and regulated brain inflammation [53] .

Forskolin also influences memory and tau protein phosphorylation in the brain, which is relevant in Alzheimer’s [54] .

Additionally, forskolin has shown protective effects against Huntington’s disease-like neurodegeneration in rats by improving learning and memory and reducing oxidative stress [55] .

These findings indicate forskolin’s potential as a neuroprotective agent for certain neurological conditions, at least in rodents.

I’m skeptical whether 250 mg of Forskolin in Thesis Motivation will help you “feel” more motivated.

Artichoke (Speculative)

Artichoke extract is known for its prebiotic properties and promotes probiotic bacteria growth in the gut, potentially benefiting cognitive functions in mice [56] .

In elderly individuals with mild cognitive impairment, combining artichoke extract and aerobic training improved cognitive status and reduced blood glucose and insulin resistance [57] .

Artichoke varieties Spinoso Sardo and Romanesco Siciliano demonstrated antioxidant properties and potential protective effects against cardiovascular and neurodegenerative disorders, with Romanesco Siciliano showing higher antioxidant power [58] .

The 450 mg dose is well under the dose used in these studies.

Thesis Confidence Blend Ingredients

Saffron (speculative).

Saffron is traditionally used in herbal medicine and shows promise in improving cognitive function in individuals with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) [59] .

Research indicates that saffron’s effectiveness is comparable to common drugs used for these conditions without increasing side effects. It’s also well-tolerated in cognitively normal individuals [60] .

However, most current studies have a high risk of bias. More comprehensive, low-bias clinical trials are needed to confirm saffron’s potential as a treatment for cognitive impairments like AD and MCI.

All of the research used 30 mg of saffron daily. Thesis Confidence has 28 mg, and I’m unsure why they formulated it without the extra 2 mg.

Magnesium Bisglycinate

Magnesium is essential for brain functions and has been researched for its potential cognitive benefits. Magnesium is particularly effective in increasing brain magnesium levels and has shown promise in improving memory and cognition in healthy adults [61] .

However, its role in anxiety and mood disorders is less clear [62] .

Studies indicate magnesium may help reduce symptoms of depression, but results are not consistent across all mental health conditions [63] .

Further research is needed to conclusively establish magnesium’s effectiveness and appropriate use as a therapeutic supplement in various psychiatric and cognitive disorders [64] .

500 mg of magnesium may help if you’re deficient, but there’s no clear benefit to making you more confident.

Sage (Speculative)

Sage is known as Salvia and has been traditionally known to enhance memory. A recent study supports this, showing that acute ingestion of sage oil can significantly improve immediate word recall in healthy young adults [65] .

This suggests that sage may positively influence cognitive functions like memory, potentially due to its acetylcholinesterase inhibition activity in the brain.

However, this has not been replicated.

While historically used for various mental disorders, such as depression and age-related memory loss, contemporary research is needed to fully understand its benefits and potential as a cognitive enhancer.

Regardless of the 333 mg dose, this is one of the more speculative ingredients in all Thesis blends.

Sceletium Tortuosum (Speculative)

As mentioned in the Creativity Blend, Sceletium Tortuosum is known for its mood-enhancing properties. It is the same dose of 25 mg, which is used in human trials.

Magnolia Bark (Speculative)

Magnolia officinalis is commonly used in traditional medicine for mental disorders like anxiety and depression and shows potential as a nootropic supplement.

Studies have demonstrated that its ethanol extract can improve cognitive function and memory in stress-induced situations. It also exhibits anxiolytic properties, reducing anxiety-related behaviors in rats [66] .

The extract’s effectiveness is also evident in lowering stress-induced increases in corticosterone and tyrosine hydroxylase levels.

Moreover, Magnolia officinalis, especially its component honokiol, has neuroprotective effects and can regulate mood disorders by modulating GABA and CB1 receptors in rats [67] .

These are rodent studies, so it’s impossible to extrapolate to humans. Regardless, it’s included based on the mechanistic data with the theory of doing the same thing in humans with the 10 mg dose.

Ashwagandha Leaf & Root

The 120 mg of root and leaf ashwagandha may be enough to have a nootropic effect as the extract dose is between 100-1200 mg, as stated in the Creativity Blend section. However, this is root and leaf, and the main benefits are derived from the root.

Thesis Logic Blend Ingredients

Ginko biloba.

Ginkgo biloba is extracted from the leaves and fruit to improve cognitive function. Its compounds include antioxidants, enhance blood flow, and have anti-inflammatory properties.

Ginkgo biloba extract has been shown in animal studies to help with chronic brain difficulties by modifying inflammatory mediators and the cholinergic system [68] .

It has been shown in clinical trials to improve working memory and processing speed [69] . However, its usefulness in healthy people under the age of 60 is debatable [70] .

Typical daily doses vary from 120 to 300 mg. Although side effects are uncommon, they can include stomach irritation and headaches, which may cause blood to thin, affecting people on certain drugs.

Thesis Logic contains 160 mg of Ginkgo Biloba, which is within the recommended dosage range.

Theobromine

Theobromine is a compound found in chocolate and has been studied for its potential cognitive effects.

Research indicates that theobromine might have a lesser immediate nootropic effect compared to caffeine but could have neuroprotective benefits with long-term consumption, possibly reducing Alzheimer’s disease-related pathology [71] .

Further studies are needed to fully understand its impact on cognition.

Additionally, theobromine’s effects on mood and vigilance appear to be different from caffeine, with some studies suggesting it might not significantly influence these aspects in nutritionally relevant doses [72] .

However, combining theobromine with caffeine could modify its effects, potentially offering cognitive and mood benefits without significant blood pressure increases [73] .

More research is required to confirm theobromine’s cognitive and mood-related effects.

Thesis Logic contains 100 mg of theobromine, but it seems doses greater than 400 mg are needed to enhance cognition.

Phosphatidylserine

Phosphatidylserine is essential for proper brain function. Phosphatidylserine has been proven to be critical for maintaining nerve cell membranes and myelin, which is required for successful neurotransmission [74] .

Phosphatidylserine can help reverse cognitive loss as the brain ages by boosting cognitive activities such as memory formation, learning, concentration, and problem-solving [75] .

It is well absorbed in humans and crosses the blood-brain barrier.

Supplements containing phosphatidylserine have been shown to increase cognitive functions and are generally well-tolerated, with dosages ranging from 100 to 800 mg per day advised for cognitive support [76] [77] .

Thesis Logic contains 400 mg of phosphatidylserine, which may provide you with these cognitive-enhancing effects.

High DHA Algae

DHA is a vital component of neuronal membranes and plays an important role in brain health and cognitive function.

Adult cognitive abilities are improved by DHA consumption, especially when paired with eicosapentaenoic acid (EPA) [78] .

This impact is most noticeable in older people who have mild memory problems. Higher DHA and EPA doses (above 1 g per day) have been associated with better episodic memory.

Observational studies also show a link between DHA/EPA intake and memory performance in the elderly. DHA, both alone and in combination with EPA, improves memory in the elderly.

Thesis Logic contains 200 mg of DHA, suggesting insufficient DHA to provide a benefit.

Triacetyluridine (Speculative)

Triacetyluridine is being explored as a potential treatment for bipolar depression. In a study involving eleven patients with bipolar depression, high doses of triacetyluridine (up to 18 g per day) were administered over 6 weeks [79] .

The study measured the effects on depression symptoms using the Montgomery-Asberg Depression Rating Scale (MADRS) and evaluated cellular bioenergetics using phosphorus magnetic resonance spectroscopic imaging (P-MRSI).

Results indicated significant early improvement in depression symptoms.

Additionally, triacetyluridine responders showed notable differences in pH changes from baseline, suggesting triacetyluridine may improve mitochondrial function and reduce symptoms of depression.

Thesis Logic has 30 mg of triacetyluridine, which is well below the dose used in this study.

Bacopa Monnieri

Bacopa monnieri is a traditional plant that has been shown to improve cognitive performance, particularly memory.

Bacopa extract, namely bacosides A and B, has been demonstrated in studies to increase memory formation, recall, and cognitive function [80] .

It has neuroprotective properties and is used to treat cognitive dysfunctions such as Alzheimer’s disease.

Adults should take between 200 and 400 mg each day. Bacopa is generally well accepted, with only rare reports of mild drowsiness or stomach difficulties.

Clinical trials show that older people have better memory, attention, mood, and overall cognitive ability [81] [82] [83] . More research is needed, however, to thoroughly grasp its usefulness across many cognitive domains.

Thesis Logic contains 320 mg of Bacopa, giving you the efficacious dose to feel these benefits.

Thesis Nootropics Price

Thesis has two options: one time purchase or a subscription. Here’s how the prices break down:

• Subscription = $79
• One Time Purchase = $119

This is regardless of whether you purchase a personalized starter kit or build your own box.

You can’t buy them individually either. You must purchase 4 boxes. When building your own, you can choose if you want 4 of the same blend or mix and match.

They want you to try each blend for a week as part of the starter kit (there’s only a week’s worth of each blend in each container) to see which you like best.

Thesis has positioned itself as the most expensive nootropic available by adding the personalized element.

Is Thesis Nootropics Really Personalized?

I went through the initial quiz to see how they “personalize” their nootropic stack.

Here is what they recommended me:

Look, I get the marketing angle. In no way is this a truly personalized nootropic product. It’d be nearly impossible to create custom formulations for every unique individual.

However, the fact they have multiple blends means people can experiment to find which works best for them.

I will say, though, if you choose the caffeine options, every blend will work. Many of the ingredients used in these blends are speculative and only based on animal research, with many being underdosed.

Benefits Of Thesis Nootropics

Multiple blends for different purposes.

To be honest, this benefit is more of a marketing tactic. However, some people may find certain blends jive well with them over others, giving you options within the same brand.

Further, Thesis claims the ingredients in each formulation work synergistically. There’s no research to back that claim, but at least know there are no negative side effects from their interaction.

Options For Stimulants Or Not

You can choose whether or not you want stimulants within your Thesis Blends. Every blend will provide similar benefits if you add the caffeine and L-theanine nootropic stack, which is the most potent synergistic brain booster.

However, if you’re already a coffee addict or plan to take Thesis in the evening, having no stimulants is the better option.

My Experience With Thesis

Based on my quiz, I was recommended Thesis Clarity, Logic, Motivation, and Confidence Blends. I tried each for a week to see if one stood out. I took them without caffeine as they all work if you have the caffeine L-theanine stack.

I have to say the Confidence and Motivation Blends did absolutely nothing for me. I didn’t “feel” any brain-boosting effects or feel more confident or motivated.

I felt the Logic and Clarity Blends had small positive effects when concentrating on mentally demanding tasks like writing, coaching, or podcasting.

If I were to continue taking Thesis, I’d opt for either of these two blends.

Who Is Thesis For?

Busy working professionals.

Thesis Nootropics are ideal for busy professionals facing demanding schedules and high-stress environments. These blends can help enhance focus, improve decision-making, and increase productivity.

They are designed to support sustained mental energy throughout the day, enabling professionals to manage their workload more effectively without the usual mental fatigue.

Creative Artists

For creative artists, Thesis offers blends that stimulate creativity and enhance divergent thinking. These nootropics can aid in breaking through creative blocks, fostering innovative thinking, and maintaining a heightened state of inspiration.

They are particularly beneficial for artists seeking longer periods of creative flow and those seeking fresh perspectives.

Students can significantly benefit from Thesis Nootropics, especially during intense studying or when facing challenging academic projects.

The blends are formulated to enhance memory retention, improve concentration, and boost learning capabilities. This makes them a valuable tool for students who need to absorb and retain large amounts of information and perform well in academic assessments.

Gamers find Thesis Nootropics beneficial for improving their gaming performance. The blends can enhance reaction times, increase focus, and improve strategic thinking skills.

They are particularly useful during long gaming sessions, helping gamers stay alert and responsive, which is crucial in competitive gaming scenarios.

Coffee Haters

Thesis Nootropics provides an excellent alternative for those who dislike coffee or want to avoid caffeine jitters.

These blends offer a way to boost mental energy and alertness without relying on caffeine. This makes them ideal for individuals sensitive to caffeine or those seeking to reduce caffeine intake while maintaining high cognitive function.

User Testimonials And Reviews

You can’t access the review database on the Thesis website, so I did some digging to find user reviews. Here’s a couple of positive reviews:

“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.” – ParsnipExtreme2502 (Reddit)

“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.” – leftylucy88 (Reddit)

I can’t find many negative reviews other than potential side effects like migraines, which can be caused by many different factors.

Thesis Side Effects

Side effects are rare from the ingredients in these blends. I personally didn’t have any adverse reactions to the four blends I tried. However, like any supplement, they may have potential side effects.

Consult with a healthcare provider before starting any nootropic regimen, especially if they have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.

Thesis Alternatives

If Thesis Nootropics isn’t quite the right match for you or you’re just curious about other products, here are some alternatives I’ve tried and can provide an insider’s look into.

SAP Nutra nootropic Nooceptin improves memory, concentration, and cognitive performance without stimulants. It offers gradual brain health gains.

It improves memory and focus and provides a prolonged boost without a caffeine crash. Students, gamers, professionals, and seniors should use Nooceptin to boost cognition.

This brain supplement contains Lion’s Mane Extract, Citicoline, Rhodiola Rosea Extract, L-Theanine, Bacopa Monnieri, Ginkgo Biloba, and Panax Ginseng.

Some of these compounds have been shown to be useful, but others are experimental. Nooceptin, a non-stimulant method for long-term cognitive enhancement, usually works after 7-14 days.

Despite the risk of underdosed components and increased cost, Nooceptin may provide a stimulant-free cognitive boost.

Read more in our Nooceptin review .

Mind Lab Pro

Mind Lab Pro is a popular nootropic that has gained appeal as a result of its alleged cognitive benefits.

Pure substances are used in its formulation, which is intended to improve mental clarity and attention. It is stimulant-free, making it an excellent choice for anyone seeking a well-rounded routine.

Its unique combination of 11 research-backed components distinguishes it from competitors in the brain health supplement sector.

These compounds were carefully chosen to help cognitive processes like memory, focus, mental clarity, mood, and cognitive processing speed.

Despite some criticism about the quantity of specific substances and the need for more scientific data, Mind Lab Pro has earned worldwide recognition for its ability to improve cognitive performance in professionals, students, the elderly, and athletes.

Our Mind Lab Pro review goes into great detail.

Braini distinguishes itself by being stimulant-free, providing long-term results, and having a short ingredient list focusing on long-term cognitive gains. It does not, however, deliver the immediate euphoric boost that some users may expect from a brain supplement.

Peptylin, a silk protein peptide with neuroprotective effects and potential benefits for executive function; NeurXcel, which is rich in omega fatty acids; and Wild Canadian Blueberry extract, which is known for its antioxidant characteristics and cognitive support, are all key ingredients in Braini.

Braini is backed by clinical trials, a 60-day money-back guarantee, and a 30-day challenge to scientifically quantify changes in brain function.

Our Braini review contains an in-depth breakdown.

Vyvamind is a nootropic supplement containing caffeine and L-theanine to help focus and improve cognitive performance. Users claim increased focus, vitality, and cognitive abilities without big crashes.

Vyvamind’s formulation, which contains less L-tyrosine and citicoline than some studies suggest, is intended to supplement the major nootropic duo of caffeine and L-theanine.

This combination is well-known for boosting concentration and cognitive function. The supplement is touted as a non-stimulant alternative, appealing to clients seeking a more natural and less intensive approach to cognitive growth.

Vyvamind is suitable for coffee-averse people, busy professionals who require a focus boost, and students during study sessions.

Our Vyvamind review goes into great detail.

Because of its purported fast cognitive effects, NooCube is a popular brain-boosting product. NooCube contains ingredients such as Bacopa Monnieri, L-Tyrosine, and L-Theanine.

These are well-known for their mental health advantages. Several compounds, such as Huperzine-A and Alpha GPC, remain speculative without additional investigation.

NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are clearly labeled.

Because it gives different cognitive benefits without the jittery side effects associated with caffeine, NooCube is especially good for working professionals, students, elders, gamers, and combat athletes.

Our detailed analysis can be found in our NooCube review .

Frequently Asked Questions

What is thesis nootropic and what does it do.

Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Users can expect improvements in focus, reduction in procrastination, stress management, and memory recall, depending on which blend you choose.

Does Thesis Work Like Adderall?

Thesis Nootropics and Adderall are used to enhance cognitive functions, but they are fundamentally different. Adderall is primarily prescribed for treating Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.

Adderall is an amphetamine, classified as a controlled substance due to its strong stimulating effects and potential for abuse and dependency.

Thesis Nootropics are dietary supplements designed to enhance healthy individuals’ cognitive functions, such as memory, focus, and mental clarity. They are not intended to treat medical conditions like ADHD.

How Long Does It Take Thesis Nootropics To Work?

If you have the caffeine version, within 30 minutes. You may feel the non-stimulant blends kicking in just as quickly, but they won’t be as pronounced. Sometimes, they can take multiple weeks to feel them working.

I’ve taken a deep dive into the world of nootropics and shared my firsthand experience with Thesis Nootropic’s various blends. While the personalization is nothing more than a marketing tactic, the different blends are a nice touch for those who want to experiment with different ingredients.

• Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., & Scholey, A. B. (2008). The effects of L-theanine, caffeine and their combination on cognition and mood. Biological psychology, 77(2), 113-122.
• Owen, G. N., Parnell, H., De Bruin, E. A., & Rycroft, J. A. (2008). The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutritional neuroscience, 11(4), 193-198.
• Traini, E., Bramanti, V., & Amenta, F. (2013). Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline-containing phospholipid with a still interesting profile as cognition enhancing agent. Current Alzheimer Research, 10(10), 1070-1079.
• Sagaro, G. G., Traini, E., & Amenta, F. (2023). Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis. Journal of Alzheimer’s Disease, (Preprint), 1-12.
• Kansakar, U., Trimarco, V., Mone, P., Varzideh, F., Lombardi, A., & Santulli, G. (2023). Choline supplements: An update. Frontiers in Endocrinology, 14, 1148166.
• Moreno, M. D. J. M. (2003). Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clinical therapeutics, 25(1), 178-193.
• Lai, P. L., Naidu, M., Sabaratnam, V., Wong, K. H., David, R. P., Kuppusamy, U. R., … & Malek, S. N. A. (2013). Neurotrophic properties of the Lion’s mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International journal of medicinal mushrooms, 15(6).
• La Monica, M. B., Raub, B., Ziegenfuss, E. J., Hartshorn, S., Grdic, J., Gustat, A., … & Ziegenfuss, T. N. (2023). Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion’s Mane Extracts on Cognitive Performance. Nutrients, 15(24), 5018.
• Chong, P. S., Fung, M. L., Wong, K. H., & Lim, L. W. (2020). Therapeutic potential of Hericium erinaceus for depressive disorder. International journal of molecular sciences, 21(1), 163.
• Docherty, S., Doughty, F. L., & Smith, E. F. (2023). The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients, 15(22), 4842.
• Phan, C. W., Lee, G. S., Hong, S. L., Wong, Y. T., Brklja?a, R., Urban, S., … & Sabaratnam, V. (2014). Hericium erinaceus (Bull.: Fr) Pers. cultivated under tropical conditions: isolation of hericenones and demonstration of NGF-mediated neurite outgrowth in PC12 cells via MEK/ERK and PI3K-Akt signaling pathways. Food & Function, 5(12), 3160-3169.
• Rubab, S., Rizwani, G. H., Bahadur, S., Shah, M., Alsamadany, H., Alzahrani, Y., … & Zaman, W. (2020). Neuropharmacological potential of various morphological parts of Camellia sinensis L. Saudi Journal of Biological Sciences, 27(1), 567-573.
• Bollen, E., Vanmierlo, T., Akkerman, S., Wouters, C., Steinbusch, H. M. W., & Prickaerts, J. (2013). 7, 8-Dihydroxyflavone improves memory consolidation processes in rats and mice. Behavioural brain research, 257, 8-12.
• Zeng, Y., Lv, F., Li, L., Yu, H., Dong, M., & Fu, Q. (2012). 7, 8?dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats. Journal of neurochemistry, 122(4), 800-811.
• Han, M., Zhang, J. C., Huang, X. F., & Hashimoto, K. (2017). Intake of 7, 8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation. European Archives of Psychiatry and Clinical Neuroscience, 267, 479-483.
• Nakazaki, E., Mah, E., Sanoshy, K., Citrolo, D., & Watanabe, F. (2021). Citicoline and memory function in healthy older adults: a randomized, double-blind, placebo-controlled clinical trial. The Journal of Nutrition, 151(8), 2153-2160.
• Jasielski, P., Pi?del, F., Piwek, M., Rocka, A., Petit, V., & Rejdak, K. (2020). Application of citicoline in neurological disorders: a systematic review. Nutrients, 12(10), 3113.
• Infante?Garcia, C., Jose Ramos?Rodriguez, J., Marin?Zambrana, Y., Teresa Fernandez?Ponce, M., Casas, L., Mantell, C., & Garcia?Alloza, M. (2017). Mango leaf extract improves central pathology and cognitive impairment in a type 2 diabetes mouse model. Brain Pathology, 27(4), 499-507.
• Garcia-Partida, J. A., Torres-Sanchez, S., MacDowell, K., Fernández-Ponce, M. T., Casas, L., Mantell, C., … & Berrocoso, E. (2022). The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia. Frontiers in Pharmacology, 13, 886514.
• Wightman, E. L., Jackson, P. A., Forster, J., Khan, J., Wiebe, J. C., Gericke, N., & Kennedy, D. O. (2020). Acute effects of a polyphenol-rich leaf extract of mangifera indica l.(zynamite) on cognitive function in healthy adults: A double-blind, placebo-controlled crossover study. Nutrients, 12(8), 2194.
• Kuhman, D. J., Joyner, K. J., & Bloomer, R. J. (2015). Cognitive performance and mood following ingestion of a theacrine-containing dietary supplement, caffeine, or placebo by young men and women. Nutrients, 7(11), 9618-9632.
• Dillon, H., & Steven, M. (2021). Theacrine as a Potential Caffeine Alternative for Enhanced Ergogenic and Cognitive Performance in Athletes: A Call to Action and Brief Review. Journal of Exercise and Nutrition, 4(3).
• Bello, M. L., Walker, A. J., McFadden, B. A., Sanders, D. J., & Arent, S. M. (2019). The effects of TeaCrine® and caffeine on endurance and cognitive performance during a simulated match in high-level soccer players. Journal of the International Society of Sports Nutrition, 16(1), 1-10.
• Rapado-Castro, M., Dodd, S., Bush, A. I., Malhi, G. S., Skvarc, D. R., On, Z. X., … & Dean, O. M. (2017). Cognitive effects of adjunctive N-acetyl cysteine in psychosis. Psychological medicine, 47(5), 866-876.
• Dean, O. M., Bush, A. I., Copolov, D. L., Kohlmann, K., Jeavons, S., Schapkaitz, I., … & Berk, M. (2012). Effects of N?acetyl cysteine on cognitive function in bipolar disorder. Psychiatry and clinical neurosciences, 66(6), 514-517.
• Skvarc, D. R., Dean, O. M., Byrne, L. K., Gray, L., Lane, S., Lewis, M., … & Marriott, A. (2017). The effect of N-acetylcysteine (NAC) on human cognition–A systematic review. Neuroscience & Biobehavioral Reviews, 78, 44-56.
• Lopresti, A. L., Smith, S. J., Majeed, M., & Drummond, P. D. (2021). Effects of an Oroxylum indicum Extract (Sabroxy®) on cognitive function in adults with self-reported mild cognitive impairment: a randomized, double-blind, placebo-controlled study. Frontiers in Aging Neuroscience, 13, 728360.
• Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia, 69, 50-55.
• Jongkees, B. J., Hommel, B., Kühn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands—A review. Journal of psychiatric research, 70, 50-57.
• Gawali, N. B., Bulani, V. D., Gursahani, M. S., Deshpande, P. S., Kothavade, P. S., & Juvekar, A. R. (2017). Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway. Brain research, 1663, 66-77.
• Bergin, D. H., Jing, Y., Williams, G., Mockett, B. G., Zhang, H., Abraham, W. C., & Liu, P. (2019). Safety and neurochemical profiles of acute and sub-chronic oral treatment with agmatine sulfate. Scientific reports, 9(1), 12669.
• Yu, J., Eto, M., Akishita, M., Kaneko, A., Ouchi, Y., & Okabe, T. (2007). Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: a possible involvement of androgen receptor. Biochemical and biophysical research communications, 353(3), 764-769.
• Fu, Y., & Ji, L. L. (2003). Chronic ginseng consumption attenuates age-associated oxidative stress in rats. The Journal of nutrition, 133(11), 3603-3609.
• Nocerino, E., Amato, M., & Izzo, A. A. (2000). The aphrodisiac and adaptogenic properties of ginseng. Fitoterapia, 71, S1-S5.
• Ziauddin, M., Phansalkar, N., Patki, P., Diwanay, S., & Patwardhan, B. (1996). Studies on the immunomodulatory effects of Ashwagandha. Journal of ethnopharmacology, 50(2), 69-76.
• Naidu, P. S., Singh, A., & Kulkarni, S. K. (2006). Effect of Withania somnifera root extract on reserpine?induced orofacial dyskinesia and cognitive dysfunction. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(2), 140-146.
• Bhattacharya, S. K., Kumar, A., & Ghosal, S. (1995). Effects of glycowithanolides from Withania somnifera on an animal model of Alzheimer’s disease and perturbed central cholinergic markers of cognition in rats. Phytotherapy research, 9(2), 110-113.
• Raut, A. A., Rege, N. N., Tadvi, F. M., Solanki, P. V., Kene, K. R., Shirolkar, S. G., … & Vaidya, A. B. (2012). Exploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteers. Journal of Ayurveda and integrative medicine, 3(3), 111.
• Bonilla, D. A., Moreno, Y., Gho, C., Petro, J. L., Odriozola-Martínez, A., & Kreider, R. B. (2021). Effects of Ashwagandha (Withania somnifera) on physical performance: Systematic review and bayesian meta-analysis. Journal of functional morphology and kinesiology, 6(1), 20.
• Chiu, S., Gericke, N., Farina-Woodbury, M., Badmaev, V., Raheb, H., Terpstra, K., … & Goble, L. (2014). Proof-of-concept randomized controlled study of cognition effects of the proprietary extract Sceletium tortuosum (Zembrin) targeting phosphodiesterase-4 in cognitively healthy subjects: implications for Alzheimer’s dementia. Evidence-based complementary and alternative medicine, 2014.
• Luo, Y., Shan, L., Xu, L., Patnala, S., Kanfer, I., Li, J., … & Jun, X. (2022). A network pharmacology-based approach to explore the therapeutic potential of Sceletium tortuosum in the treatment of neurodegenerative disorders. Plos one, 17(8), e0273583.
• Manganyi, M. C., Bezuidenhout, C. C., Regnier, T., & Ateba, C. N. (2021). A chewable cure “kanna”: biological and pharmaceutical properties of Sceletium tortuosum. Molecules, 26(9), 2557.
• Wood, D. R., Reimherr, F. W., & Wender, P. H. (1985). Treatment of attention deficit disorder with DL-phenylalanine. Psychiatry Research, 16(1), 21-26.
• Beckmann, H., Strauss, M. A., & Ludolph, E. (1977). Dl-phenylalanine in depressed patients: an open study. Journal of Neural Transmission, 41(2-3), 123-134.
• Akram, M., Daniyal, M., Ali, A., Zainab, R., Shah, S. M. A., Munir, N., & Tahir, I. M. (2020). Role of phenylalanine and its metabolites in health and neurological disorders. In Synucleins-Biochemistry and Role in Diseases. IntechOpen.
• La Monica, M. B., Raub, B., Malone, K., Hartshorn, S., Grdic, J., Gustat, A., & Sandrock, J. (2023). Methylliberine Ingestion Improves Various Indices of Affect but Not Cognitive Function in Healthy Men and Women. Nutrients, 15(21), 4509.
• La Monica, M. B., Listman, J. B., Donovan, I., Johnson, T. E., Heeger, D. J., & Mackey, W. E. (2021). Effects of TeaCrine®(theacrine), Dynamine™(methylliberine), and caffeine on gamer psychomotor performance in a first-person shooter video game scenario. BioRxiv, 2021-04.
• Cintineo, H. P., Bello, M. L., Chandler, A. J., Cardaci, T. D., McFadden, B. A., & Arent, S. M. (2022). Effects of caffeine, methylliberine, and theacrine on vigilance, marksmanship, and hemodynamic responses in tactical personnel: a double-blind, randomized, placebo-controlled trial. Journal of the International Society of Sports Nutrition, 19(1), 543-564.
• Moore, E., Mander, A., Ames, D., Carne, R., Sanders, K., & Watters, D. (2012). Cognitive impairment and vitamin B12: a review. International psychogeriatrics, 24(4), 541-556.
• Malouf, R., Areosa Sastre, A., & Cochrane Dementia and Cognitive Improvement Group. (1996). Vitamin B12 for cognition. Cochrane Database of Systematic Reviews, 2010(1).
• Tangney, C. C., Aggarwal, N. T., Li, H., Wilson, R. S., Decarli, C., Evans, D. A., & Morris, M. C. (2011). Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination. Neurology, 77(13), 1276-1282.
• Owona, B. A., Zug, C., Schluesener, H. J., & Zhang, Z. Y. (2016). Protective effects of forskolin on behavioral deficits and neuropathological changes in a mouse model of cerebral amyloidosis. J Neuropathol Exp Neurol, 75(7), 618-627.
• Tian, Q., Zhang, J. X., Zhang, Y., Wu, F., Tang, Q., Wang, C., … & Wang, J. Z. (2009). Biphasic effects of forskolin on tau phosphorylation and spatial memory in rats. Journal of Alzheimer’s Disease, 17(3), 631-642.
• Mehan, S., Parveen, S., & Kalra, S. (2017). Adenyl cyclase activator forskolin protects against Huntington’s disease-like neurodegenerative disorders. Neural regeneration research, 12(2), 290.
• Szewczyk, A., Andres-Mach, M., Zagaja, M., Kaczmarczyk-Ziemba, A., Maj, M., & Szala-Rycaj, J. (2023). The Effect of a Diet Enriched with Jerusalem artichoke, Inulin, and Fluoxetine on Cognitive Functions, Neurogenesis, and the Composition of the Intestinal Microbiota in Mice. Current Issues in Molecular Biology, 45(3), 2561-2579.
• Ghahramani, M., Zare, Y., & Kohanpour, M. A. (2021). The Effect of Consuming Artichoke Extract with Aerobic Training on Blood Glucose and Insulin Resistance and Its Relationship with the Cognitive Status in Elderly with Mild Cognitive Impairment. Journal of Sport Biosciences, 13(4), 439-450.
• Iglesias-Carres, L., Bruno, A., D’Antuono, I., Linsalata, V., Cardinali, A., & Neilson, A. P. (2023). In vitro evidences of the globe artichoke antioxidant, cardioprotective and neuroprotective effects. Journal of Functional Foods, 107, 105674.
• Avgerinos, K. I., Vrysis, C., Chaitidis, N., Kolotsiou, K., Myserlis, P. G., & Kapogiannis, D. (2020). Effects of saffron (Crocus sativus L.) on cognitive function. A systematic review of RCTs. Neurological Sciences, 41, 2747-2754.
• Ayati, Z., Yang, G., Ayati, M. H., Emami, S. A., & Chang, D. (2020). Saffron for mild cognitive impairment and dementia: A systematic review and meta-analysis of randomised clinical trials. BMC Complementary Medicine and Therapies, 20, 1-10.
• Zhang, C., Hu, Q., Li, S., Dai, F., Qian, W., Hewlings, S., … & Wang, Y. (2022). A Magtein®, Magnesium L-Threonate,-Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults. Nutrients, 14(24), 5235.
• Boyle, N. B., Lawton, C., & Dye, L. (2017). The effects of magnesium supplementation on subjective anxiety and stress—a systematic review. Nutrients, 9(5), 429.
• Botturi, A., Ciappolino, V., Delvecchio, G., Boscutti, A., Viscardi, B., & Brambilla, P. (2020). The role and the effect of magnesium in mental disorders: a systematic review. Nutrients, 12(6), 1661.
• Phelan, D., Molero, P., Martinez-Gonzalez, M. A., & Molendijk, M. (2018). Magnesium and mood disorders: systematic review and meta-analysis. BJPsych open, 4(4), 167-179.
• Tildesley, N. T., Kennedy, D. O., Perry, E. K., Ballard, C. G., Savelev, S. A. W. K., Wesnes, K. A., & Scholey, A. B. (2003). Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers. Pharmacology Biochemistry and Behavior, 75(3), 669-674.
• Lee, H. K., & Lee, U. J. (2015). Effects of Ethanol Extract from Magnolia Officinalis on Anxiety and Cognitive Function. The Journal of Internal Korean Medicine, 36(4), 507-517.
• Borgonetti, V., Governa, P., Manetti, F., Miraldi, E., Biagi, M., & Galeotti, N. (2021). A honokiol-enriched Magnolia officinalis Rehder & EH Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor. Journal of Pharmacy and Pharmacology, 73(9), 1161-1168.
• Kim, M. S., Bang, J. H., Lee, J., Han, J. S., Baik, T. G., & Jeon, W. K. (2016). Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system. Phytomedicine, 23(12), 1356-1364.
• Stough, C., Clarke, J., Lloyd, J., & Nathan, P. J. (2001). Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants. International Journal of Neuropsychopharmacology, 4(2), 131-134.
• Canter, P. H., & Ernst, E. (2007). Ginkgo biloba is not a smart drug: an updated systematic review of randomised clinical trials testing the nootropic effects of G. biloba extracts in healthy people. Human Psychopharmacology: Clinical and Experimental, 22(5), 265-278.
• Cova, I., Leta, V., Mariani, C., Pantoni, L., & Pomati, S. (2019). Exploring cocoa properties: is theobromine a cognitive modulator?. Psychopharmacology, 236, 561-572.
• Judelson, D. A., Preston, A. G., Miller, D. L., Muñoz, C. X., Kellogg, M. D., & Lieberman, H. R. (2013). Effects of theobromine and caffeine on mood and vigilance. Journal of clinical psychopharmacology, 33(4), 499-506.
• Mitchell, E. S., Slettenaar, M., Vd Meer, N., Transler, C., Jans, L., Quadt, F., & Berry, M. (2011). Differential contributions of theobromine and caffeine on mood, psychomotor performance and blood pressure. Physiology & behavior, 104(5), 816-822.
• Glade, M. J., & Smith, K. (2015). Phosphatidylserine and the human brain. Nutrition, 31(6), 781-786.
• Cenacchi, T., Bertoldin, T., Farina, C., Fiori, M. G., Crepaldi, G., Azzini, C. F., … & Allegro, L. (1993). Cognitive decline in the elderly: a double-blind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration. Aging Clinical and Experimental Research, 5, 123-133.
• Kang, E. Y., Cui, F., Kim, H. K., Nawaz, H., Kang, S., Kim, H., … & Go, G. W. (2022). Effect of phosphatidylserine on cognitive function in the elderly: A systematic review and meta-analysis. ????????, 54(1), 52-58.
• Ma, X., Li, X., Wang, W., Zhang, M., Yang, B., & Miao, Z. (2022). Phosphatidylserine, inflammation, and central nervous system diseases. Frontiers in Aging Neuroscience, 14, 975176.
• Yurko-Mauro, K., Alexander, D. D., & Van Elswyk, M. E. (2015). Docosahexaenoic acid and adult memory: a systematic review and meta-analysis. PloS one, 10(3), e0120391.
• Jensen, J. E., Daniels, M., Haws, C., Bolo, N. R., Lyoo, I. K., Yoon, S. J., … & Renshaw, P. F. (2008). Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients. Experimental and Clinical Psychopharmacology, 16(3), 199.
• Singh, H. K., & Dhawan, B. N. (1997). NEUROPSYCHOPHARMACOLOGICAL EFFECTS OF THE AYURVEDIC NOOTROPlC BACOPA MONNlERA LINN.(BRAHMI). Indian Journal of Pharmacology, 29(5), 359-365.
• Calabrese, C., Gregory, W. L., Leo, M., Kraemer, D., Bone, K., & Oken, B. (2008). Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. The journal of alternative and complementary medicine, 14(6), 707-713.
• Kongkeaw, C., Dilokthornsakul, P., Thanarangsarit, P., Limpeanchob, N., & Scholfield, C. N. (2014). Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. Journal of ethnopharmacology, 151(1), 528-535.
• Pase, M. P., Kean, J., Sarris, J., Neale, C., Scholey, A. B., & Stough, C. (2012). The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. The Journal of Alternative and Complementary Medicine, 18(7), 647-652.

Affiliate Disclosure:

The links provided may earn us a small commission at no additional cost to you if you choose to purchase the recommended product. This support allows our research and editorial team to continue providing high-quality recommendations. As a participant in the Amazon Services LLC Associates Program, an affiliate advertising initiative, we are able to earn advertising fees through providing links to products on Amazon.com. Please rest assured that we only recommend high-quality products.

No related posts.

Submit Video

Report this.

Error: Contact form not found.

Share this video

• Attention and Focus Energy Memory Mood

Thesis: The Personalized, Just for You Nootropics Experience

Wondering if Thesis is right for you? Let’s take a deep dive into the Thesis process and formulas so you can decide for yourself whether Thesis is the nootropics solution for you.

From the minute you take the short quiz that generates a personalized formula to the moment you receive the starter pack of nootropic goodies, Thesis provides you a custom experience unlike any nootropic or supplement you’ve ever tried before.

What makes Thesis unique is that they do all the legwork for you. With coaching support, they’ll narrow down what will likely work best for you, then you have the opportunity to experiment with over thirty high-quality ingredients in a systematic way that yields real results.

Thesis will help you find a blend that’s tailored to your goals, lifestyle, and genetics — for a custom, made just for you nootropic experience.

How Thesis Works

Whether you’re a seasoned fan of Thesis nootropics or just wondering how Thesis personalized formulas can fire up your brainpower, here are all the details you need.

Take the quick and easy quiz to find the right formula for you. You’ll just have to answer a few simple questions about your lifestyle and goals…and then swoosh the system generates a shiny new set of nootropic recommendations just for you. How is Thesis able to determine exactly what’s likely to help you the most? Well, their formulas are rooted in cutting-edge science and then melded with data collected from over 30K customers.

The result is spot-on, ridiculously accurate recommendations every time.

Thesis will send you a four-week starter pack. This is where the fun begins. You’ll experience the magic of nootropics. Feel the difference as your neurotransmitters begin to fire differently. And get to know how your formula makes you feel.

Step Three:

Now, it’s time to tweak. Maybe once your brain fog clears, you realize you need a little more energy in the mornings. Or you thought your mood was your main concern but turns out you really need a bit of a boost in the focus and memory department, too. The best part? You d

on’t have to figure all of this out on your own. Thesis’ expert coaches will help you figure out how to best maximize your supplements and find your brain bliss.

What To Expect From Thesis

Thesis formulas are designed to help you accomplish your goals. Thesis is crafted from the highest-quality, U.S.-sourced ingredients and their formulas are manufactured in FDA-certified facilities. They’re also third-party verified for purity and quality. In short, you can trust every one of their ingredients to bring you the brain boost you want and the peace of mind you need — you can rest easy knowing Thesis products are safely created and sourced.

Receiving Your First Shipment

If you were to explore this process on your own, it would cost over $800, take six months to complete, and would likely not provide the same results.

When you get your first shipment of Thesis, it’s kind of like the first day of the rest of your life. After you do a happy dance and open your package, you’ll find all of the details and instructions you need to make sure you get the most of your specific formula.

As a general rule, it’s recommended to:

• Take your Thesis early in the day (or about thirty minutes before an important task)
• Take your Thesis on an empty stomach
• Keep a log of your Thesis journey. Taking notes regarding your mood, focus, and energy levels can help you realize how far you’ve come…and figure out what else you need to feel your absolute best
• When in doubt, reach out. You can book a consult with a nootropics expert at any time on the Thesis website, or reach out via email, phone, or text.

How Thesis Makes You Feel

Don’t be surprised if you feel something pretty quickly. Thesis formulas are designed to give you totally crash-free improvements in mood, focus, and energy right off the bat.

You’ll also notice that your results compound over time. You’ll be able to tell after a month or so that your brain is stronger than it was before.

But everyone’s brain is different, and nootropics are not a one-size-fits-all solution.

Which is why Thesis offers you the flexibility to tinker with your formula as much as you need to… to get to the other side of optimization. The other side is a pretty sweet place to be, too. It feels like banishing brain fog, finding your motivation , ditching procrastination, and generally getting unstuck from those pesky neurotransmitter imbalances that are holding you back from living your best life.

Some folks require a bit of an adjustment period, and it takes them a bit longer to feel the effects of their Thesis stack. If that’s you, don’t worry. If you stick with it and commit to finding your perfect blend, you’ll find the benefits you’re after.

Long Term Benefits Of Taking Thesis

One of the things we love about nootropics is that their benefits compound over time. Which means the longer you stick with your Thesis regimen, the better your brain will respond.

What Happens If You Don’t Love Your Nootropic Stack?

You don’t have to commit to a formula or an ingredient that you don’t love. With Thesis, you can adjust your stack infinitely until you find the one that works best for you.

Which Thesis Formula Should I Take?

Which Thesis formula you choose is based entirely on your goals, genetics, and lifestyle.

But if you have an idea of what you’d like to enhance in your brain, here’s an outline of the basic blends and some of the key ingredients they include.

This formula helps get those creative juices flowing. For those times where you feel stuck, frustrated, and unable to move past your blocks.

Our Clarity formula is kind of like a chill pill. It helps you become a calm, focused zen master — no matter how stressful your situation may be.

Motivation you can access at will, plus the self-discipline and focus to make things happen? That’s the kind of procrastination buster Motivation is.

If your energy’s low, it’s hard to accomplish much. Which is where our energy formula comes in. This crash-free formulation is our most stimulating, which means it gives you the get-up and go you need to get stuff done. It also means that you may no longer find the need for coffee in the morning.

Logic is the formula to turn to when you need to tackle a big project. It’s kind of like a real-life thinking cap.

Feel The Thesis Difference For Yourself

Pop on over and take the short quiz . It will only take a few minutes, promise! Within days, you’ll be able to check out your starter pack and be well on your way to optimizing your brainpower.

Click here to take the quiz and get started.

References [ + ]

Fact Checking Process

The Neuropedia team is committed to delivering content that adheres to the highest editorial standards for accuracy, sourcing, and objective analysis. Every news article is thoroughly fact-checked by members of our editorial team. Furthermore, we have a zero-tolerance policy regarding any level of plagiarism or malicious intent from our writers and contributors.

All Neuropedia articles adhere to the following standards:

• We only cite reputable sources when researching our guides and articles. These include peer-reviewed journals, government reports, academic and medical associations, and interviews with credentialed medical experts and practitioners.
• All scientific data and information must be backed up by at least one reputable source. Each guide and article includes a comprehensive bibliography with full citations and links to the original sources.
• When we pull a direct quote or a relevant statistic from a study or scientific source, we clearly cite the source we are drawing upon. If the source has not already been linked, we will provide one.
• Similarly, we aim to include all relevant information about our topics.
• Some guides and articles feature links to other relevant Neuropedia pages. These internal links are intended to improve ease of navigation across the site, and are never used as original sources for scientific data or information. Please speak with your doctor if you have medical concerns.
• We strive to have a board of medical experts look over our articles to prevent misinformation and medical myths from spreading. Should our experts encounter erroneous information, we will eliminate it from the final copy.
• If there’s a potential conflict of interest that brings a study or source’s conclusion into doubt, we will hasten to mention it for clarity and completion’s sake. We also understand that medical understanding and scifientic can change over time, so we will include competing theories and conclusions where appropriate.

Thesis Nootropic Review - Do Personalized Nootropics Work? I Found Out.

O dds are if you hadn’t heard about nootropics before the early 2010s, you’ve heard about them now. Nootropics burst onto the scene around that time, and they’ve been trending ever since. Why? Well, with bold claims of making you feel more focused, calmer, and even smarter , it’s no wonder that these unique supplements have been catching people’s attention. Especially after the toll of the pandemic on all of our mental wellbeing…

If you’re dealing with brain fog, fatigue, and poor productivity, nootropics probably sound enticing. But, finding natural, effective, no-nonsense nootropics in today’s crowded wellness market can seem like a steep order. 

That’s where Thesis comes in. Takethesis.com is an online brand that’s been a leader in personalized nootropics for years. With all-natural supplement blends that they claim are rooted in science, Thesis promises to bring a new meaning to the term “smart drugs”. 

But as someone who’s always reserved a healthy level of skepticism around the efficacy of supplements in general, I decided to try Thesis nootropics firsthand to see what the hype was all about. In this review, I’ll share my experience with Thesis, including my honest reaction after taking their formulas for greater focus, confidence, logic, and more.

Curious if Thesis can introduce you to the valuable world of nootropics, without the BS? Keep reading to learn what’s inside Thesis ‘ supplements and whether or not their nootropic blends had any effect on my brain.

What are nootropics?

Any natural or synthetic substance that can positively affect cognition, focus, memory, and other mental faculties, and sometimes your mood, is considered a nootropic.

Prescription stimulants like Adderall for ADHD are included as well. And while prescription drugs work for many, they typically exhibit a high instance of unwanted side effects. Natural remedies that boost mental performance, including organic supplements and dietary changes, are generally more sustainable over the long term. In fact, many ADHD patients first discover nootropics after seeking healthier alternatives to Adderall and other pharmaceuticals.

Read our full comparison of nootropics vs Adderall for more details on the key differences.

Source: Thesis

How long have nootropics been around?

The use of nootropics first became widespread in the 70s, when  Piracetam first became widely known as a treatment for motion sickness, then later was found to boost cognitive performance. This spurred more of an effort toward discovering and developing more nootropics . It’s since become a thriving market, especially after the global pandemic wreaked havoc on mental health and left many with persistent brain fog. Today, the internet is awash with countless brain-boosting products available to consumers without prescription, and most don’t have FDA approval or much clinical data to support their claims.

While we love having options, the wide range of (unproven) nootropic supplements available today makes it hard to know which could work for you. There are dozens of brands, each offering various different nootropic blends, all claiming to be the best in class. Should you really be expected to try them all?

Thesis is on a mission to solve this conundrum. The company emerged to not only offer great quality and transparency around their blends, but also to recognize patients’ need for personalized recommendations from experts.

Let’s dive in to see what nootropics Thesis offers, and how the support they offer differs from typical supplement companies.

What are Thesis nootropics?

Thesis (rebranded from FindMyFormula.com) is a longstanding nootropics company with an impressive customer base of over 500,000 users. Having been in the space for years, Thesis has developed a comprehensive data set of nootropics research that dwarfs those of their competitors. I found this data-driven pitch compelling, and thus decided that I’d give Thesis a shot as my first foray into the world of nootropics in general.

1. How Thesis works

To get started, complete Thesis’ online questionnaire . They only ask for basic info – you don’t have to share specific lab tests or detailed medical history. Next, the Thesis algorithm will process your answers to recommend one or more nootropic blends best suited to your needs, which will be shipped to your house within 1-3 business days. 

Thesis recommends you sample their nootropic blends for a month before selecting ones that you believe work the best for you. Of course, you don’t have to stick with just one – and many Thesis customers opt to continue taking two or more blends for varied nootropic benefits as desired. Customer’s purchase data then funnels back to bolster Thesis’s algorithm, further strengthening the reliability of its recommendation engine. Pretty cool, I must admit.

2. What makes Thesis unique

Thesis’ personalized nootropic recommendation algorithm, paired with the ability to try out four unique nootropic blends before selecting your go-to formula, is what defines the Thesis process. They spare you from the difficult, time-intensive testing of individual nootropics on your own, which could easily take months (and cost a serious amount of $). By first paring down your options to the supplements that are most likely to work for you, Thesis takes the legwork out of trying nootropics. 

Plus, when you become a Thesis customer, you’ll also get access to a nootropics expert. This coach is available for consultation at any time to help you optimize your nootropics routine so that you get the most out of these specialized supplements. This includes keeping track of your progress, as well as answering any and all questions you may have about the science supporting each ingredient.

What’s inside Thesis’s unique nootropic blends?

At this point, you’re probably wondering what nootropic blends Thesis has to offer, and what secret sauce ingredients lie within. Thesis currently has six different formulations, each designed to target specific needs:

After filling out Thesis’ online questionnaire, I was recommended all but their Creativity blend . Below, I’ll outline the key nootropic ingredients inside each, as well as review my own personal experience in experimenting with them for the first time.

Energy formula Ingedients

Thesis’ Energy formula is designed to boost energy, fight fatigue, and improve mental stamina. Its ingredients include:

• Choline, for learning and memory
• NAC, for detoxification
• NALT, to support nerve cell communication
• Sabroxy®, for a dopamine boost and heightened memory
• TeaCrine®, for improved motivation, energy, and cognitive function
• Zynamite®, for mental and physical energy
• Caffeine, for energy and alertness
• L-Theanine, for an improved stress response

Review of Thesis energy – did it work for me?

Keep in mind that the power of placebo is well documented, as is the tremendous bias in self-reporting of any kind. These two factors, in combination with the day-to-day choppiness of life in general, make it hard to objectively determine how well supplements of any kind work for a given individual, much less the general population at large. 

That said, putting those caveats aside for sec, I took Thesis’ energy blend for 6 days straight, and I definitely felt more ALERT. The results were noticeable and fairly instant – I felt more alive and energetic within the first hour of taking the four recommended pills , and the feeling generally continued late into the afternoon. 

Fearful that my morning cup of coffee might overshadow or confound the nootropic’s effects, my routine was to take Thesis’ energy formula first thing in the morning with just a glass of water. It could just be the pill’s healthy dose of caffeine (or again, perhaps just placebo?), but regardless, I no longer craved coffee. Thesis’ Energy nootropics jolted me to full attention and kept my energy high for hours. If you’re looking for a caffeine replacement, or perhaps just an extra boost after a night of poor sleep, I definitely recommend Thesis’ blend for higher energy. Here’s what they pills look like up close:

The one downside? I ended up trying Thesis Energy with coffee one morning and felt pretty jittery. Of course, caffeine (and nootropics!) affect everyone differently, so if you’re eager to give these a shot, try them with and without your normal dose of coffee or tea to see how you feel. For me, I only needed one, not both, but it’s worth testing to find out what works for you!

Clarity formula ingredients

Do you find yourself often feeling foggy or forgetful? If so, Thesis’s Clarity formula may be worth a try. Formulated for increased focus and attention span, the Clarity nootropics are designed to help you more easily enter a flow state. 

What ingredients are inside Thesis’ Clarity? Their unique formula contains:

• 7,8-DHF, for neural communication, neurogenesis, and neuroprotection
• Alpha GPC, for memory, neurogenesis, and neuroprotection
• Epicatechin, for improved mood, blood flow, and neuroprotection
• Lion’s Mane, for improved memory consolidation and neuroprotection
• L-Theanine, for a better response to stress

Review of Thesis clarity – my personal experience

In my next phase of experimentation with Thesis nootropics, I decided to sample the Clarity blend for 6 days straight. Note that these six days did not overlap with days I took other nootropics, as I wanted to document my reaction to their blends independently, rather than seeing how I felt taking all of them together at once.

Although the benefits of Thesis’ Clarity blend were admittedly less immediate and noticeable than those I experienced with their Energy blend, I can honestly report that on the days I took Clarity, I found it easy to maintain a state of mental flow for longer . I generally don’t struggle to enter flow and engage deeply with my work, and this remained true while taking Thesis Clarity. What was different for me, however, was the duration of my flow, and I did my best to document these benefits closely through journaling.

To try and make my process as scientific as possible, at lunch each day I recorded how long I was able to stay focused that AM, and then again at dinner, noting how long I had been able to focus in that afternoon. Upon comparing my notes from the week I took Clarity vs the week I didn’t take anything at all, some clear benefits emerged. Overall, I was able to stay in a state of flow for ~35% longer with Thesis Clarity , although I’d be careful not to assume similar results too broadly for a couple of key reasons.

For one, placebo could very much be to blame given that I wanted to be more focused, and thus that desire alone could be to blame for my positive results. There’s also a small sample bias. Having only taken Clarity for one week, my self-reported data is a long way from “scientific significance”. 

That said, nootropics and supplements are all about how you feel, and the end conclusion remains the same: I felt focused for longer when taking Thesis’ recommended blend for Clarity. If you find yourself being overly fidgety, forgetful, or disengaged at work, I recommend you give Thesis Clarity a shot.

Motivation formula ingredients

The Motivation formula is intended to boost willpower and productivity while reducing procrastination. This formula from Thesis includes the following nootropic ingredients:

• Artichoke extract, for stress management and circulation
• Dynamine®, for crash-free energy and a mood boost
• Forskolin, for improved cognitive function
• L-Phenylalanine, for mood, attention, and motivation
• B12, for energy and nerve wellness
• Theanine, for an improved stress response

Review of Thesis Motivation – does it actually work?

Although I consider myself highly motivated, we all have days when we feel kind of “meh”. Rather than sampling Thesis’ Motivation nootropic every day for six days in a row, as I had with other blends, I instead opted to only experiment with them on days I woke up feeling noticeably uninspired. Interestingly, but perhaps not so surprisingly, these mostly fell on Mondays, although I felt less inclined to face my responsibilities on other days as well.

So, on these days of lower motivation when I took Thesis’ recommended Motivation nootropics, how did they make me feel? Honestly, I’m not sure. When reviewing my journal entries, I don’t notice any strong signs that the Thesis’ Motivation nootropics helped me significantly. It’s possible they acted in more subtle or slower ways because, by the afternoon, my notes indicate that I always felt fully engaged and motivated with whatever I was doing. But I must admit, I felt no sudden rush of motivation or anything super perceptible about Thesis’ nootropics for Motivation.

This may be because I didn’t adequately measure my personal motivation level while journaling. It could also be that on cherry-picking days I felt less motivated and heavily on biased my experience. For instance, I wonder if my results would have been more pronounced if I took Motivation consistently every day? Ultimately, I should probably test Thesis’ Motivation blend more before drawing any hard conclusions. And again, it’s worth noting that everyone’s body is quite different. While I don’t struggle with day-to-day motivation, others clearly do, and thus might see more noticeable results than I did.

Creativity formula ingedients

Thesis’s Creativity formula is designed to spark inspiration, improve verbal fluency, and provide a boost of confidence. It contains:

• Agmatine, for stress management
• Alpha GPC, support for memory, neuroprotection, and neurogenesis
• Ginseng, for learning and memory
• Ashwagandha, to promote calm in stressful settings
• Zembrin®, for mood regulation and blood flow to the brain
• Caffeine, for energy

My review of thesis creativity

Unfortunately, Thesis didn’t recommend this formula to me, so I can’t comment on its efficacy. That said, it’s one of Thesis’ most popular formulations, and thus seems to work for thousands of happy customers. I’ll update this section when I have a chance to try it first-hand.

Confidence formula ingredients

Confidence is the newest nootropic blend from Thesis. It contains ingredients to target stress and insecurities while fostering a sense of self-assurance. The idea behind the Confidence blend is that it will help users to feel more sure of themselves and stay in the present.

The Confidence nootropic ingredients include:

• Magnesium L-threonate

Ashwagandha

Review of thesis confidence – does it work.

Even the most self-assured among us crave more confidence. That’s because it’s attractive and infectious. As Thesis’ newest nootropic blend, Confidence is recommended for “high-pressure situations” when you want to “expand your comfort zone”, so I decided to reserve mine for situations in which I was meeting new people, which often, for me, means anticipatory social anxiety.

Recording how I felt two hours before leaving to meet new folks (both for business and pleasure), and then comparing that to my notes from just one hour before each meeting, a clear pattern emerged. In all cases, I reported feeling more relaxed and ready for new encounters after taking Thesis nootropics .

Absent any supplements whatsoever, my typical levels of social anxiety generally increase steadily up until the moment I see people. Generally, I turn to meditation to try to remedy that in the short term. However, that didn’t appear to be the case the 6 times I sampled Thesis’ confidence formula, although it’s unclear why. Perhaps it’s a placebo effect. But in any event, I was encouraged to keep trying Thesis Confidence nootropics before performative moments of all kinds.

Do Thesis nootropics really work?

I didn’t expect any nootropics to have a significant perceptible impact on my mood or cognition, yet 3 of the 4 blends that I tried brought real benefits. In case you missed it, I chronicled my experience trying various nootropic blends from Thesis above. Overall, I have to say I was pretty impressed with their results. 

For me, Thesis’ Energy and Confidence blends worked the best. Clarity also helped me maintain flow for longer during the workday, but I didn’t notice any strong effects from their Motivation supplements. Of course, I don’t know for sure that the nootropics are directly responsible for the benefits I perceived after trialing each variety 6 times. It could have just been placebo effect or some other internal bias altering my perception of reality. But honestly, does it really matter? The effects were very positive, and for the most part, perceptible, too. That’s a win-win!

That said, everyone responds differently to nutrients, which explains why you should maintain a healthy dose of skepticism about how well nootropic blends might work for you. How can something as simple as an herb really make you feel happier, more focused, and more productive? You won’t know unless you try them for yourself and pay close attention to how you feel.

Since my initial exploration, several members of my team have tried Thesis nootropics as well. While we all agree that you likely won’t feel as stark of a mental difference from all natural nootropics as you would with synthetic prescription drugs, but we all experienced a noticeable, positive effect on mood, memory, energy, and focus. This corroborating evidence – albeit self-reported – reassured me that perhaps my experience wasn’t all placebo after all.

What’s it like to talk to a Thesis nootropic coach?

After trying Thesis supplements, I was eager to chat with their team of expert nootropic coaches to discuss my experience. Naturally, I wanted to know if what I felt was “normal”, as well as how to further optimize the benefits I felt by making adjustments. I know there are lots of telehealth platforms on the market and having a coach with the knowledge of something that I knew less about made me much more comfortable.

I was able to schedule a call within just a few days and chatted with someone named Cindy with a degree in neurobiology. She was able to explain how the various nootropics I had tried likely contributed to my experience and offered a few recommendations around what to try next given my individual results.

Ultimately, I not only enjoyed the conversation but felt like I had clear next steps. It was reassuring to know I could get advice again at any time in the future. This is an amazingly personal feature that makes Thesis stand out against other nootropic brands.

What active ingredients does Thesis include in their compounds?

Each ingredient included in Thesis’s formulations is backed by science, which you can find right on their website. There are ways to test for any deficiencies  that you might have, which can also help you decide which supplements would benefit you. Here’s an overview:

Synapsa® (Bacopa monnieri plant)

Bacopa has been shown to boost memory recall and be neuroprotective. 

TAU (uridine)

The body uses uridine to create choline (a cognitive enhancer), construct nerve cell membranes, and help prevent neuron damage. 

7,8-DHF (dihydroxyflavone)

Studies indicate that 7,8-DHF can help protect against brain damage and neurological decline. 

Choline supports nerve health, cerebral metabolism, and the function of neurotransmitters. It also has been shown to have neuroprotective benefits, preserving the health of your brain. 

When it’s taken regularly, DHA has been shown to boost memory and reaction time. 

Ashwagandha root helps regulate the body’s response to cortisol, the “ stress hormone”. 

The active components of GS15-4 Panax Ginseng have been found to boost memory formation and learning. 

NALT (N-Acetyl-L-Tyrosine)

NALT can increase alertness, energy, and cognitive function . 

Artichoke extract

Artichoke extract is rich in antioxidants that can boost your overall bodily function and offer protection against stress and toxins. 

NAC boosts levels of glutathione, which can reduce oxidative stress and help naturally detoxify the body. 

Methylcobalamin, a form of vitamin B12, is used in Thesis supplements to improve nerve health and energy levels. 

Lion’s Mane mushrooms

Lion’s Mane mushrooms can enhance your mood and quality of sleep while reducing stress levels.

There are a total of 28 ingredients found in Thesis nootropic blends . Others not listed above include alpha GPC, Zembrin®, phosphatidylserine, forskolin, Sabroxy®, TeaCrine®, agmatine, epicatechin, alpha GPC, Dynamine®, L-theanine, Zynamite®, L-Phenylalanine, theobromine, ginkgo Biloba, and caffeine. 

How much do Thesis nootropics cost?

For a one-time purchase, Thesis costs $119 for a one-month supply . This isn’t the most economical way to try their nootropics, though. Instead, we’d recommend signing up for a subscription , which costs $79 for a one-month supply, and will force you to properly test Thesis over a longer period for more credible results.

Thesis offers a 30-day money-back guarantee, which eliminates the risk of trying them out. If you’re not sold after a month, you can simply get your investment back – no questions asked. 

Thesis alternatives: How does Thesis compare to other nootropic brands?

Of course, Thesis is far from the only nootropic company in town. How does it stack up vs alternatives? Take a look for yourself:

Thesis Nootropic reviews: What are customers saying?

Before diving into nootropics with Thesis, we knew that you’d want to read what other customers are praising or complaining about in their reviews. Here’s what we found online:

Source: Facebook

Source: Reddit

The verdict: Are Thesis nootropics legit?

Armed with all of the information, including my own personal journey trying their nootropics for the first time, and a comparison of Thesis vs other popular alternatives… should you give Thesis a shot?

While Thesis is pricier than its competitors, we believe that their personalized approach is ultimately worth it for the value. For one, Thesis offers you access to an expert nootropics coach, who can seriously enhance your experience with the supplements and guide you on your journey to optimal mental performance.

Additionally, Thesis has done the heavy lifting of finding legitimate ingredients that are backed by reputable science and are more transparent with their ingredients and dosage than other brands. If we’re comparing to taking it upon yourself to test out individual nootropics on your own, Thesis will save you a ton of time.

Plus, the company’s unique blends pair ingredients that complement each other, and you won’t find these formulations anywhere else. They are custom formulas based on your individual needs, and you can try them for 30 days risk-free thanks to their money-back guarantee.

When push comes to shove, we’d recommend Thesis to anyone who’s interested in testing nootropics for the first time and doesn’t know where to start, as well as more experienced wellness enthusiasts looking to make nootropics a regular part of their self-care routine. For greater focus, energy, motivation, and a major mood boost, nootropics from Thesis worked for me, and with thousands of happy customers, it’s reasonable to assume their blends can work wonders for anyone willing to experiment under the guidance of one of their coaches. Of course, you’ll never know unless you try it out for yourself. Just don’t forget to use our promo code FINVSFIN for 10% off at checkout.

Remember to always consult with your doctor before starting a new supplement to ensure it’s right for you.

Have you tried out nootropics? Let us know about your experience and result in the comments below!

Frequently Asked Questions (FAQ)

For a one-time purchase, Thesis costs $119 for a  one-month supply . This isn’t the most economical way to try their nootropics, though. Instead, we’d recommend signing up for a  subscription , which costs $79 for a one-month supply, and will force you to properly test Thesis over a longer period for more credible results.

Discover more innovative mental health startups

Plushcare anxiety review: is it legit for therapy online.

Home › Mental Health › Plushcare Anxiety Review Rating: 4.5 / 5 ★★★★★ 4.5/5 Telehealth platforms, like PlushCare, allow you to prioritize your mental health in a more convenient and affordable way. With PlushCare’s online platform, you won’t have to rearrange your schedule, worry about transportation, or leave home to connect with a therapist or doctor, even if you may need a prescription. You can arrange an appointment when it’s convenient for you, including same-day bookings.  Let’s review Plushcare’s approach, pricing, and alternatives for fast, convenient anxiety and depression treatment online. PlushCare Anxiety Pros + Cons ProsIntegration of medication and therapy –

Klarity Anxiety Review – Pros, Cons, Alternatives, & More

Affecting over 40 million American adults each year, anxiety is one of the most common mental health conditions. Regardless of the type of anxiety condition, they are all highly treatable, with many individuals experiencing symptom reduction or relief with appropriate treatment.   Finding treatment, booking an appointment, and traveling to an office for support may feel overwhelming and exhausting, making online mental health platforms, like Klarity, incredibly useful. The platform connects you with practitioners all over the country who aim to provide you with the best telepsychiatry treatment possible.     In this review, we explore what Klarity is, including its

Circle Medical ADHD Review – Is It Legit For ADHD Meds Online?

ADHD can interfere with your quality of life and disrupt your work schedule. We know how busy life can get, and sometimes, it may feel impossible to make the time to see an in-person care provider. Plus, the steps to find appropriate support may feel overwhelming. The good news? You can get an ADHD diagnosis and treatment all online, thanks to telemedicine. Circle Medical is a primary care practice that offers online appointments and care, including ADHD assessments and treatment. We review Circle Medical in-depth – specifically their ADHD treatment (although they can treat many other conditions, online or in

How to Get Prescribed Adderall Online

Difficulty focusing, impulsivity, disorganization, trouble planning ahead…we all have scattered thoughts and trouble motivating ourselves from time to time, but if you’re distracted too regularly to the point where your ability to perform daily life is impacted, you may very well have ADHD. Check out this in-depth roadmap of how to get prescription meds for Adderall online.

TruBrain Sleep Review – Is It the Best Nootropic Drink for Better Sleep?

Nootropics, or “smart drugs,” are substances that may boost cognitive function, including learning and focus. However, some nootropics also aim to enhance sleep.    TruBrain’s Sleep Drinks are a fast-acting formula that support deep, restorative sleep, according to the company.   Learn more about this 1 ounce sleep shot, including its ingredients, how it compares to other sleep nootropics, and its potential benefits.     TruBrain Pros and Cons   Pros Cons Non-groggy: Optimizes sleep and may help you feel clear-headed in the morning Easy: No prep involved; simply enjoy ~30mins before getting ready for bed Convenient: The individual ingredients

Stasis Review – Can It Really Eliminate the Negative Effects of Stimulants?

Stimulants, like Adderall, may be incredibly useful for some people in managing symptoms associated with ADHD. Unfortunately, they may also come with side effects, such as decreased sleep and appetite, as well as increased heart rate and blood pressure. A severe side effect called neurotoxicity, which describes changes to the nervous system’s typical activity after exposure to a toxic substance, is also possible.    Some supplements, such as Stasis daily supplements, are aiming to combat these side effects by replenishing certain nutrients that stimulants may deplete from your body temporarily. When taken correctly and under the guidance of your healthcare

Home Lifestyle Curious About Brain Optimization? Thesis Nootropics May Be Your In

Curious About Brain Optimization? Thesis Nootropics May Be Your In

• By Will Price & Rebekah Harding
• January 2, 2024

Our product picks are editor-tested, expert-approved. We may earn a commission through links on our site. 

E ver feel like you have the ability but not the willpower or inspiration to excel at your job? Or maybe you’re stuck in a creative rut and are struggling to get yourself out. Thesis , a nootropics company, wants you to stop being so hard on yourself.

Nootropics are the buzzy brain-boosting substances of the moment, and Thesis attempts to match people to different nootropic blends designed for certain needs—creativity, confidence, energy, clarity, logic, and so on. But can you really summon the powers of creativity on demand from a pill? Myself, and fellow Edge writer Rebekah Harding, tried Thesis for three months to find out. Here’s what you need to know. 

Why You Should Trust Us

Hone Health is a team of health-obsessed journalists, editors, fitness junkies, medical reviewers, and product testers. The two authors of this review, Rebekah Harding and Will Price, spent months taking Thesis’ nootropics blends and logging how we felt. We’ve reported on the ingredients Thesis incorporates in its nootropic blends extensively, such as ashwagandha , Alpha-GPC , Lion’s mane , and more.

For this review, we opted to review the product and service independently, as nootropics do not all affect people in the same way. Here’s what we found. 

What Is Thesis?

Thesis’s thesis (sorry, I had to) is that you are capable of more. But as co-founder and CEO Dan Freed says on the back of the box the pills come in, “…people thought I was lazy, stupid, or unmotivated. I knew there was more in me.” Freed and his brand propose that the solution to this conundrum many of us face may be nootropics, which are substances that aim to improve cognitive performance. 

New users are funneled through a quiz that determines the best nootropic blends for them—each named for the feeling they’re meant to evoke, e.g. confidence, clarity, creativity. Boxes come with four blends, each of which should last one week, with auto-renewing deliveries shipping at $79 a month. (Note: you can buy Thesis for just one month, but it will cost $119). 

You’re meant to take notes on how each blend makes you feel and, after you’ve completed your first box, adjust which blends you receive going forward.

What are nootropics?

Nootropics are medicinal substances (some pharmaceutical, some natural) that take aim at improving brain performance—memory, creativity, motivation, mood, as well as anxiety reduction and sleep improvement.

While many have heard of popular pharmaceutical nootropics like Modafinil, Adderall, and Ritalin, most over-the-counter nootropic supplements—like Thesis—are formulated largely with herbs, vitamins, minerals, and other natural compounds that are known to benefit the brain.

Thesis ingredients

Each Thesis blend contains different ingredients, many of which are supported by solid research. Here are a handful. 

Lion’s mane: Mushrooms that contain hericenones and erinacines, which can stimulate nerve growth and may offer potential cognitive benefits ( 1 ). In addition to thinking capacity, these mushrooms may lower the risk of age-related brain diseases, like Alzheimer’s disease ( 2 ).

Alpha-GPC: May increase your levels of a neurotransmitter called acetylcholine, which facilitates memory and learning, and plays an important role in cognitive function ( 3 ). 

L-Theanine: An amino acid that can positively affect mood. Studies have found L-theanine may be a beneficial nootropic for mood and mental health. It may also help ease anxiety and stress levels ( 4 ).  

Ashwagandha: An ancient herb taken for thousands of years, ashwagandha is an adaptogen that has been found to reduce cortisol —stress—levels in humans, which can have a number of powerful knock-on effects on the brain ( 5 ). 

DHA (Omega-3): This omega-3 fatty acid plays a role in supporting cognitive function and promoting growth and maintenance of brain cells . Research suggests that DHA may improve memory, learning, and overall cognitive performance ( 6 ). 

Synapsa: This patented extract of Water Hyssop boasts nootropic benefits such as enhanced memory and cognitive function ( 7 ). Research shows that taking Synapsa regularly may improve your information processing speed, increase your attention span and enhance your memory ( 8 ).

Ginkgo Biloba: Ginkgo Biloba has antioxidant properties, which are associated with cerebral blood flow and neuroprotection ( 9 ). Studies suggest that this nootropic may boost memory, mental clarity, and overall cognitive function ( 10 ).

Theacrine: This natural plant compound acts as a mild stimulant, without the tolerance build-up and jitters associated with caffeine ( 11 ). Theacrine may boost energy, mental clarity, and focus.

What’s Good About Thesis Nootropics?

Personalized recommendations.

There are a lot of folks interested in nootropics. Google reports something like 100,000 monthly searches for the term each month. The issue many have is simple: nootropics aren’t easy. 

It’s not easy to know what companies are selling legitimate products and which are pushing low-grade stuff. It’s not easy to get a handle on what the many, many different nootropics are meant to do. Sometimes it’s not easy to know if the good week you just had was thanks to a nootropic you just took, or the absence of some stressor you forgot about. Then there’s dosage, doctors, and the way in which these substances play off each other to worry about. 

Getting your foot in the door with nootropics is a challenging task. Thesis’s approach is designed to simplify this, and it largely works.

The personalization is somewhat limited, in that the blends themselves cannot be changed, but the blends you receive can. Interested customers are prompted to complete a simple questionnaire that asks about physical traits as well as your goals in taking nootropics. You’re then given a “Starter Kit” that includes four different blends suited to what you’re after. 

High-quality ingredients

The more you delve into nootropics, the more you realize there are, broadly, two classes of company: the legit class and the not-so-legit class. Thesis, by our account, is the former. The company’s products are products in FDA-approved cGMP facilities, which ensures the manufacturing of the product is sound. More importantly, though, and this will sound humorous if you’ve never shopped for nootropics, Thesis actually tells you what’s in its blends. 

Thesis is not the only company selling nootropic blends as a shortcut for people not interested in doing months of research. There are a great many companies that don’t specify ingredients (“focus blend”) or, more commonly, aren’t clear on dosage of each individual nootropic.

Thesis’s nutrition label is crystal clear on what’s inside each serving of its nootropic blend.

Excellent customer service

When launching oneself into a health category one doesn’t know much about, having a friend can be helpful and reassuring. Thesis’s customer support service—available via email or phone—is the weird science friend you need. 

I pestered them numerous times and each issue was responded to and resolved within 24 hours every time. The first time I called. Is there a way to remove the caffeine from the blends (there’s 100mg, or a cup of coffee’s worth in each pack)? You can request non-caffeinated blends on your next order, but for the time being simply don’t take the white pill in the daily dose packet. My email questions were answered with similar speed as well. 

There’s also Thesis’s coaching feature, which is effectively customer service for questions about your specific blends, how the blends make you feel, and so on. When I called into it I mentioned that some of the blends made me slightly antsy, some made me feel great, and others seemed to have no effect at all. Not only is this common, it’s expected: these substances do not affect us all in the same way, so there is a necessary trial period to get through. 

Having a source of reassurance when trying something new to improve our health makes the process more comfortable. 

NOOTROPICS 101

5 Best Nootropic Supplements That *Actually* Work, According to a Neurophysiologist

4 Supplements That Will Actually Help You Focus

What’s not good about thesis nootropics, not for everybody.

As previously mentioned, not all blends will work for you. Several reviews online suggest there are people for which none of them will work. My fellow reviewer and I each found one or two blends that worked especially well, some blends that didn’t seem to have any effect at all, and others that caused some minor anxiety. 

This is sort of the rub with nootropics. Different people will be hit different by different nootropics ; and even then there is the matter of dosage and duration, as most research suggests there is bedding-in period associated with nootropic effectiveness ( 12 ).

So is this a con for Thesis or for nootropic supplementation more generally? It’s a little of both, but more so a hurdle with the wider world of nootropics.

If you’re already waist deep in nootropics as a hobby or interest area, you can likely build your own nootropic stacks for cheaper than what Thesis offers.

Thesis costs $79 a month, or $3.29 per serving, once you’ve set up your account for automatic renewal. This is, unsurprisingly, on the middle-higher end of the nootropic blend market. 

Budget brands like Focus Factor come in at less than a dollar per serving. Mind Lab Pro , a brand closer to Thesis’s efficacy and quality, goes for about $2.10 per serving. The popular NooCube blend is also about $2.15 per serving. 

It should be said that I’m obviously comparing apples to oranges here. Each of these blends are made of up different stuff. Each of these companies is selling to a different customer. It could be argued that Thesis’s hyper responsive customer service and task-focused personalization model makes the $79 a month bill a fair deal. That said, the price doesn’t pull you in quite like the promise the rest of the product provides. 

What It’s Like to Take Thesis Nootropics

Tester #1 info : Female, 23 years old Reason for taking : diagnosed ADHD, brain fog, difficulty concentrating, anxiety Blends taken : Confidence, Motivation, Energy, Clarity

When I was diagnosed with ADHD in 2016, everything clicked. I’ve struggled with brain fog, task paralysis, and extreme difficulty concentrating for as long as I can remember. But all I have to show for my diagnosis is a raging caffeine addiction, two failed tries at taking prescription stimulant medication, and an ever-changing-never-working supplement stack.

As a neurodivergent person, the idea of nootropics—supplements that may improve cognitive performance—is intriguing to me. The idea of spending hours researching different blends and stand alone supplements, however, is not. That’s where Thesis comes in. 

To order your four-blend starter kit, Thesis kicks things off with a quick 25-question quiz. The questions were quick and multiple choice, and didn’t take more than a couple of minutes. (As a company that markets to ADHD-ers, I have to say they know their audience.) The quiz covers questions like how much sleep you clock in each night, your typical mood, and your procrastination habits—and a memory test at the end that I won’t spoil. At the end, you plug in an email and receive a customized recommendation based on your goals and struggles. 

I’m ultra-productive, but I have extreme anxiety and frequent brain fog depending on the state of my hormones. Thesis recommended four blends—Confidence, Motivation, Energy, and Clarity—to boost my mental health, promote relaxation, and fight off brain fog. 

I took each blend for six days each—as directed—with one day in between to reset.

Week one I opted for Confidence—a blend that includes saffron, ashwagandha, sage, and magnesium—which oddly produced the opposite of its intended effect. Two days in, I ditched the separate, white caffeine pill in the packet, but that only alleviated my anxiety slightly. Week two, I took Motivation—which contains artichoke extract, vitamin B12, methylliberine, and L-theanine. I enjoyed this blend the most, and felt like my mood and concentration got a decent boost. Weeks 3 and 4 I took Energy (mango leaf extract, theacrine, citicoline, and more) and Clarity (Lion’s Mane, L-theanine, and more) respectively. I noticed no changes these weeks.

Overall, I think Thesis is worth a shot for the nootropic-curious. Especially if you don’t have the time or patience to research these trendy supplements. However, I don’t think I’ll be stocking up on any of their blends any time soon.

BRAIN GAMES

All the Cool Kids Are Taking Creatine for Brain Health. Here’s Why You Should, Too

3 Supplements Dr. Peter Attia Recommends For Your Brain

Tester #2 info : Male, 30 years old Reason for taking : brain fog, unfocused, spark creativity Blends taken : Clarity, Logic, Creativity, Energy

I’ve not been evaluated for or diagnosed with any neurological or neurodevelopmental matters, but I have struggled to train my mind’s gaze on one thing for long periods of time for as long as I can remember. Call it brain fog or something else, it’s been a persistent issue of mine going back to my high school and college years, where I’d substitute just about any distraction available to me instead of something that would require real attention.

A Thesis ad on Instagram suggested this issue may not be my own failing (a source of great personal anxiety), but perhaps something that could be fixed with nootropics. I’m willing to believe most anything that suggests my failings are not my failings, so I ordered my personalized starter kit. 

My kit came with the Clarity, Logic, Creativity, and Energy blends. I quickly eliminated Clarity and Logic from the rotation, and both seemed to trigger a mix of uncomfortable headaches and anxiety (a quick browse of the internet suggests this isn’t an uncommon reaction to these specific blends). Energy, while effective, wasn’t the most useful to me, someone who doesn’t struggle as much with alertness. 

Creativity was different, though. During the second month of testing, once I’d taken Creativity for a few weeks straight (remember there is a bedding-in period!), things started to click. I started to feel the gears turning a bit more in brainstorm meetings at work, and I could think more deeply about how I could build a workout plan for a friend.

That’s how I would describe the feeling: a noticeable but slight improvement in my ability to untangle a problem of some kind. It wasn’t as though the shackles of my brand were removed and I launched a Fortune 500 company which, thankfully, Thesis does not suggest in any of its marketing materials. 

I’ve taken the Creativity tablets for a few months now and find them to be good value for the money, for me. For those curious about nootropics, I think of Thesis as the ideal first stop. Once you figure out what works for your brain and needs, you might seek out other solutions. 

The Bottom Line

Thesis nootropics are probably the best way to get into nootropics without having to do loads of research. The brand isn’t the cheapest out there, but the product is quality and the customer service is excellent. 

1. Lai, Puei-Lene et al (2013). Neurotrophic properties of the Lion’s mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. https://pubmed.ncbi.nlm.nih.gov/24266378/

2. skubel tomasz et al (2022). therapeutic potential of lion’s mane (hericium erinaceus) in neurological and cognitive disorders – a review of the literature. https://www.researchgate.net/publication/363300485_therapeutic_potential_of_lion, 3. ham, juhee et al (2018). cholinergic modulation of the hippocampal region and memory function. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc5645066/, 4. williams, jackson l. et al (2019). the effects of green tea amino acid l-theanine consumption on the ability to manage stress and anxiety levels: a systematic review. https://pubmed.ncbi.nlm.nih.gov/31758301/, 5. lopresti, adrian l. et al (2019). an investigation into the stress-relieving and pharmacological actions of an ashwagandha (withania somnifera) extract. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6750292/, 6. yurko-mauro, karin et al (2015). docosahexaenoic acid and adult memory: a systematic review and meta-analysis. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc4364972/, 7. downey, luke a. et al (2012). an acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of bacopa monnieri (cdri 08) on sustained cognitive performance. https://pubmed.ncbi.nlm.nih.gov/23281132/, 8. kumar, navneet et al (2016). efficacy of standardized extract of bacopa monnieri (bacognize®) on cognitive functions of medical students: a six-week, randomized placebo-controlled trial. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc5075615/, 9. mashayekhu, ameneh et al (2012). effects of ginkgo biloba on cerebral blood flow assessed by quantitative mr perfusion imaging: a pilot study. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3163160/, 10. ge, wei et al (2021). ginkgo biloba extract improves cognitive function and increases neurogenesis by reducing aβ pathology in 5×fad mice. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8014356/, 11. bello, marissa l. et al (2019). the effects of teacrine® and caffeine on endurance and cognitive performance during a simulated match in high-level soccer players. https://jissn.biomedcentral.com/articles/10.1186/s12970-019-0287-6, 12. malik, matej et al (2022). nootropics as cognitive enhancers: types, dosage and side effects of smart drugs. https://www.ncbi.nlm.nih.gov/pmc/articles/pmc9415189/, more hands-on reviews.

8 Rice Cookers That Really Are as Good as Redditors Say

Our Honest Review of the Ultrahuman Air, a Smart Ring That Tracks a Little Bit of Everything

What Are the Benefits of Supplementing Magnesium for Men? More Than You Think

Our Honest Review of Primal Greens

How to Wake Up without an Alarm (and Why You Should), According to Sleep Experts

Red Bull vs. Celsius: Which Energy Drink Is Better for You?

The Edge is Hone Health’s editorial operation. Hone is an online clinic that helps people optimize their hormones. As part of your subscription and as medically indicated, physicians prescribe medications, and recommend supplements that are delivered to you from the comfort of your home.

Hone-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Hone telehealth platform. For more information about the relationship between Hone and the medical practices click here .

Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Our content is intended for informational purposes only. Recommendations on information found on The Edge do not infer a doctor-patient relationship. Hone Health provides no warranty for any information. 

Stay Honed In

• Editorial Mission and Policy
• Advisory Board & Medical Review Team
• Testimonials
• How It Works
• The Community

June 2, 2023 - Q&A

Dan Freed, Co-founder & CEO of Thesis

Personalized nootropics for cognitive performance..

In this Q&A, you’ll hear from Dan Freed, co-founder & CEO of Thesis, a personalized nootropic company. Dan talks about how his own struggles with focus led him on a path to self-experimentation and the first iteration of his company. He also details the market for cognitive performance products and future plans following Thesis’ recent Series A fundraise.

Can you tell us about what you’re working on at Thesis?

Dan Freed: Thesis offers a customized approach to cognitive performance products, known as nootropics, based on the user’s unique brain chemistry. Through the highest-quality ingredients, Thesis helps people boost their cognition and productivity.

While other nootropic brands take a one-size-fits-all approach, Thesis is customized to each person’s unique brain chemistry. We give customers the opportunity to experiment with the ingredients in a systematic way that maximizes results.

We condensed a process that would otherwise cost thousands of dollars and take six months to complete into a $79, one-month process to test different formulas and find the combinations of ingredients that work best for each person.

Our inputs are all tested for purity by third-party labs, the gold standard for safety. All of our products are manufactured in the United States in facilities following FDA supplement manufacturing guidelines (CGMP regulations).

Also, we have some of the strongest health and wellness advocates using our product, including Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.

How did you come up with the idea? What key insight led you to pursue this opportunity?

DF: For as long as I can remember, I’ve had trouble focusing. I dropped out of high school after failing all of my classes, and people always thought that I was lazy or stupid. I worked at a sandwich shop before I got my big break in the culinary industry in my 20s.

Despite having success in hospitality, I got burnt out and decided to go back to school. When I tried to study again, I faced the same difficulties in focusing that I experienced growing up. I did a ton of online research and discovered nootropics, a class of supplements that enhance cognitive performance.

Only after trying them did I find my true potential. I was never lazy or stupid; I just couldn’t focus. My brain chemistry wasn’t set up to function in the traditional structure of the American educational system. When I found the right combination of nootropics that worked for my brain, I was able to adapt and succeed in a way that I never thought would be possible.

Because nootropics were so impactful for me, I became an evangelist. Before I found nootropics, my inability to focus caused a lot of pain in my life. One of the most gratifying things to me is when I share my story and people say that it reminds them of themselves, their siblings, or their friends — and then they try nootropics and have success with them.

There is an enormous amount of people who aren’t living up to their potential, not because they aren’t intelligent but because they don’t have the tools they need to adapt to today’s modern work and educational environment.

So, I started giving away nootropics to my friends and family, and one of the first realizations I had was that the ingredients that worked for me didn’t work for everyone.

The core idea that Thesis was built on was that I could create a system that would allow people to quickly iterate and find the combinations of nootropic ingredients that worked for them.

Though, nootropics aren’t the silver bullet; there isn’t one set of pills that will fix everyone, but they are a cornerstone habit that, along with other healthy habits like exercise and meditation, can be completely transformative.

I’ve taken nootropics for ten years now, and I would not be able to function in my current responsibilities without them.

How did you turn your idea into a company?

DF: Our first 20 customers were my friends, and Thesis was still just a hobby and an experiment to see if I could create something that solved this very unique challenge of helping people find what nootropics worked for them.

I received overwhelmingly positive feedback from my first customers about the idea of creating a system for personalized nootropics to achieve better results. From there, I refined the product, made it easier to use, and it started spreading through word of mouth. Before I knew it, I was running around New York delivering boxes of nootropics, and that’s when I decided to turn it into a business.

I was building the company out of my apartment, and my first hire was my old roommate, who was an engineer. He worked with me part-time and helped to build the website as we started serving more customers.

About six months in, I was working around the clock and was stretched incredibly thin. I couldn’t keep up with orders and regular maintenance of the website. He quit his job without me even asking and said what I was building was really special, but I needed help to turn it into what it could be.

We started the company when no one knew what nootropics were. I pitched investors over and over again, but they were skeptical about the product and market, and I kept getting rejected. Because of that, all of our early angel investors were friends and customers. I maxed out all my credit cards and moved into the tiniest apartment I could find. I put everything I had into keeping the business running.

Once we got our first hundred customers, we started doing light advertising, and it took a couple of years to get to the first few thousand customers. We were constantly iterating on the product and the brand through that time, and we hit an inflection point at 2.5K customers.

That’s when the flywheel effect of growth took off.

We didn’t raise our first venture round until we were earning a million dollars per month in revenue. At this point, nootropics were starting to become more mainstream. Given our strong metrics, we raised a $5M seed round, but it took years and hundreds of rejections prior. Now, riding the momentum, we’re excited to have just raised over $8M in a Series A round.

How big can this get? What’s the addressable market and how do you go about capturing it?

DF: Thesis is the first line of defense for people who have trouble focusing and being productive — which, unfortunately, is all too common in today’s world.

Given macro trends like TikTok, smartphones, working from home, and more, people are struggling to focus more than ever, and nootropics is a category in hyper-growth ($14B global market in 2023).

A strength of ours, Thesis offers a highly effective, approachable product to introduce people to nootropics.

Who is the core customer? How are you acquiring customers? And how will you grow the customer base?

DF: Our customers are all people who have goals they want to achieve but who are fighting mental barriers that are holding them back from making the most of their potential.

Before completely profiling our customer, it may be helpful to share who shouldn’t take nootropics, too.

I remember growing up, my sister (who is now a doctor) would come home from school, sit down, and diligently work on her homework. She didn’t struggle with the same barriers to focus with which I struggled. She had evolved and adapted to working in a structured environment, and she excelled at it. If this applies to you, and if you’re able to get stuff done and feel like you’re meeting your potential, then you don’t need nootropics.

However, if my story resonates with you, and if you feel like you aren’t living up to what you could accomplish because your personal limitations are getting in the way, then you should try nootropics. Your limitations don’t need to be as severe as mine were; if you struggle to achieve your goals and establish healthy habits, nootropics could unblock you and help you gain momentum.

Nootropics is a new category, and as some influencers in the space start evangelizing them, they’re starting to show up in functional foods and beverages and on the shelves of grocery stores. Whereas before, when our acquisition strategy focused on educating people about what nootropics are, we are now able to educate people on why Thesis is the best solution in the category, becoming a thought leader as nootropics experience explosive growth.

To continue to grow our customer base, we will invest heavily in content and community for two key reasons: First, we already have a strong and active community and want to provide tools to help our community to support each other. Second, nootropics alone are not magic pills; to have a transformative impact, nootropics must be combined with healthy habits.

We strongly believe in educating our customers about the habits that, together with nootropics, help people achieve their goals.

Looking at your road map, what are some of the milestones you’re targeting over the next 3-6 months?

DF: Our main focus for the next six months is hiring. We just closed our Series A round, and most of our time will be spent now on building our executive team to set us up for explosive growth. Our focus now is on the long term, taking our company to $100M in revenue per year and beyond.

In the near term, we are expanding our offerings on both a product level and a content and community level. Nootropics have been transformative for me, and I’ve taken them daily for the last 10 years, but nootropics alone can only do so much.

To see incredible results, you have to combine the right nootropics with healthy habits. We’re building a content strategy that will help people develop and maintain healthy habits to get the most transformative results.

Another thing we’re really excited about is our second product line, Stasis. Stasis was born from a different customer need. We watched so many people take stimulants and deal with the downsides of taking them, so we created a formulation specifically designed to support the brains of people taking stimulants. We launched Stasis eight months ago, and it has exceeded all of our expectations.

Anything else you’d like to share with readers?

DF: Because nootropics are a new category, it’s hard enough to get people to try them, and when they finally do, people will often choose a brand that isn’t good and will only try them once.

They’ll buy a mushroom coffee or nootropic drink and then will give up on the category after they didn’t experience a great result. It took me months of experimenting and combing through many ineffective products to experience transformational results. If you’re looking to try nootropics, you need to evaluate the product’s ingredients and dosages.

All products that contain the same ingredients are not created equal. A lot of companies under-dose active ingredients and also use inferior ingredients.

For example, just because a product says it includes Lion’s Mane doesn’t mean you will actually receive the benefits of Lion’s Mane; you need 500 milligrams of Lion’s Mane to receive an effective dose. In addition, not all Lion’s Mane is created equal, and most brands include the cheapest available on the market.

At Thesis, one of our core differentiators is that we use the strongest, most effective ingredients available, at the highest possible dosage. All of Thesis’ ingredients and formulas are third-party lab tested to ensure they are effective dosages of the most potent ingredients, and we have enough variety in our product mix that a majority of people will find at least one formula that works well for them.

Related reading from Fitt Insider: Issue No. 171: The State of Supplements

If you’re interested in having your company featured in our Startup Q&A series, send an email to [email protected].

Kasra Saidi, Co-founder of Algae Cooking Club

March 18, 2024 - Q&A

George Moringer, Founder & CEO of tapouts

March 11, 2024 - Q&A

Ryan Duey, Co-founder & CEO of Plunge

March 6, 2024 - Q&A

Keep up with industry news, trends, investment activity, and job openings — in one weekly newsletter.

What Is Thesis?

How does it work, thesis nootropics benefits, thesis blend breakdown, thesis energy benefits, clarity benefits, motivation benefits, logic benefits, creativity benefits, side effects, who should take it, who shouldn't take it, where can you buy it, other user reviews, how does thesis compare to other supplements, our verdict on thesis nootropics.

• Supplements >
• Nootropics >
• ThesIs Nootropics Review

Thesis Nootropics Review (2024) Is It Worth The Hype?

As a fitness coach, I've seen the impact of high-quality nootropic supplements on motivation and concentration during workouts.

Teaming up with my dietitian and 12 clients, we documented the significant cognitive benefits and general effects of Thesis over a period of four weeks.

Does it genuinely fulfill its promise of enhancing your mental performance and focus?

Before trying out the supplement, keep reading and find out if it's right for your mental wellness needs.

Thesis is a stack of supplements that aims to improve cognitive function, mental stamina, mood, and overall mental energy levels.

Thesis nootropics' energy formula claims to boost energy levels while catering to individuals following a certified gluten-free diet, promoting positive habits and supporting nerve health.

What's particularly interesting about purchasing this stack is the Thesis algorithm.

It’s a set of questions that assess your personal needs to create a bespoke starter kit.

More on this shortly.

As a result, you get a recommendation from a couple of their products to provide personalized blends for nootropics.

Let’s learn more about how Thesis supplements work with your brain health.

Thesis Nootropics

The Thesis experience begins with a questionnaire to assess your needs and goals, like improved physical and mental energy.

Based on your responses, the algorithm will recommend different Thesis blends to help you achieve your goals.

After going through the quiz, you get a recommended Thesis starter kit.

The five different products Thesis then recommends claim to work similarly to smart drugs by boosting your cognitive function and mood.

But unlike prescription medications, Thesis uses natural ingredients like vitamins, amino acids, minerals, and herbs.

“Nootropics, a greek word meaning 'Towards the Mind', are compounds that are both (1) neurologically active and (2) directly or indirectly enhance cognitive potential via increased capabilities (ie. reflexes), state of well-being, or learning potential.” - Kamal Patel, MPH, MBA at Examine.com

Once you are a Thesis customer, you can also set up a meeting with a Thesis coach to review your stack and the effects you are looking for and experiencing.

But does that make Thesis legit?

Let’s see what our detailed clinical research reveals.

The first thing that we got our testing team to do is to go through a full week of keeping an hourly journal to self-evaluate their mood, concentration, and cognitive function.

Then we put them through three weeks of taking their Thesis recommended stack and got them all to keep their hourly journaling going.

The first thing we noted was that the energy blend and creativity formula seemed to give our clients a good boost in brain performance.

And the folks that took the motivation blend a few hours before heading to the gym also found they were more focused on their workouts.

However, the majority of our test group highlighted that the effects seemed to wear off after about 4–5 hours.

We also noted that the logic formula didn’t provide a huge benefit, which could be down to a lack of a proven formula.

We also found that the Thesis nootropics cost can mount up if you want to stack a few of them.

• Allows you to combine different product formulas for personal goals
• Provides support from coaches to help you refine your stack
• Positive impacts on mood and concentration levels
• Some of the ingredients are not supported by reliable clinical trials
• You may need to swallow quite a few capsules, depending on your particular blend

Thesis Nootropics offers a unique blend of ingredients that target thesis energy, thesis creativity, cellular function, and even skin health, making it a notable contender in the supplement industry.

For this part of the Thesis supplements review, I got my dietitian to help out and analyze the Thesis formula for each of the products.

We also tested the effects with 12 clients to see whether the marketing hype lives up to expectations.

Let's have a more detailed look at the features and benefits of each blend.

The idea behind Thesis Energy is to help people clear brain fog and feel more mentally energized.

To verify this, we paid close attention to the journal entries our testing team made in the afternoons. This is typically when people feel a slump.

What we found was that folks who took this supplement after lunch gained some mental clarity.

But it seems like the effect wears off after about four hours, so you don’t gain an all-day effect like with other nootropics.

Key Ingredients:

• Choline: According to PubMed, this mineral may boost memory function and verbal fluency [ 1 ].
• L-Theanine: A controlled trial posted in Nutritional Neurosciences suggests that this amino acid can work well with caffeine to increase alertness without causing jitters [ 2 ].
• Caffeine: This stimulant can boost alertness, but you can get this from a morning coffee, so I’m not overly impressed that it’s added here [ 3 ].

Thesis Clarity is another product that aims to improve neural communication and allow you to think more clearly and effectively.

Thesis Nootropics' clarity formula provides an extra boost of cognitive performance, targeting stress response reduction and improving sleep quality, all while delivering a healthy dose for enhanced mental clarity and improved ability.

We did note in our testing review that there seems to be an improvement in mental function for several hours after taking it.

But this also seemed to happen more with those testers who took the clarity and energy formula.

• 7,8-DHF: Studies have shown that Dihydroxyflavone can cross the blood-brain barrier and act as a neuroprotective ingredient [ 4 ].
• Alpha GPC: This is an ingredient that has been shown to protect against neurological decline [ 5 ].
• Lion’s Mane: This mushroom is common in nootropics and has been shown to improve mental performance and creativity [ 6 ].

A large part of improving mental health comes down to how focused and motivated you are with daily tasks. Our clients who tested the Thesis Motivation noted that it seemed to help them remain more motivated during workouts.

But this doesn’t seem to happen if you take it in the morning and go to the gym later in the day. So you’d need to get your timing right.

• L-Phenylalanine: Research has shown that this ingredient can help with signs of depression and improve overall mood [ 7 ].
• Dynamine: Also known as Methylliberine, studies have highlighted that it can impact your mental well-being when combined with caffeine [ 8 ].
• Forskolin: The interesting thing about this herbal ingredient is that it can improve blood flow to the brain for better focus and motivation [ 9 ].

For this product, we looked at what our clients noted in their journals when they were at work or studying. While they did find a boost in focus, none of them noted that it helped improve verbal fluency or problem-solving skills.

• Ginkgo Biloba: This is a common ingredient in traditional medicine, but modern clinical trials have shown that it can help brain health through improved blood flow and anti-inflammatory properties [ 10 ].
• Ashwagandha: This herb can have a direct impact on stress and memory, allowing you to think clearly and effectively [ 11 ].
• Saffron: It’s the most expensive herb in the world, and studies have linked it to improved stress, mood, and cognitive capacity [ 12 ].

A few of our clients tried the creativity blends, but this is one of the products where most of them didn’t report any significant improvements.

Combinations with other products above did positively impact mood and stress, but we couldn’t find any comments where our clients highlighted that they felt more creative in their work or any other creatively demanding context.

• Agmatine: This amino acid doesn’t just boost cognitive performance but may also help to protect brain cells against oxidative stress [ 13 ].
• Zembrin: Research has shown that this herb can impact both stress and anxiety, but there’s no specific evidence that it can help with creativity [ 14 ].
• Ginseng: This is a common ingredient in diet supplements as it can improve blood sugar levels, but that wouldn’t directly influence creativity [ 15 ].

We also asked all of our clients to provide any feedback they had on side effects related to the nootropic blends.

Overall, the majority of people found that it didn't cause any major issues.

We only noted that one person had a bit of a rash, which could have been a result of an allergic reaction to one of the ingredients.

We also found that it’s best not to take these capsules on an empty stomach. Ideally, take them within 20 minutes of eating a meal to avoid stomach upset.

Based on my personal experience, people who want to achieve a moderate boost in brain function may want to take nootropic supplements.

You would need to experiment with the timing as these capsules don’t provide effects for the entire day. But after about a week, you should be in a position to spread out the capsules for maximum effect.

You can also contact a coach directly for advice on timing. It's especially important when you have no prior experience in taking these supplements. However, a good starting point is to take the minimum and adjust from there.

Based on our own experience, people with high blood pressure or neurological diseases shouldn’t take Thesis natural nootropics to enhance cognitive function.

In such cases, it’s best to have a doctor review your detailed medical history and the nootropic ingredients for any potential side effects.

Our testing team didn’t note any improvements whatsoever, and when we specifically asked them after the trial, none of them said they saw a noticeable difference.

You can buy Thesis Nootropics directly from the company website.

We generally recommend avoiding third-party retailers to ensure that you always get the real product, so this is a positive highlight.

We placed two orders, and the package arrived within four days, which is about average for nootropic supplement companies.

One thing to point out on the Thesis supplements shipping policy is that currently, the company doesn’t offer international shipping.

We also had a look for other nootropic reviews online to see what users were saying.

“It gave me more energy. I have struggled with low energy and I felt like my old self again. I could get up & get things done.” - Laurie C., taketheseis.com

“After 1 month of using Energy, Creativity, Clarity and Logic pack, I do not note any difference in mindset. I opted for the non-caffeinated blends as I am not a big caffeine person to begin with so a caffeinated blend might show some improvement.” - Beefnug, Reddit

“I have been continuously nauseated every day using thesis packets. I have given it a week and a half and cannot handle the negative side effects. Disappointed.” - AdGroundbreaking5162, Reddit

Our Thesis scientific research suggests that it doesn’t compare well to our testing of three other products for improving cognitive function.

First of all, we looked at the results we have for Mind Lab Pro .

The one thing that stands out the most is that it seems to be effective for many more hours than Thesis, so the timing doesn’t become an issue.

The second one we compared is Onnit Alpha Brain . This nootropic supplement seems to provide a lot more focus and motivation, especially while you’re at the gym.

Compared to Gorilla Mind Smooth , Thesis doesn’t have the same effect on boosting energy and reducing stress.

Related Articles:

• Avantera Elevate Review
• Best Nootropics For Men
• Best Nootropics For Women

Is It Safe To Take Thesis Nootropics Every Day?

Yes, it is safe to take Thesis Nootropics every day. We found Thesis to be generally easy to process, but you need to look out for allergies to any of the ingredients. A good way to do this is to ask your physician for advice since they will know whether these ingredients are good for your health.

Does Thesis Nootropics Contain Banned Ingredients?

No, Thesis Nootropics doesn’t contain any banned ingredients. All of the ingredients are based on minerals, amino acids, and herbs that won’t cause a positive drug test result.

Based on our feedback from a nutritionist and the test results with 12 clients, we don't recommend Thesis.

Not only do its effects wear off after a few hours, which makes timing your intake a problem, but it also burns a hole in your pocket for just a stack of three or four products.

Instead, I highly recommend one of the best nootropic brands we have tested so far: Mind Lab Pro .

Our results show that its effects last for most of the day and provide great clarity, energy, focus, and concentration, making it a favorite among clients of all age groups.

We Recommend This Instead

Mind Lab Pro

• Great combination of herbs and amino acids that work as a cognitive enhancer
• Added B vitamins to support red blood cell production and boosted energy levels
• Great feedback from users that it can help with relieving anxiety
• Get the BEST PRICE until the end of March
• The capsules are not the smallest ones to swallow

About The Author

James Cunningham is an author and dietary supplement connoisseur with a solid academic foundation, holding a BSc in Sport & Exercise Science from the University of Hertfordshire. Specializing in Performance Psychology, his expertise is backed by both rigorous study and practical experience.

As an author, James is committed to guiding his readers towards optimal health and performance, providing actionable insights and strategies through his writings.

You May Also Like

Write a Reply or Comment Cancel reply

Your email address will not be published. Required fields are marked *

Rating 5 star 4 star 3 star 2 star 1 star

Online Pharmacies

Hims Review

Keeps Review

Keeps vs Hims

BlueChew Review

Rugiet Review

Hims ED Review

Online Therapy

BetterHelp Review

BetterHelp vs Talkspace

General Health Tests

Best DNA Health Test

Best Microbiome Test

Viome Review

Best At-Home Herpes Test

STDcheck Review

Hair and Hair Loss

Best Hair Loss Treatment for Men

Best Laser Cap for Hair Loss

Kiierr Laser Cap Review

Relationships & Sexual Health

Best STD Dating Websites

Best Herpes Dating Websites

Best Erectile Dysfunction Treatment

Best Delay Spray

Best Prostate Massager

BlueChew Free Trial

Nutrition Guide

Found Weight Loss Review

BlueChew Promo Code

Best CBD for Arthritis

Best Incontinence Underwear for Women

Best Incontinence Underwear for Men

Fitness and Weight

Best Amino Acid Supplements

Best Muscle Building Stack

Vital Reds Review

Total Restore Review

Best NMN Supplement

Best NAC Supplement

Best NAD Supplement

Best Berberine Supplement

Mood and Energy

Best Nootropics

Best Saffron Supplement

Sexual Health

Best Testosterone Booster

Best Male Enhancement Pills

Best Volume Pills

Skeletal System

Muscular System

Cardiovascular System

Digestive System

Nervous System

Respiratory System

Urinary System

Integumentary System

Smart drugs designed to improve your memory are everywhere in 2024. We researched the top contenders and tried them ourselves to help you pick the right one for your needs.

Lee is a senior editor and writer at Innerbody Research. They received a bachelor's degree in Psychology with a focus in Neuroscience from Ohio Wesleyan University, and an MFA in Creative Writing from Northern Arizona University.

In this Review

We researched, investigated, tried, and compared the most compelling nootropic options of 2024 to help you find the right smart pill for your needs. If you’re short on time, here is the rundown of our top picks.

Summary of recommendations

• Best overall: Thesis
• Best budget pick: Focus Factor Original
• Best generalized nootropic: Mind Lab Pro
• Best for brain health: Thesis Logic
• Best for memory: Mind Lab Pro
• Best for stress and anxiety: Thesis Creativity
• Best for studying: Thesis Clarity
• Best non-stimulant: Mind Lab Pro
• Easiest to take: TruBrain Personalized Drinks
• Best range of products: BrainMD Brain & Body Power Max

Thesis is our top nootropic recommendation. Their formulas are scientifically backed and stimulant-free.

Thesis supplements help rebalance the brain, without negative habit forming side effects. Choose between 5 personalized brands to enhance your mental performance.

Shop on Thesis and take 10% off your first order with code INNERBODY.

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. As nootropics have emerged and proliferated in the supplement landscape, we’ve invested serious time to determine which are worth your consideration.

We’ve spent hundreds of hours researching and testing various nootropics, including specialized formulas, generalized nootropics, and individual ingredients. Over the course of our nootropic studies, we’ve read over 350 clinical studies examining the safety and efficacy of various nootropic ingredients. To get a first-hand look and feel, we ordered and tested nootropic supplements ourselves, meaning we’re speaking from experience — not just regurgitating what others have said.

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy. To keep things up to date, we monitor the nootropics landscape and update this page as information changes.

How we evaluated nootropics

Nootropics are complicated supplements, but that doesn’t mean it’s impossible for the average person to understand them. When we review nootropic supplements, we consider four main criteria:

• How well they work
• How safe they are and what precautions the manufacturers take
• How much they cost
• How convenient they are to purchase and use

Typically, a nootropic’s effectiveness is the most important criterion: no matter how good of a deal it is or how safe it may be, it doesn’t make sense to invest in a product that just doesn’t work. Safety ranks second above cost; your brain is a delicate organ, and many nootropics contain ingredients without a long history of adequate research, which calls their safety into question far more than something like a multivitamin. Those ingredients and a company’s testing routine vary much more dramatically than cost or convenience.

Thesis comes close to a clean sweep in our ratings in 2024, winning in effectiveness and convenience (with TruBrain as a close runner-up) and matching Mind Lab Pro in safety. It’s one of the most effective nootropics out there, with:

• Rigorous safety standards
• Research-backed ingredient lists that are well-dosed (which is astonishingly rare in the nootropic landscape)
• Lots of little conveniences that add up, like packets with each day’s serving so you don’t have to count pills
• Free one-on-one consultations to help you maximize the benefits you can get

The only area where Thesis falls short is its price: spending $79 or more per month on a nootropic is out of reach for many of us. If you have a tighter budget, Focus Factor has the most reasonable price point on our list by a long shot; it costs four times less per dose than our second least expensive nootropic, Hunter Focus.

Effectiveness

Winner: Thesis

An effective nootropic is one that makes a big difference in your mental state without overloading your system with thousands of unnecessary milligrams of botanicals, vitamins, minerals, and other ingredients. If 100mg works similarly to 10,000mg, it’s going to be much more effective to get 100mg in a blend. And when it comes to nootropics, effectiveness becomes slightly more complicated because there are two major categories:

• Generalized nootropics , which claim to increase memory and focus, reverse brain aging, and regulate mood all in one dose
• Specialized nootropics , which sink all of their focus into one area

Because of their jack-of-all-trade tendencies, generalized nootropics tend to be less effective than specialized nootropics.

We think Thesis is the most effective nootropic because of its reasonable dosing and, more importantly, its unique blend configuration. Where most other nootropics provide one formula, Thesis lets you try four of its six formulas in a Trial Kit before committing to your favorite (or favorites). Each blend is dedicated to a specific part of your cognition you might want to enhance, such as motivation and creativity, so you can utilize effective ingredients to treat the aspect of your cognitive health that’s most important to you.

Here's a short video showing the sort of package you'll receive in the mail if you order from Thesis, as well as sharing summary details about its effectiveness from our team who tested it:

TruBrain’s drinkable nootropics take a similar approach but are ultimately less effective because not every formula has the same scientific robustness as all of Thesis’, and the drinkable liquid means there are more ingredients necessary for a good flavor — like agave syrup, xylitol, citric acid, and cane sugar — that you just won’t see in a capsule nootropic like Thesis.

Runner-up: Mind Lab Pro

Despite having been around since the mid-1950s in some form, nootropics still often use lots of ingredients without much research that backs up positive effects on cognition. Because your brain is a sensitive and delicate organ that controls every part of your life, it’s critical that nootropic supplements are safe. The more research into a product or ingredient has behind it, the more we know about its safety and can make better-informed decisions. We consider the following factors to be critical for our safety scores:

• Clarity around ingredient lists (not hiding dosing information in proprietary blends)
• Transparent testing and manufacturing conditions
• Clear instructions on necessary tasks like cycling

Both Thesis and Mind Lab Pro are exceptionally safe nootropic supplements. Neither contains hazardous ingredients you’d need to cycle (though Thesis still recommends taking at least one day off a week from their nootropics, just in case), and both use ingredients that are backed by the latest research.

Both Mind Lab Pro and Thesis make their nootropics in GMP-certified , FDA-registered facilities, but Thesis is more transparent about its use of third-party testing for ingredient and formula purity. And more importantly, Thesis uses short lists of ingredients in doses that are closely aligned with scientific studies. Mind Lab Pro is mostly underdosed (only three ingredients are present at the same doses found in clinical studies), though their in-house study found the nootropic had great success matching, if not exceeding, said studies.

Winner: Focus Factor

New technologies — and supplements — are often much more expensive than ones that are simpler or have been around for longer. For the most part, nootropics follow this trend. Prices can range considerably depending on the manufacturer, ingredient list, and other factors but generally fit into one of two categories:

• $35 or below and lower quality
• $65 or above and higher quality

Among the group of nootropics that provide a reasonable formula, Focus Factor is our least expensive nootropic by a long shot. The company makes several different nootropic supplements, and its Original formula is one of the best and the least expensive per serving on our list. One 15-serving bottle costs $14.99, and costs per dose decrease as you buy bigger bottles. Even the next least expensive nootropic, Onnit’s Alpha BRAIN, costs more than twice as much per serving.

While some of the biggest nootropic companies make one product and others make dozens, here’s a breakdown of the costs and money-saving opportunities for our top picks’ most popular product in as close to a 30-day supply as possible. (All costs noted are pre-savings.)

Focus Factor doesn’t accept returns, which is a pain, but you can get both bulk deals and savings from subscription programs on your orders, which drops the price further. And it has the least expensive shipping across all of our favorite nootropic options, so while you can’t get it in stores yet, you can get it regularly shipped to your front door for very little.

Convenience

Runner-up: TruBrain

Nootropics aren’t the most convenient supplements. Most of the time, they require taking several medium-to-large pills with food in the morning. Depending on their ingredients, some will ask you to cycle your use. Cycling means that you take a few days, weeks, or months off to keep yourself from developing a tolerance or building up too much of a substance that could harm you in high enough doses. And while nootropics hopefully improve your memory enough to remember when you need a refill, subscription services that are easy to modify or cancel improve a nootropic’s convenience score.

Every formula from Thesis contains multiple capsules, which is a little inconvenient but standard for nootropics. However, its serving sizes are small for nootropics, and the company lets you opt in or out of a caffeinated formula whether or not you’ve purchased either form. Its caffeine pills come as a separate white capsule, so you can identify and skip it if you’d rather not give up your morning coffee. Every day’s serving is packaged in an individual plastic bag, and while you’ll have to pull out a pair of scissors to open it (there’s no tear notch), you won’t have to count capsules and can easily slip the packet in your bag or pocket for on-the-go use.

Except for TruBrain, all other nootropics come in homogenous capsules or tablets in a big bottle, which means lots of counting and a commitment to either caffeinated or non-caffeinated formulas. Add in the excellent starter kit so you can try four of the six formulas before committing to your favorite few, and it becomes clear why we consider Thesis to be the most convenient nootropic.

On the other hand, you can take TruBrain’s six nootropic formulas in three different forms: liquid pouches (like squeezable applesauce), capsules, or powder sticks. It also offers a “brain aging” supplement with its own separate formula. This is the only liquid nootropic worth its salt right now, providing a convenient option for people who can’t swallow pills. Like Thesis’ packets, it’s also easier to carry and take with you, and you won’t have to worry about dividing up your daily dose.

How our top picks compare

Some of our favorite nootropic companies center on one formula. Others have broad horizons and create multiple lines of products. It can make trying to compare nootropic supplements confusing at best. To simplify things, we’ve created two charts:

• One comparing the companies themselves
• One comparing our favorite products from each brand

Here’s a closer look at our top products from each company. This isn’t an exhaustive list, and we’ll go into more detail on a few other products from these same companies later, but this will give you a good starting point in your investigation.

Here are a few important facts about the companies themselves:

What are nootropics, and how do they work?

Broadly speaking, nootropics are substances that improve your cognitive functioning. This definition is generous as it applies equally to supplements, prescription medication, and recreational drugs. In recent years, the supplement industry has grabbed onto this term to describe products with vitamins, minerals, amino acids, and botanicals that are designed to improve your brain game. We’ll follow suit and focus on nootropic supplements in this guide.

The first nootropic to use the term was a drug developed throughout the 1950s and 60s called piracetam. It was intended to treat anxiety and provide patients with a soothing experience that might even lull them to sleep. 2 The effect was quite different than what its creators intended, as users reported sharper focus, and later testing pointed toward improved memory. (At the time of writing, the FDA still hasn’t approved piracetam for use in supplements or as a prescription medication, though many still take it.) 3 Nootropics also include prescription medications like Adderall and Ritalin, as well as medications for dementia and Alzheimer’s disease. Caffeine is also a nootropic substance and an ingredient you’ll find in many nootropic supplements.

Nootropic supplements may have one ingredient, or they may have dozens. Some ingredient lists look similar to multivitamins, and others focus more on cutting-edge botanicals. Because no two brains are identical, the best nootropic for our team or other people may not work for you, but we’ll provide all of the research and information you need to make the best decision in this guide.

Contemporary nootropics generally have three main goals:

• Protect your brain from damage
• Improve your memory, learning, and attention
• Regulate your mood

Not every nootropic does all three; some have a more specific focus, such as improving your learning ability or neuroprotection. These kinds of nootropics are called specialized nootropics. Others, called generalized nootropics, try to improve your brain’s function holistically across all three categories. But either way, all nootropics are designed to help your brain work more efficiently.

As cognitive enhancers, nootropic ingredients alter how your nerve cells and neurons work. This takes place in a variety of ways, including:

• Affecting circulation to the brain
• Positively impacting signaling pathways
• Combating oxidative stress
• Regenerating and strengthening neural connections
• Improving mitochondrial function
• Increasing the expression of neurotransmitters, like acetylcholine and dopamine

Common nootropic ingredients and studies of them

To better understand the potential mechanisms of action in any nootropic, we have to take a closer look at its ingredients. Unfortunately, there are several hundred ingredients used in these kinds of supplements, yet manufacturers claim that all of them work equally well. This, obviously, isn’t true. A vast majority of nootropic ingredients have mixed evidence of their benefits and few research studies verifying these benefits.

That said, there are some nootropic ingredients that research supports wholeheartedly (or close to it). Here are nine of the best ingredients you should consider noteworthy when picking a nootropic supplement.

Choline is an essential nutrient that allows our bodies to make phosphatidylcholine, a fatty acid necessary to build our cell membranes. There are several choline-related ingredients you might find in a nootropic supplement, including choline, phosphatidylcholine, citicoline, and alpha-glycerophosphocholine (alpha-GPC). The latter two are the most common in nootropic supplements; between the two, citicoline works more effectively, but alpha-GPC is more common (though the research suggests that alpha-GPC may not produce statistically significant results over caffeine or a placebo). 4 Citicoline more reliably improves episodic memory without serious side effects and is a contender for a future possible dementia or stroke treatment, though more research is necessary. 5 6

Ashwagandha comes from a plant commonly used in Ayurvedic medicine to lower stress and anxiety levels, improve sleep, and regulate your HPA axis (which, for men, can also boost testosterone levels). 7 In contemporary research, these practices hold up well, consistently lowering self-reported anxiety levels and improving sleep quality by up to 72%. 8 9 By improving your sleep and lowering stress, ashwagandha seems to work as a natural nootropic, but there’s some evidence it may also improve executive functioning in people with neurological and severe psychiatric disorders. 10 Our testers noted significant drop-offs in their stress and anxiety levels when they tried ashwagandha supplements .

Tyrosine is an amino acid commonly found in nootropic supplements because our bodies use it to create dopamine and norepinephrine. Having higher tyrosine levels means you’ll have more materials to make dopamine and norepinephrine, so your body is less likely to fall flat when you need them most. Studies show that higher tyrosine intake translates to better resilience in stressful or cognitively demanding situations, better short-term memory, and improved cognitive flexibility. 11 12 You’re most likely to see tyrosine as NALT (N-acetyl L-tyrosine) in supplements.

You might find you don’t function the same without your morning cup of coffee . That’s thanks to caffeine, a potent nootropic. While scientists don’t know exactly how caffeine works in the brain, the running theory is that it prevents adenosine (which gradually makes you sleepy over the course of a day) from building up in your brain. This makes you feel more alert than you would be without caffeine. Repeatedly in scientific studies, caffeine improves human attention spans as much as prescription stimulants. 13 A 2022 review also outlined how caffeine has neuroprotective effects against Alzheimer’s disease in animal models, though this still needs to be tested more rigorously in humans. 14 And it doesn’t take much caffeine to see these improvements — even 100mg of caffeine, or what you’d get from one cup of coffee, is enough to benefit your brain.

Most common in tea leaves, theanine is another amino acid that’s key for our relaxation. Like ashwagandha, it’s long been known to reduce stress, particularly when used in conjunction with caffeine (where theanine reduces the jittery effect so common when you have a little more than you need). 15 There’s a link between L-theanine and improved sleep quality, too, though there still needs to be more research on this subject before anything can be stated definitively. 16

Rhodiola rosea is an herb common in northern Europe that’s similar to ashwagandha. It’s surprisingly effective at reducing fatigue, calming your nerves, and lowering stress levels. 17 Rhodiola also works in combination with tyrosine to improve your focus during stressful times. 18 There’s some research on its role in learning and memory that’s generally favorable, but most of these studies focus on animals, not humans. 19

Bacopa monnieri is a botanical nootropic ingredient that’s common for a good reason: it’s one of the better-studied nootropic ingredients and improves choline levels, giving ingredients like citicoline or alpha-GPC a boost. According to a 2014 meta-analysis, it seems to improve your attention and decrease reaction time. 20 However, studies are mixed on whether or not bacopa extract improves memory recall, too. 21

There are a few kinds of ginseng you might find, but they can generally be separated into Asian ginseng (including Korean red ginseng, a particularly potent form) and American ginseng. Generally, Asian ginseng improves cognitive performance more than American ginseng, though the American form does still have cognitive enhancement properties. 22 It generally improves concentration, scanning ability, and memory recall and is thought to stabilize the nervous system and decrease neuroinflammation. 23 Ginseng seems to be particularly potent when paired with ginkgo biloba, another nootropic botanical. 24

Huperzia serrata produces a potent compound known as huperzine A. Huperzine A raises your acetylcholine levels by limiting the amount of acetylcholinesterase (which breaks down acetylcholine) released. This essentially means you’ll have more acetylcholine available for synapses to take up for longer. It has potent antiepileptic and neuroprotective effects and, when used correctly, is perfectly safe. 25 However, because nootropic supplements aren’t regulated by the FDA, there’s a greater likelihood that supplements containing Huperzia serrata can be dangerous. When too much acetylcholine accumulates (known as cholinergic toxicity), you can experience things like headaches, nausea and vomiting, and confusion, and it can lead to overdose in extreme situations.

It’s important to note that just because an ingredient works well in one research study, it doesn’t mean the ingredient will work exactly like that in your body. Our brains are just as individual as our fingerprints, shaped by both genetics and our lived experiences. Everything from our weight and what we ate for breakfast to our parents’ reactions to medications can make individual nootropic ingredients interact differently from person to person. Likewise, these ingredients’ doses and interactions with other ingredients can change a lot about how they work. Some ingredients might keep others from working, while others might boost others’ ability to work. Most of this information hasn’t been properly researched yet, so it’s hard to predict how a nootropic will work without an independent study of the product. (We take a look at the four studies that have been done on specific nootropic supplement formulas later in this guide.)

Keep an open mind while you’re starting to try nootropics. We recommend starting with nootropics supplements that have relatively short ingredient lists so you can quickly pinpoint ingredients that do or don’t work for you.

There are some other classes of ingredients that may not directly affect your brain like you might expect a classic nootropic to, but that are still important to support your brain’s overall health.

Like the rest of your body, your brain and central nervous system need amino acids to make proteins. It’s well-known that the brain uses three amino acids — tryptophan, tyrosine, and phenylalanine — to make the three major neurotransmitters (serotonin, dopamine, and norepinephrine, respectively). 26 But a 2020 study found seven amino acids that improved older adults’ cognitive, social, and psychological functioning: leucine, lysine, isoleucine, histidine, valine, phenylalanine, and tryptophan. 27 The only amino acid that we know doesn’t make much of a difference in your brain is glutamine. You might see some of these amino acids as acronyms like NALT (tyrosine), too.

Fatigue and brain fog are extremely common symptoms of vitamin and mineral deficiencies. B vitamins (especially B6, B9, and B12), vitamin D, iron, and magnesium are the most important vitamins and minerals for your cognitive health. Though direct analyses often yield mixed results, fatigue and brain fog make a big difference in how easily thoughts come to you and how good you feel, and vitamins and mineral deficiencies are more common than you might expect. 28 Healing these deficiencies is often just as good as — if not better than — just taking a nootropic supplement.

Oxidative stress is caused by a buildup of free radicals — reactive oxygen species missing electrons that cause damage to nearby cells. It occurs due to aging, environmental pollution, exposure to tobacco smoke, food breakdown in our digestive system, and dozens of other small factors that add up over time. With enough buildup over time, oxidative stress can cause permanent damage and may lead to things like heart disease and cancer. This damage is most common and harmful in the brain due to its massive oxygen consumption and the fact that adult brains don’t replace dead and dying cells.

Antioxidants have free electrons that they donate to the raving oxygen molecules, taming them and allowing the body to repair damage. There are thousands of antioxidant compounds, but things like omega-3 fatty acids, vitamins C and E, polyphenols, and carotenoids are potent antioxidants. Antioxidants are most useful when consumed alongside chemicals present in their natural forms like fruits, vegetables, and fish , but they can still help on their own in a supplement .

Insider Tip: You likely won’t see pure amino acids in a nootropic supplement. Instead, you’ll see something with a letter before it, like L-theanine. This letter represents the direction the molecule is turned in production — L- means it’s all turned to the left, D- means it’s all turned to the right, and DL- means there’s some of both. L- amino acids are absorbed best by the body and are almost always cheaper.

Tolerance and habituation

Some ingredients require a little more care to use properly. Tolerance (our brains physically adapting to a new situation) and habituation (our psychological adaptations) can both be present while you’re using nootropics. (These are both different from addictions, which involve an inability to control your use even when you want to and developing a dependence on it for daily functioning, among other features. It is possible to become addicted to some nootropics, though it’s not common.)

If a nootropic asks you to cycle, or occasionally take a few days off from taking it, it’s likely that it contains ingredients that could build a tolerance. These generally are ingredients that affect your brain’s acetylcholine levels, like huperzine A.

Ingredients to avoid

Some ingredients with little to no evidence still find their way into nootropic supplements. There aren’t many that are inherently dangerous; vinpocetine can induce miscarriages or birth defects if taken while pregnant, and huperzine A can cause acetylcholine toxicity if taken in extreme doses for too long. But plenty of ingredients are essentially filler. Sadly, most nootropics will contain at least one ingredient with questionable research behind it. Here are some of the worst offenders we’ve found, even in our favorite nootropics:

• Artichoke extract . There’s only one study (from 2022) on this topic. It suggests artichoke extract may reduce some biomarkers associated with Alzheimer’s disease, but there’s no evidence it can otherwise support your brain. 29
• Oat straw extract . There’s no clinical evidence this does anything for your brain.
• Dimethylaminoethanol (DMAE) . This antioxidant was sold as an alternative to ADHD medication called Deanol between 1950 and 1980, but it was recalled due to a lack of scientific evidence on its safety. 30 There hasn’t been much, if any, research on it since.
• Coleus forskohlii extract . This mint-like plant is advertised as being able to do a lot for an aging brain, but there’s no evidence it has any cognitive benefits.
• Glutamine . Despite being the most common amino acid and protein building block in your body, it mostly works on rebuilding muscles post-workout unless you’ve experienced a lack of oxygen to the brain (and even that finding is tentative). 31
• Taurine . Despite how frequently you might see it in energy drinks, and though taurine deficiencies are common in people with cognitive dysfunction, there’s no clear evidence taking taurine improves cognition. 32

Studies on our favorite nootropics

Because nootropic ingredients vary so wildly in their clinical support and almost no research studies look at ingredients in combination with each other, it’s always nice to see a company run a study on its product. There are some clear biases possible — when a company funds a study, the researchers may feel pressured to produce certain results — but some information is better than none.

Four of our top picks tested their nootropics in some capacity: Focus Factor Original, Alpha BRAIN, Mind Lab Pro, and Qualia Mind. In general, Mind Lab Pro worked the best on reaction time, anticipation, memory recall, and information processing (particularly among the 30-and-over crowd), and Focus Factor Original also had some significant positive findings on recall ability. 33 34 Alpha BRAIN has two studies under its belt, both of which are somewhat mixed but suggest that it may improve verbal memory, and Qualia Mind’s findings were disappointing — while participants reported significant improvements across six cognitive categories, they weren’t significant over a placebo. 35 36 37 These findings ultimately make a big impact on how we judge these supplements, and while nothing’s going to work perfectly for every person, it provides insight as to the strengths and weaknesses of these products.

You can read more about these studies in the products’ full reviews, linked under each product breakdown in this guide.

Are nootropic pills safe?

No nootropic pills are created equally, so it’s hard to say they’re all safe. Many are safe for healthy adults who don’t take any prescription medication, but that leaves out two-thirds of all U.S. adults, according to Georgetown University’s Health Policy Institute. 38 And nootropics can also interact with other supplements, so you’ll want to cross-check ingredient lists. As with any supplement, we encourage you to talk to your doctor before starting a nootropic to ensure it doesn’t interfere with any conditions you have or medications you take.

Our top recommendations generally use ingredients in safe doses for most people. They err on the side of caution and are more likely to under-dose than overload your system with the latest and greatest botanicals, which is frustrating in practice but better for you in the long term. This isn’t the case for every supplement — we’ll point out which ones to approach with extra caution in our product breakdowns — but, in general, you’re more likely to experience fewer effects than a laundry list of side effects.

Side effects and contraindications are always a possibility, though. Some ingredients cause more side effects than others. (Since many nootropics have at least 90mg of caffeine, we recommend curtailing your coffee and tea consumption until you know how this new energy source affects you.) Keep an eye out for things like headaches, stomach aches, and dizziness when you’re starting a nootropic. If you find these symptoms don’t go away after a day or two of use, stop using them and contact your doctor. It may be a poor ingredient fit, or nootropics might just not be a good idea for you.

Some nootropics will require you to cycle (take days off in your weekly dosing routine). It’s inconvenient and a bit of a pain to have to remember, but it’s important for your health to follow these instructions. Taking a few days off keeps them from building up in your brain, either flooding your body with excess acetylcholine that can’t get cleaned up (and can cause problems like muscle twitching or decreased respiration) or causing you to develop a tolerance or dependency. Cycling requirements generally depend on a few ingredients — notably huperzine A and other acetylcholinesterase blockers — included in a given formula.

Other ingredients you might see that mean you should regularly take time off include:

• N-acetyl cysteine (NAC)

Caffeine, for example, is an addictive stimulant (as you may know if you drink a cup of coffee each morning and don’t feel right without it), whereas NAC regulates the amount of glutamate released by your body. Cycling NAC prevents building a tolerance, which can have effects on your mood — like an inability to feel pleasure — whereas cycling caffeine can keep you from developing a dependency on it.

You might find that taking your nootropic five days a week and resting for two days works for you. Taking it for three months straight, then stopping for one month, may be better for others. Many nootropics that suggest you cycle have recommendations on how to plan your weeks, but ultimately, deciding the right routine is up to you and how you feel while taking the nootropic.

Who should (and shouldn’t) try a nootropic?

Most of us can understand a desire to be smarter. Many of us have struggled through brain fog and confusion after several nights of staying up too late. A nootropic sounds like something we could all use, but some populations would benefit more from adding it to their routine, and others should stay away at all costs.

Pregnant people, nursing parents, and children under 18 should all avoid taking standard nootropic supplements. There are a few nootropic supplements specifically designed for children (including types from Focus Factor and BrainMD), but we don’t know enough about how they might interact with a developing fetus to state they’re safe for pregnant people.

We always strongly recommend sitting down with your doctor before starting any new supplements, especially nootropics. Your situation may be unique, and they’ll have the best sense of what might work for you. They may also order lab tests to ensure you don’t have any deficiencies, disorders, or other health problems that could be causing your cognitive symptoms.

Psychiatric and neurological medications can cause some of the biggest problems when combined with nootropics. (We’ll explore this in more depth shortly.) You should also avoid nootropic supplements if you’re taking:

• Blood thinners like warfarin
• Levodopa (L-Dopa)
• Cholinesterase inhibitors like Aricept or Reminyl
• Insulin or diabetes medication
• Immunosuppressant medications

Likewise, several conditions can be exacerbated by nootropic supplements. Not every nootropic will affect all of these conditions, but if you have anything listed below, be particularly cautious about starting a nootropic.

• Kidney disease
• Liver disease
• Thyroid disorders
• Heart problems (especially if you have bradycardia, a slow heart rate)
• Lung conditions like asthma and COPD
• GI blockages or stomach ulcers
• Urinary tract blockages
• High blood pressure
• Endocrine disorders (such as diabetes, thyroid problems, or low testosterone)
• Phenylketonuria (PKU)
• Muscular dystrophy

Nootropics also don’t interact well with drugs or alcohol. Some nootropics may be safe to have alcohol in moderation (such as a glass of wine with dinner) while taking it, but it’s generally best not to combine the two for your liver’s sake. Ingredients like green tea extract can cause liver inflammation, which is exacerbated by alcohol. 39 Recreational drugs generally increase either dopamine, serotonin, or glutamate (inhibiting GABA), so adding nootropic ingredients that do the same thing can lead to side effects like tremors or worse.

Studies on individual products — such as the self-funded study on Mind Lab Pro — regularly find that nootropics work best for the over-30 crowd. This doesn’t mean that they can’t help college students or young professionals, but because your 20s are generally some of your healthiest years, there’s less age-related dysfunction for the nootropics to address. One of our 25-year-old testers who tried Thesis, for example, found that it supported their focus and clear thinking as much as — if not more than — a 37-year-old peer tester. Like all other factors, age can make a difference, but your youth alone won’t keep you from getting something out of a nootropic supplement.

Psychiatric and neurological conditions

If you have a psychiatric condition — even mild depression or generalized anxiety disorder — you are more likely to experience negative side effects or worsening symptoms by taking a nootropic. This is especially true if you take neurological or psychiatric medications, which act on the same neurotransmitters as nootropics. Having too much of any neurotransmitters is just as bad as not having enough and can lead to unpleasant side effects like headaches, stomach aches, tremors, or serious complications like serotonin syndrome. 40

This neurotransmitter is responsible for our mood, sleep, and digestion, and it stabilizes other neurotransmitters. It’s implicated in many psychiatric disorders, most notably depression, and is the subject of many psychiatric mediations. This includes SSRIs (such as Zoloft, Prozac, Celexa, and Paxil), SNRIs (such as Effexor and Savella), MAOIs, tricyclic antidepressants, and some mood stabilizers like lithium. Nootropic ingredients that affect it include acetyl-L-carnitine, Bacopa monnieri extract, L-tryptophan, and Zembrin (Sceletium tortuosum).

Dopamine plays two roles in our brains: motor movement and reward. It’s responsible for pleasure and plays a critical role in our executive functioning. 41 There’s a huge range of medications that influence dopamine: stimulants like Adderall, Ritalin, and Concerta; medication for Parkinson’s disease like Mirapex; antipsychotic medication (which primarily targets dopamine but may also affect serotonin) like Seroquel, Risperdal, and Abilify; and prescription nootropics like L-dopa and modafinil. Many ingredients in nootropic supplements also affect your dopamine system, including Bacopa monnieri extract, citicoline, L-theanine, L-tyrosine, pyrroloquinoline quinone (PQQ), and uridine.

Like dopamine, acetylcholine controls our muscles and learning, memory, and attention. Cholinesterase inhibitors prescribed for dementia or mild Alzheimer’s disease keep acetylcholine in a neuronal synapse, as do medications treating myasthenia gravis and many eye conditions. 42 Acetylcholine-influencing compounds are extremely common in nootropic supplements. The most common ingredients you’ll find are alpha-GPC, citicoline, and huperzine A, but you might also find DMAE, donepezil, and galantamine.

Glutamate is the primary excitatory neurotransmitter, which makes it easier for neurons to send impulses where they need to go. This speed also means it’s critical for learning and memory. While there aren’t currently many prescription medications that directly affect glutamate, there are several companies investigating its potential for treating severe treatment-resistant depression, substance abuse, and obsessive-compulsive disorder. Ketamine, a dissociative anesthetic, works along the glutamate pathway and has shown promise as a potential treatment for severe depression in small doses. In nootropic supplements, caffeine, cocoa, theobromine, and l-theanine may influence glutamate.

GABA is the primary inhibitory neurotransmitter, turning down the rate of electrical impulses in the brain. Antiepileptic medications, like Lamictal and valproic acid, raise GABA levels. So can traditional anti-anxiety medications like benzodiazepines (Xanax and Klonopin) and barbiturates (Seconal), Gabapentin, and some sedative-hypnotic sleep medications like Ambien. L-theanine can influence GABA, as can phenibut and kratom, but you’re more likely to see GABA on its own as an ingredient in nootropics or on its own as a supplement.

Best overall, best for brain health, best for stress and anxiety, and best for studying

• Available with or without stimulants
• Useful starter pack lets you try up to four formulas at once
• Wellness coaching included
• Outstanding customer support
• Free shipping every time
• Use code INNERBODY for 10% off your first order
• Money-back guarantee is only 30 days

Between strong testing measures and even more robust customer service — along with convenient packets delineating daily doses that are easy to travel with —- Thesis easily ranks as one of our favorite nootropic companies and is our top pick among nootropic supplements in 2024. The company relies on strong science to back its empathetic messaging, emphasizing that having cognitive deficits isn’t a cause for shame but that there are ways to improve your brain in a healthy way.

The company offers six different formulas, posed as working well in pairs. These include:

• Clarity and Logic
• Energy and Motivation
• Creativity and Confidence

Generally, each product contains fewer than 10 ingredients, including caffeine and L-theanine. (You can read more about the individual ingredient breakdowns in our full review of Thesis .) However, there are clear goals for each formula:

• Clarity : increasing blood flow to the brain and stimulating acetylcholine, cutting brain fog
• Logic : improving communication throughout the central nervous system and cell membrane quality
• Energy : boosting cellular energy and blocking adenosine
• Motivation : increasing blood flow to the brain and boosting cellular energy
• Creativity : anti-anxiety and antidepressant
• Confidence : anti-anxiety and boosting dopamine levels

Our testers found that Clarity gave them the biggest effects, with a significant boost to their focus great for a several-hour study session, but some experienced a sense of dissociation or a headache as it wore off. One tester ultimately preferred Logic for a subtler, longer-term sense of clarity and better memory recall.

If you aren’t sure where to start, you can take a short quiz on Thesis’ website to determine which one would be best for you. Most quiz results offer more than one formula in the form of a starter kit. This kit allows you to try each blend for a week to see how they affect you, eventually choosing one (or more) to become your daily nootropic. You can also continue to receive the starter kit on a subscription basis and use different nootropics for different situations.

Insider Tip: If you already know what you want to try, you can skip the quiz by navigating to the Starter Kit page. The first question in the FAQ, halfway down the page, has a link to “Get Started,” where you can assemble your kit yourself.

Special Offer from Thesis: 10% OFF your first order with code INNERBODY

Quite possibly the best part of using Thesis’ is that you can easily toggle caffeine on or off with any formula. Other companies either don’t offer a stimulant-free option or have a different formula that may not be as effective. Thesis simply lets you order any of their formulas without stimulant ingredients included. Our testers did find that caffeine enhanced the effects, so if you aren’t sensitive to caffeine or are looking for the biggest boost, we still recommend going with the caffeinated form. Plus, if you decide later that you don’t want to take caffeine, Thesis keeps each caffeine pill as a separate capsule (the smallest white capsule in each packet), so you can easily ditch it.

Thesis also provides wellness coaching to all subscribers, so you can get the most out of your nootropics and find new ways to improve your life and your brain.

Several companies in this guide take pains to test their products, looking at purity and dosage in particular. But Thesis is among the few who rely on third-party testing rather than internal testing. One of the reasons the ingredient lists in Thesis nootropics are shorter than some of the competition is that Thesis only uses ingredients that are either Generally Recognized As Safe by the FDA or have undergone phase III clinical trials. The only ingredient that’s of any potential concern is ashwagandha, which isn’t safe for people who have thyroid problems.

Pricing and payments

Thesis has a particularly unique structure. If it’s your first time ordering from them, you’ll have to take a quiz to identify what formulas might fit your needs best. Since nootropics can be such a dense, confusing industry to navigate, it’s a definite plus that Thesis helps you select what might work best for you based on real cognitive testing measures and lets you try more than one formula at once (since a test can only reveal so much). Those are two big benefits you won’t find with any other nootropic.

Whether you stick with the starter kit or customize your order, the prices for a 28-day supply remain the same:

• One-time purchase: $119
• Monthly subscription: $79

Subscription orders ship every 30 days, and you can’t change their frequency, but you can pause or cancel at any time.

Insider Tip: We recommend you consider starting a subscription for the $30 discount; you can cancel, pause, or skip shipments at any point without hassle, though there are a few more steps involved than other subscription canceling menus. Luckily, you won’t have to pay for shipping at any step unless you need a refund.

If you aren’t happy with your Thesis nootropics, you can reach out to the company’s customer service team. They’ll recommend adjustments to a schedule or suggest other products to try first. When you know you want a refund, you’ll need to go to the returns page, which sends you an email link to actually process a return. You can send back any unopened box of Thesis for a full refund within seven days of delivery if you have more than you need, or you can refund one month’s supply within 30 days of purchase. You’ll have to physically mail back whatever you have — even if the box is empty — and Thesis doesn’t cover the cost of return shipping.

Mind Lab Pro

Best for memory and best non-stimulant

• Supported by independent research
• Stimulant-free
• Vegan formula
• Flexible dosing options
• Uniquely socially conscious among nootropics
• Free bottle with a purchase of three
• Limited ingredient dosages
• Free shipping on the largest orders only
• Complicated return policy
• No subscription options

Mind Lab Pro has a lot going for it, including third-party testing and research. Its study is the most successful self-funded study out of any nootropic on our list, displaying the best results after three months of taking Mind Lab Pro in the following areas:

• Simple choice and reaction time
• Anticipation (predicting the next step in a structure)
• Information processing (especially for people 30+)
• Immediate and direct recall (memory)

The supplement doesn’t use any novel ingredients, and its components all boast research of their own that show safety and efficacy. These include citicoline, lion’s mane mushrooms, and Rhodiola rosea, among others. Notably, though, all but three (two B vitamins and lion’s mane) are all underdosed compared to the supportive outside research. Luckily, Mind Lab Pro’s study is so successful that it’s still very likely you’ll see positive results from this nootropic.

They also have one of the lowest allergen profiles of any nootropic, as their formula is:

• Gluten-free
• Synthetic additive-free
• Caffeine-free
• Non-irradiated
• Vegan-friendly

We think this is your best option if you want a generalized nootropic and know you don’t want a caffeinated supplement. You can learn more about its ingredient profile and how it’s changed over time in our full review .

Because Mind Lab Pro only offers one product, the pricing structure is simple:

• One Bottle: $69
• Two Bottles: $138
• Three Bottles (plus one free): $207

Shipping on three-bottle orders is free, but smaller orders incur a charge of $9.95 for standard (3- to 10-day) or $14.95 for expedited (2- to 4-day) shipping. Mind Lab Pro has also kept in mind that mail times have slowed substantially in the last few years, extending their delivery windows by a few days.

Their refund policy is confusing, depending on whether you just want a refund or want to use their money-back guarantee.

You can get a refund in full within 14 days of delivery, assuming you haven’t opened the bottle. The money-back guarantee only applies to the first bottle in your first order, but you can claim a refund through this policy within 60 days, and you’ll have to pay shipping both ways. This reduces your expected refund amount to about $40.

Easiest to take

• Several delivery methods into the body
• Various bundles available
• Great for people who can’t swallow pills
• Shots are extremely convenient
• Specific supplement for brain aging
• Free shipping
• No money-back guarantee
• Contains full-spectrum CBD oil
• Drinks contain high-FODMAP ingredients

Designed by UCLA-trained neuroscientists, TruBrain offers a novel delivery method for their most popular nootropics. Each product is available in liquid form and stored in a small pouch. You can crack one open and drink it in short order, and it doesn’t matter if you have any trouble swallowing pills.

There are seven available flavors:

• Sleep: uses GABA, melatonin, and 5-HTP to relax you
• Mellow: an all-around balanced and low-dose nootropic with Noopept, vitamin C, NALT, centrophenoxine, magnesium, L-theanine, and CBD oil
• Matcha: a green-tea-based drink with magnesium, Noopept, and NALT designed to increase mental clarity
• Mushrooms: a botanical blend with four mushrooms and vitamin C intended to promote cognitive health
• Medium : identical to Mellow, but without the CBD oil
• Strong: a caffeinated version of Medium
• Extra Strong: Strong plus 150mg of Adrafinil, a non-prescription version of modafinil

Mellow, Medium, and Strong are all nearly identical; Mellow adds functional CBD oils , and Strong adds caffeine. While they’re easy to take, you’ll need to be careful if you can’t take CBD or regularly need drug testing since full-spectrum CBD oil does contain a small amount of THC. (Though not enough to provide any psychoactive effects, the full-spectrum CBD oil in TruBrain could potentially cause you to fail a drug test.) Overall, the doses are okay, and TruBrain picked somewhat unconventional ranges of ingredients; Noopept is a strong, branded nootropic with some more serious side effects than normal, but there’s little research supporting most of the mushrooms included in the Mushrooms flavor despite not having any major known side effects.

Customers generally report that the flavors are pleasant, though there are a significant number of other ingredients added to make these drinks palatable. Overall, we think that TruBrain’s unique form makes their drinks interesting and a good option for people who don’t like taking pills, but they don’t offer as much value on a supplemental level as something like Thesis, which has many similar customizable aspects, starter kits, and trials and more advantageous formulas.

If you aren’t crazy about the thought of drinking your nootropic, TruBrain has shifted its capsule offerings to encapsulate all seven formulas (pun intended) as TruBrain Capsules . Now, you can get one bottle of 30 servings in every formula for the same flat price, which varies depending on how you’re ordering it. This payment structure is almost identical to Qualia Mind’s, though you’ll get a much more succinct ingredient list and a few more servings for $10 more on your first order.

You can get these drinks with both bulk (from 10 to 60 pouches per order) and subscription deals (10% off every delivery). Uniquely, you can also prepay and save up to a year in advance for 30% savings if you know you like them and will continue to drink these supplements through the subscription program. You can choose exactly how many of which flavors you want, which is a nice bonus.

If you live in the U.S., you can also try 10 drinks for $29 with free shipping, though you won’t be able to pick and choose exactly how many of each flavor you’ll get. Note, though, that it automatically signs you up for a 20-drink monthly subscription; if you don’t cancel within two weeks, you’ll be charged $59/month for a box of 20 TruBrain drinks.

Clockwise is TruBrain’s brain aging supplement designed to counter the effects of time on cognition and memory. It contains nicotinamide, a B vitamin that can increase NAD production and mitochondrial functioning. That improved mitochondrial function should be able to address multiple systems, not just the brain.

Clockwise also contains green tea extract, vitamin C, and alpha-lipoic acid, among other ingredients in smaller quantities. However, note that these capsules are on the larger side, so they aren’t as accessible for people who have trouble swallowing. In that case, stick with TruBrain’s custom drinks.

One bottle of Clockwise costs $69, or you can subscribe and get bottles for $65 per month. (Those prices have gone up $4 and $6, respectively, in the last year.)

Powder Sticks

Unlike the shots, which are premixed, TruBrain’s powder sticks are designed for you to mix with water or a beverage of your choice. They contain Noopept, a generous dose of vitamin C, and several other nootropic ingredients. TruBrain uses xylitol, monk fruit, and stevia as sweeteners, so there’s no added sugar.

TruBrain Powder Sticks can make a good substitute for a mid-day cup of coffee. Each one contains 100mg of caffeine.

TruBrain Powder Sticks cost $59 for a one-month supply, or $55 per month if you subscribe.

TruBrain Bars

These bars are one of the few solid, edible delivery methods for nootropics. They contain Noopept, citicoline, and theanine, along with several sources of healthy fats like chia and flax seeds. Their macronutrient balance isn’t the best among protein or meal replacement bars, but these really belong to a different class than those.

TruBrain Bars currently come in just one flavor: triple cacao. They’re primarily sweetened with dates but also contain stevia.

You can get a box of 12 or 24 from TruBrain, and here’s how they price out:

• Box of 12: $55/box or $49/box with a subscription
• Box of 24: $99/box or $89/box with a subscription

Other TruBrain products

In addition to their signature shots, TruBrain offers a handful of other products, some of which are nootropics. (Others include ketogenic powder, coffee, and protein bars, all designed with brain health in mind.) TruBrain has a ‘prepay and save’ system on select products that allows you to save up to 30% when you buy in bulk. Here’s how it breaks down:

• 3-month supply: 10% off
• 6-month supply: 20% off
• 12-month supply: 30% off

You can get free shipping on any order that costs more than $55. TruBrain’s return policy is quite strict and will only accept a return if you send back an unopened box within seven days of delivery (not just the products themselves, but the container they’re delivered in). You also won’t be refunded the cost of shipping.

Focus Factor

Best budget pick

• Extremely inexpensive
• Almost all formulas are uncaffeinated
• Extensive ingredients list
• One of two companies to make a kids’ formula
• Gummies and drinks available
• Comes with its own companion app
• Some formulas are particularly unsafe for pregnant people
• Unclear nootropic dosage
• Some ingredients lack long-term safety data
• No safety and testing information available

Focus Factor has its hands in several different areas of your cognitive health, branded and packaged specifically to help you while also providing things like energy drinks and partnering with NASCAR. Their Original formula includes a litany of ingredients connected with higher brain function. Some of these include:

• L-Glutamine
• Bacopa monnieri​ extract
• Phosphatidylserine
• Vinpocetine
• Electrolyte concentrate
• Huperzine A
• More than a dozen vitamins

Focus Factor provides a dose for their proprietary blend of nootropics, but they don’t reveal the quantities of individual ingredients in their blend. They do have specific measurements for each of their vitamins and minerals because it’s required by law, but everything else hides under the blend label. And that blend is relatively small, too — Focus Factor Original contains only 640mg of the entire blend, whereas most successful studies use that much on one ingredient alone.

A self-funded study found moderate success, improving participants’ scores on a verbal learning test over six weeks with no complaints of serious side effects. However, because it has huperzine A (albeit in a likely very low dose), you may find you need to cycle this nootropic.

One important ingredient is vinpocetine, which is present in Focus Factor Original. Vinpocetine is a known teratogen, meaning it might cause birth defects and miscarriages if someone consumes it regularly or in a high enough dose while pregnant. Nootropics aren’t generally a good thing to take while pregnant or lactating, but you should especially stay away from Focus Factor for your baby’s health. There’s no clear information on Focus Factor’s website about the products’ safety, nor any information about in-house or third-party testing, and asking customer service doesn’t provide any new knowledge, either.

Ultimately, if you’re already taking a multivitamin, you likely won’t get anything new out of Focus Factor. However, if your general nutrition needs a boost or if you’re hesitant to try a potent nootropic, Focus Factor Original could be a good fit. We don’t recommend any of Focus Factor’s other products, aside from their children’s line and Focus Factor Brain & Vision, because there just aren’t enough differences to justify their increased costs.

And in the case of the company’s energy shots, they’re identical to 5 Hour Energy and Monster drinks, which are significantly more accessible from your nearest gas station or vending machine, whereas Focus Factor isn’t sold in stores.

You can learn more about Focus Factor — including a full product breakdown — in our review.

Here’s a look at the company’s lineup and costs, which come down with larger orders:

The Focus Factor Kids formula is extremely mild compared to the adult-oriented formula. We think this is a good thing, as children’s brains are still developing and are more susceptible to potential side effects.

The children’s formula includes the following in their nootropic blend:

• Bilberry (fruit)
• N-Acetyl L-Tyrosine
• Coenzyme Q10

The company has also added a new line of nootropic products in the last year, which are designed to work better for gamers. However, we still prefer their Original and Brain & Vision formulas; the nootropic formulas are closer to pre-workout and energy drinks than true nootropic supplements.

In the last year, Focus Factor has added free shipping to U.S. addresses for orders of $50 or more. If you don’t meet that $50 threshold, shipping from Focus Factor costs the following:

• Standard (5-7 days): $6.95
• Priority Mail (1-3 days): $14.95

Focus Factor doesn’t accept any returns unless your product arrives defective.

One of the coolest things that Focus Factor offers is the Brain Hub app. You can try it for free for seven days, and it provides you with guided meditations, a small audiobook library, mind and mood trackers, and a suite of five kinds of brain games (in focus, memory, math, problem-solving, and language) designed to keep you sharp and show how you’re progressing as you take their supplements. However, our testers only found two game categories actually fun (focus and problem-solving).

The app looks old and isn’t super intuitive, and we think there are better cognitive training apps on the market, but because this one is paired with Focus Factor and comes with a free trial, it’s worth it to give it a shot. Just be sure to cancel as soon as you can so you don’t accidentally get charged.

After your week-long free trial, you can pay for the Brain Hub app in the following ways:

• Monthly plan - $17.49/month
• Yearly plan - $59.99/year (saves you $149.89)
• Lifetime plan - $299.99 billed only once

Best range of products

• Huge range of nootropic supplements
• Supplements have a targeted focus
• Quiz is useful and not overly prescriptive
• Can shop by dietary restrictions
• Good learning resources
• Too many nuanced options for some users
• Generalized nootropics are very expensive
• Some supplements use up to 10 capsules per serving

BrainMD offers both comprehensive nootropics like Brain & Body Power and more targeted combinations like Calm My Brain. The latter supplement provides only magnesium and ashwagandha, whereas Brain & Body Power boasts more than 40 ingredients. Generally speaking, products with shorter ingredient lists tend to be higher in quality — with doses more in line with scientific research — than products like Brain & Body Power that contain dozens of ingredients. The company’s more targeted supplements tend to deliver higher doses of specific ingredients, and their more comprehensive offerings have relatively low doses of each component. It’s a great brand if you know you’ll want to shop around and try a few different kinds of supplements for your cognitive health.

It can be difficult to know which of the company’s vast array of products you should take, so they offer a short quiz about your lifestyle and cognitive performance. After the quiz, an algorithm will identify yours as one of 16 brain types. The site then lets you shop by your brain type to see only the supplements that would provide you with the biggest potential benefit. It’s more comprehensive and less prescriptive than Thesis’ quiz, which is better for people who want a more hands-on approach to their supplement journey.

BrainMD’s prices vary widely depending on their ingredient lists (as do the products’ efficacy). Subscribing is a good way to save, as you’ll take 15% off your order, but the company’s supplements are a bit expensive for what they offer. They aren’t as high-priced as TruBrain’s Clockwise or Qualia Mind, but they also don’t generally have the same first-time saving discounts. Instead, you can bundle both subscription and bulk deals for extra savings, like Focus Factor.

Here’s a look at a few of their most popular supplements:

Previously, all seven of these supplements were available as part of a free trial program . Now, they only offer Put Me To Sleep Naturally, Happy Saffron Plus (which is one of our top picks for the best saffron supplement ), Brain & Body Power, and Serotonin Mood Support, but you can still try any one of them for free for up to 14 days. After that, BrainMD will automatically enroll you in a subscription program for that supplement at the products’ standard cost.

Shipping with any subscription order is free, and non-subscription orders cost a flat $7.95 unless you order at least $75.

Hunter Focus

• Well-designed nootropic ingredient combination
• Free shipping on bulk orders
• Buy three bottles, get one free
• Part of a three-supplement plan
• Large serving size (six capsules)

Hunter Focus is the nootropic component of Hunter’s supplement system. Much like Onnit’s range of products, the company’s system includes Hunter Burn, a thermogenic fat burner, and Hunter Test, a natural testosterone booster.

Hunter Focus is a relatively straightforward supplement. It contains many of the most popular nootropic ingredients in relatively high doses. Here’s a brief look at some of their most effective ingredients:

• Acetyl-L-Carnitine (800mg)
• L-Tyrosine (500mg)
• Lion’s mane (500mg)
• Bacopa (300mg)
• Ashwagandha (300mg)
• Citicoline (300mg)
• Maritime pine bark extract (75mg)

All told, Hunter Focus contains 20 active ingredients that can directly or indirectly improve cognition, memory, and mood. This nootropic is very similar to Mind Lab Pro but contains more ingredients at slightly higher doses. Some of these ingredients are likely to bring positive benefits — ashwagandha root and ginseng, for example — while others are still on the newer side in research, such as Spanish sage. Hunter Focus contains 100mg of caffeine, so it’s not a good option for people who want a stimulant-free nootropic. (100mg is about what you’ll get in a cup of coffee and is very typical to find in nootropics that have caffeine.)

Between the two, we think Mind Lab Pro will be better for more people because some of Hunter Focus’ ingredients may inadvertently cancel each other out or cause strange side effects. Combining ashwagandha and caffeine may cause a particularly complicated response, for example. However, there’s nothing that stands out as harmful or otherwise strange in this supplement, so it is still a solid option.

Hunter Focus doesn’t offer any subscriptions, but you can save a little bit by buying in bulk (though comparatively much less than other products that offer bulk savings). Here’s how Hunter Focus’ pricing works out:

• One bottle: $90
• Two bottles: $180
• Three bottles (plus one free): $270

You’ll get free shipping as long as you buy two or more bottles at a time. Shipping for one bottle costs $7.95. Hunter has some of the widest-reaching international shipping options available with depots in London and Tennessee, and they can ship to all but 17 countries. If you don’t like Hunter Focus, you can return your bottle, opened or unopened, within 30 days of delivery; just reach out to their customer service team with your name, email, and order number, and tell them you’d like to return your bottle of Hunter Focus (and why) to get the ball rolling.

Qualia Mind

• Transparent formulation
• Large B vitamin doses
• Contains several well-regarded ingredients
• Steep discount on first subscription delivery
• 100-day money-back guarantee
• Non-stimulant option available
• Particularly expensive
• Most ingredients are underdosed
• Several ingredients lack clinical backing
• Take seven capsules daily for a full dose

These ingredients include:

• Vitamin B12
• Pantothenic acid
• Acetyl-L-Carnitine HCL
• Artichoke leaf extract
• Bacopa monnieri extract
• Rhodiola rosea extract
• DL-Phenylalanine
• Uridine-5’-monophosphate
• Whole coffee fruit extract
• Velvet bean seed extract
• Celastrus paniculatus seed extract
• Ginkgo biloba leaf extract
• Coleus forskohlii root extract
• Pyrroloquinoline quinone
• Huperzia serrata

It’s also important to note that Qualia Mind is generally underdosed in these ingredients compared to clinical studies. You could make the argument that we don’t know if the ingredients can all boost each other to sufficient efficacy, but we’d have to turn to the self-funded study on Qualia Mind to determine that. This study was thorough and clinically run, but after measuring six major cognitive performance aspects (executive function, attention and focus, inspiration, perceived stress, work engagement, and mindfulness) as well as self-reported sleep quality, immune health, productivity, and mood, researchers found that there was little difference between Qualia Mind and a placebo.

While it’s a relatively safe and very well-tested supplement, Qualia Mind isn’t going to be the best option for someone who’s just getting started with nootropics. If you don’t mind taking a lot of pills and are looking for a generalized nootropic with focus- and attention-boosting potential but are sensitive to high ingredient doses, Qualia Mind may be a good fit for you.

Learn more about Qualia Mind’s ingredients in depth in our full review .

Neurohacker Collective offers steep sales on all products when you start a subscription program. You can save $100 by ordering Qualia Mind as a subscription once and then canceling your subscription rather than purchasing a single bottle one time.

Here’s a closer look at Neurohacker Collective’s nootropic lineup:

The company used to offer free shipping on most orders but now charges either $7.98 for standard shipping (3-5 days) or $12.98 for priority shipping (2-3 days), only to a restricted list of English-speaking countries. Or, if you order from a third party, you’re more likely to get a now-extinct product called Qualia Mind Essentials, which comes in smaller sizes and has a shorter ingredient list. For the greatest chance of effectiveness, we recommend purchasing from the Neurohacker Collective website specifically.

Neurohacker Collective has one of the longest money-back guarantees in its category, offering users 100 days to see if the product works (and you’ll still get a refund if you open the bottle and test it). But a closer look reveals downsides here:

• The refund will only apply to your initial order or the most recent order within a subscription. You could start a subscription and ask for a refund on day 99, but you’ll only get a refund for whatever was part of that last month’s order.
• Your entire household will only be eligible once. This means you won’t be able to access a refund if someone in your household happened to try Qualia Mind in the past and returned it.

Onnit Alpha BRAIN

• Company has a focus on fitness
• Liquid nootropic shots available
• 90-day money-back guarantee
• Military discount available
• Limited dosage information
• Free shipping only on orders over $150

Onnit is a full-scale fitness brand offering everything from nutritional supplements to workout equipment. They have four Alpha BRAIN nootropic products that are caffeine-, dairy-, nut-, and gluten-free, as well as more than two dozen other supplements designed to optimize your health and wellness. We’ll focus mostly on their flagship product, Alpha BRAIN capsules, which also come in a Black Label version (with clearer dosage information, albeit a dissimilar ingredient list), an Instant powder, and Focus Shots, which are premixed caffeine shots with other nootropic ingredients.

Alpha BRAIN has a decent ingredient list as far as nootropics go, with a big focus on boosting your acetylcholine levels as much as possible (which may lead to things like intense lucid dreaming. and requires a strict cycling routine). 57 However, most of these ingredients are hidden behind a few proprietary blends, meaning Onnit provides the measurement of blend per serving but not each individual ingredient. While it’s used to keep competitors from copying an exact formula, it also keeps you from understanding what you’re actually taking. Onnit does well with testing measures, but the lack of greater transparency is a disappointment for Alpha BRAIN’s overall safety measures. Proprietary blends make it difficult to determine what side effects you’ll be more likely to experience, if any. And while proprietary blends are sadly not uncommon in nootropics (and Alpha BRAIN isn’t the worst offender, at least breaking down their blend into three separate smaller blends), it isn’t something that gives us confidence.

Alpha BRAIN has been subject to two scientific studies with mixed results, though they both found some evidence that Alpha BRAIN improved verbal memory scores. If you’re looking to improve learning and memory overall with a special focus on being able to restate what you know and are able to track a cycling schedule, this might be a good option for you.

You can learn more about Alpha BRAIN and its specific ingredient breakdown in our full review .

Alpha BRAIN pricing

Onnit Alpha BRAIN supplements come in various quantities, with larger orders offering impressive savings. Here’s a look at how their four nootropics price out:

A 30-count bottle of Alpha BRAIN is the only option where you can get a bulk discount. If you buy two bottles, you’ll save 25% ($26.22/bottle, or $52.43 total), and if you order three bottles, you’ll save 30% ($24.47/bottle, or $73.40 total). Both bulk deals give you a free copy of Joe Rogan’s seven-page eBook on his life philosophy and workout routine, but you shouldn’t let the free gift sway you — you can find the PDF for free elsewhere on the Onnit site.

You can also get a 15% discount as a member of the military, first responder, or medical provider, though you’ll need to verify your identity at checkout with an ID the first time you want to use this discount.

Shipping from Onnit is free on orders over $150. Otherwise, shipping varies depending on your location; our testers found it averaged between $7 and $11.

If you know where to look, you can also get a free trial of Alpha BRAIN . Onnit will give you a 30-count bottle of Alpha BRAIN for just the cost of shipping and sales tax, though it’s slightly hidden on Alpha BRAIN’s webpage. Onnit also features the second-best return policy on our list with an extra twist — you have 90 days to return any bottles that are at least half-full for a full refund. If you ordered a 30-count bottle for your first purchase and didn’t love it, Onnit will give you a full refund for the bottle without asking you to return it within that same 90-day window.

Alternatives to nootropic supplements

Your brain is the control center of the rest of your body, but there’s a two-way connection. What you eat, how you sleep, and hundreds of other small decisions influence how well your brain works. Not every factor is something you can control — as much as we might like to, there’s no stopping aging — but there are still plenty of things you can control. Improving other areas of your health will also often improve your daily cognitive functioning.

Generally, we first recommend checking in on your daily habits (are you sleeping and eating enough? Are you getting time outside?) and making lifestyle changes if you’re otherwise healthy. Adding supplements like vitamins, minerals, and individual nootropic ingredients is also a good bet if you’re struggling without an identifiable cause — especially B and D vitamins, omega-3s, and ashwagandha. And if things don’t get better with nootropics, lifestyle changes, and other vitamins, we encourage you to reach out to your doctor. There may be a more serious underlying cause, and they’ll be able to point you in the right direction.

Supplements

Many of the individual ingredients in nootropics can be purchased on their own as supplements, like ashwagandha, ginseng, vitamins, and minerals, if you’re curious about how a particular supplement works but don’t want to commit to the full ingredient roster (or price) of a nootropic supplement. However, there are a few other kinds of supplements that improve common complaints also addressed by nootropics.

Fatigue can be hugely detrimental to your cognition, making it more difficult to think, recall memories, and convey ideas, and can dampen even great moods. It’s also a common symptom of multiple kinds of vitamin deficiencies — most notably vitamins B and D — so simply taking a vitamin (or multivitamin) supplement for energy can improve your cognition without having to turn to nootropics. (If you still want to try a nootropic but feel like a multivitamin may help you more, try Focus Factor Original.) Otherwise, vitamin supplements are cheaper and safer than nootropics. If a multivitamin isn’t the right step, you can also try a pre-workout supplement, which is designed for muscle building and exercise expansion, rich with amino acids and caffeine; they’re generally safer but less convenient to take, and they may not do much for you if you aren’t working out while you’re taking them.

Omega-3 — found in things like fish oil , algae, and walnuts — is one of the best things you can take for your brain as you get older. One large study in late 2022 found that even among people in their 40s, omega-3 intake correlated almost directly with brain health and structure, altered slightly by APOE genotype. 43 Omega-3 supplements are generally inexpensive and high-quality, as they’ve been around for a significant amount of time and are highly popular. If you aren’t thrilled about the possibility of dealing with fishy burps, NAD+ supplements improve mitochondrial functioning that wanes with age. Since NAD+ is closely linked to vitamin B3, these supplements are generally safer than the botanical blends in nootropics, though they aren’t necessarily less expensive, depending on the brand you choose. (We recommend Renue by Science’s NMN SL sublingual powder, which is easy to take and only about $32.)

However, we recommend not using Prevagen, another nootropic supplement advertised as the best for an aging brain. It only contains a small dose of vitamin D and apoaequorin, a protein found in bioluminescent jellyfish that binds to calcium, which some researchers think may lead to neuronal death in excess. Studies have shown that Prevagen just doesn’t really work. 44

For anxiety and depression

The best ingredients for anxiety and depression in a nootropic supplement are easy to find on their own. Ashwagandha and ginseng are likely to be your best bets, as they have some of the most reliable clinical backings for stress relief.

You may also find success with a GABA supplement , particularly if you struggle with anxiety. However, if you have low blood pressure, you shouldn’t take a GABA supplement. GABA effectively lowers blood pressure, which is situationally great (high anxiety can raise blood pressure, even if you don’t have hypertension), but it can be dangerous if your blood pressure is low at the outset. We think Thorne’s PharmaGABA is the best GABA supplement on the market because of its high efficacy and flexibility. It comes in two doses: 100mg, which will be better for low-level anxiety, and 250mg, which will be better for more moderate anxiety and insomnia.

There aren’t as many non-prescription options for depression as there are for anxiety, and most of them that do exist have some serious problems. 5-HTP, a precursor to serotonin, is one of the bigger names you’ll see, but we hesitate to recommend it because 5-HTP can be toxic, causing serotonin syndrome in high doses. Most studies seem to agree that 5-HTP can alleviate depression symptoms, but these studies are also small.

If you’re struggling with depression, don’t be afraid to reach out to your primary care provider. Most general practitioners will write prescriptions for common SSRI antidepressants like Zoloft, Prozac, and Celexa, so you don’t have to wait for a psychiatrist appointment.

Lifestyle changes

We know: this is the last thing you want to hear. But living through the last few years means you’ve likely picked up some bad habits, experienced extremely high stress levels, or changed your lifestyle completely. It’s worth re-examining your daily routine to find ways you can naturally improve factors that impact cognition. These steps may make a bigger difference for some people than others — it may be more practical to fix your sleep cycle as a college junior than as a new parent — but it’s always going to be faster, safer, and generally better to try making lifestyle changes first.

Getting your eight hours a night is critical for proper brain function. While the exact mechanisms of sleep are still elusive, one theory is that sleep helps “wash” your brain , and medical experts know that your risk of brain disease increases the more sleep debt you get into. And sleep debt is difficult to recover from — even missing just two hours a night during one work-week means you’ll need to sleep an additional ten hours just to catch back up to baseline. Sleep deprivation is also closely tied to poor mental health outcomes and worse higher-level cognitive abilities. 45

Some people find they experience sharper cognition when they eat fewer calories, closer to their basal metabolic rate. Others find they aren’t actually eating enough, and eating more improves their capacity. Researchers have found that people suffering from anorexia nervosa who are underweight have diminished sensorimotor speeds and struggle with forgetting long-term memories, which improve with recovery and weight gain. 46 Different foods can make an impact on our cognitive states, too; our brains need healthy amounts of carbohydrates, protein, and healthy fats in order to function at full capacity.

According to a 2020 meta-analysis, long sessions of coordinated exercises — such as yoga, tai chi, and pilates — are the most beneficial for our brains, particularly if you’re male. 47 The length of time you’re exercising is important here, as longer exercise routines require you to practice your planning, concentration, and willpower abilities, which strengthen the brain beyond the other healthy effects of exercise. 48 The neural benefits of exercise are even greater for people with mild cognitive impairments, as evidenced by a study that also found lower levels of depression and better sleep quality. 49

Psychological researchers agree: touching grass really can make a big difference in your mental health. Exposure to natural settings improves participants’ working memory, cognitive flexibility, and attentional control more than exposure to urban centers, likely due to our long-standing evolutionary ties to natural settings. 50 Even things like air pollution and city noise can decrease your focus and general psychological functioning over time. 51 Spending a few hours in spaces rich in green — whether it’s your backyard, a forest on a long hike — or kayaking down a river can help reset your brain and improve your cognition.

The harmful effects of blue light on our sleep are well established. Sunlight is blue light, and so is the kind that emanates from our screens. Your brain uses blue light to regulate your internal clock; getting too much blue light disrupts your natural melatonin production, making it more difficult to sleep and causing sleep loss, which dramatically affects cognition. Using blue light filters (built into iPhones and with downloadable programs for computers) and wearing blue light glasses can help diminish blue light’s effects, but minimizing screen time — especially in the two hours before bedtime — makes the biggest difference.

Our testers all listen to music regularly while they work and find it makes a big difference in their ability to focus. Studies generally agree: background music improves attention scores, with a few caveats. The best music to listen to if you want to improve your attention is generally low-energy music without lyrics that you already know. 52 53 Genre doesn’t matter, but anything that you dislike — or enjoy — too much can be distracting. 54 Both scientists and musicians are picking up on this, and new concepts like binaural beats (providing slightly different tones to each ear in stereo) are starting to pop up, but note that familiarity is still one of the most important parts that makes music effective. 55

Focus Factor had the right idea when the company decided to release a cognitive training and diary app alongside supplements. Cognitive training through electronic games has been around as long as the technology it runs on, and many companies make huge claims about what their apps can help with (including things like ADHD, PTSD, Alzheimer’s, and dementia). However, a 2017 meta-analysis looking at almost 8,000 studies found only two brain training programs had more than one study in their favor (BrainHQ and CogniFit), and there’s no evidence to support them as a preventative or treatment strategy. 56 Ultimately, playing brain games won’t make a huge difference in your cognition, but it can help you flex some skills better than another round of Candy Crush.

See a doctor

Whether you’re struggling with mild depression or the signs of early dementia, nootropics might help, but they aren’t a cure. We always recommend talking to a doctor before trying any supplements, especially nootropics, as there may be an underlying cause for your brain fog that needs to be professionally treated.

Depending on your experiences, you may be given:

• Stimulants like Adderall or Ritalin
• Dopaminergic medications like L-Dopa
• Antidepressants like Paxil
• Anti-anxiety medications like Xanax
• Sleep medications like Ambien

It can be difficult to identify the root cause of cognitive issues because it’s a symptom of hundreds of different conditions, so checking in with a medical professional might help you catch something like hypothyroidism or anemia or, more seriously, something like MS or early-onset Alzheimer’s. You could also be experiencing a vitamin B12 deficiency, depression, or long COVID. A doctor will be able to look at your particular cognitive struggles and give you tests to identify the specific underlying problem. (Again, a nootropic supplement cannot, and will not ever, give a diagnosis, nor will it cure or prevent medical concerns.)

Nootropics FAQ

.css-1ygl3x{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;width:100%;outline:2px solid transparent;outline-offset:2px;transition-property:var(--chakra-transition-property-common);transition-duration:var(--chakra-transition-duration-normal);font-size:1rem;-webkit-padding-start:var(--chakra-space-4);padding-inline-start:var(--chakra-space-4);-webkit-padding-end:var(--chakra-space-4);padding-inline-end:var(--chakra-space-4);padding-top:var(--chakra-space-2);padding-bottom:var(--chakra-space-2);}.css-1ygl3x:focus,.css-1ygl3x[data-focus]{box-shadow:var(--chakra-shadows-outline);}.css-1ygl3x:hover,.css-1ygl3x[data-hover]{background:var(--chakra-colors-blackalpha-50);}.css-1ygl3x[disabled],.css-1ygl3x[aria-disabled=true],.css-1ygl3x[data-disabled]{opacity:0.4;cursor:not-allowed;} .css-1eziwv{-webkit-flex:1;-ms-flex:1;flex:1;text-align:left;} do nootropics permanently change your brain .css-1eok0x8{width:1em;height:1em;display:inline-block;line-height:1em;-webkit-flex-shrink:0;-ms-flex-negative:0;flex-shrink:0;color:#e22c3e;opacity:1;-webkit-transition:-webkit-transform 0.2s;transition:transform 0.2s;transform-origin:center;font-size:1.25em;vertical-align:middle;}.

No. Like any other supplement, when you stop taking a nootropic, you’ll stop seeing its effects. This doesn’t mean that you’ll lose access to new memories you’ve made, but any cognitive benefits you’ve gained will revert back to how your brain was functioning pre-nootropic. Most studies suggest that it takes 4-6 weeks of consistent use to reach a nootropic’s full potential. Studies also suggest that the effects slowly wear off over the course of one month after stopping if you’ve been taking them for at least six weeks. You can always go back on a nootropic after you’ve stopped taking it, too.

Can nootropics make me smarter?

Taking a nootropic doesn’t mean you’ll wake up a genius after a few weeks (or days). Nootropics can help you stay focused and improve your memory recall abilities, which may make studying easier or help you remember what you learned on your latest Wikipedia deep-dive. But you’ll still have to put in the effort to learn new facts and skills.

Can nootropics treat my ADHD?

Nootropic supplements aren’t a replacement for prescription medications. As a supplement, it’s against the FDA’s rules to state that they can treat or cure (or diagnose, prevent, or mitigate) any diseases and disorders, including those related to your cognitive health like ADHD or Alzheimer’s disease, no matter how mild they are. Nootropics may improve aspects of your cognitive performance, and some ingredients show promise in clinical studies by improving the quality of life of people with dementia, but nothing is proven or guaranteed. If you’re struggling with your mental health, we strongly recommend reaching out to a psychiatrist or your general physician first.

Is it possible to build your own nootropic?

Not only is it possible, but many people prefer building their own nootropics from individual ingredients. This is called building a “stack,” or a combination of ingredients much like one you’d find in a traditional nootropic supplement. There are pros and cons to this strategy.

On the negative side:

• You’d have to do the research to determine the proper dose.
• This approach sometimes involves swallowing many pills.
• Your safety isn’t as guaranteed as it is with a trusted nootropic manufacturer who’s done the right testing or formulated its product with proper caution and respect for what clinical studies have shown.

But it does mean you can choose to take only the ingredients that work well for you, which is always a good approach. Since it can be a little tricky to identify what does and doesn’t work, we recommend finding single-ingredient supplements from trusted manufacturers like Nootropic Depot through companies like iHerb, where you can order all of your ingredients in one place.

How do you pronounce “nootropic” anyway?

The term nootropic comes from two Greek words: nous , meaning mind or intelligence, and tropikos , meaning turning or changing. (That means that nootropic roughly translates to “mind-changing.”) Noo - sounds like “new,” and -tropic would rhyme with “toe-pick.”

Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Nootropics market size global report, 2022 - 2030 . Polaris Market Research: Global Market Research Reports and Consulting. (n.d.). Retrieved January 3, 2023.

Leuner, K., Kurz, C., Guidetti, G., Orgogozo, J., & Müller, W. E. (2010). Improved mitochondrial function in brain aging and Alzheimer disease - the new mechanism of action of the old metabolic enhancer piracetam . Frontiers in Neuroscience, 4 .

Cohen, P. A., Zakharevich, I., & Gerona, R. (2020). Presence of Piracetam in Cognitive Enhancement Dietary Supplements . JAMA Internal Medicine, 180 (3), 458-459.

Parker, A. G., Byars, A., Purpura, M., & Jäger, R. (2014). The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility . Journal of the International Society of Sports Nutrition, 12 (Suppl 1), P41.

Nakazaki, E., Mah, E., Sanoshy, K., Citrolo, D., & Watanabe, F. (2021). Citicoline and memory function in healthy older adults: A randomized, double-blind, placebo-controlled clinical trial . The Journal of Nutrition, 151 (8), 2153-2160.

Secades, J. J. (2019) Citicoline in the treatment of cognitive impairment . Journal of Neurology and Experimental Neuroscience, 5 (1), 14-26.

Lopresti, A. L., Smith, S. J., & Drummond, P. D. (2021). Modulation of the hypothalamic-pituitary-adrenal (HPA) axis by plants and phytonutrients: A systematic review of human trials . Nutritional Neuroscience, 25 (8), 1704-1730.

Lopresti, A. L., Smith, S. J., Malvi, H., & Kodgule, R. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study . Medicine, 98 (37).

Deshpande, A., Irani, N., Balkrishnan, R., & Benny, I. R. (2020). A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults . Sleep Medicine, 72 , 28-36.

Ng, Q. X., Loke, W., Foo, N. X., Tan, W. J., Chan, H. W., Lim, D. Y., & Yeo, W. S. (2019). A systematic review of the clinical use of Withania somnifera (ashwagandha) to ameliorate cognitive dysfunction . Phytotherapy Research, 34 (3), 583-590.

Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive flexibility: Evidence from proactive vs. reactive control during task switching performance . Neuropsychologia, 69 , 50-55.

Jongkees, B. J., Hommel, B., Kühn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands—A review . Journal of Psychiatric Research, 70 , 50-57.

Repantis, D., Bovy, L., Ohla, K., Kühn, S., & Dresler, M. (2021). Cognitive enhancement effects of stimulants: A randomized controlled trial testing methylphenidate, modafinil, and caffeine . Psychopharmacology, 238 , 441-451.

Yelanchezian, Y. M. M., Waldvogel, H. J., Faull, R. L. M., & Kwakowsky, A. (2022). Neuroprotective effect of caffeine in Alzheimer’s disease . Molecules, 27 (12), 3737.

Kimura, K., Ozeki, M., Juneja, L. R., & Ohira, H. (2007). L-Theanine reduces psychological and physiological stress responses . Biological Psychology, 74 (1), 39-45.

Hidese, S., Ogawa, S., Ota, M., Ishida, I., Yasukawa, Z., Ozeki, M., & Kunugi, H. (2019). Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: A randomized controlled trial . Nutrients, 11 (10), 2362.

Stojcheva, E. I., & Quintela, J. C. (2022). The effectiveness of Rhodiola rosea L. preparations in alleviating various aspects of life-stress symptoms and stress-induced conditions: Encouraging clinical evidence . Molecules, 27 (12), 3902.

Darbinyan, V., Kteyan, A., Panossian, A., Gabrielian, E., Wikman, G., & Wagner, H. (2000). Rhodiola rosea in stress induced fatigue — A double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty . Phytomedicine, 7 (5), 365-371.

Ma, G., Zheng, Q., Xu, M., Zhou, X., Lu, L., Li, Z., & Zheng, G. (2018). Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms . Frontiers in Pharmacology, 9 .

Kongkeaw, C., Dilokthornsakul, P., Thanarangsarit, P., Limpeanchob, N., & Norman Scholfield, C. (2014). Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract . Journal of Ethnopharmacology, 151 (1), 528-535.

Pase, M. P., Kean, J., Sarris, J., Neale, C., Scholey, A. B., & Stough, C. (2012). The cognitive-enhancing effects of Bacopa monnieri: A systematic review of randomized, controlled human clinical trials . The Journal of Alternative and Complementary Medicine, 18 (7), 647-652.

Bell, L., Whyte, A., Duysburgh, C., Marzorati, M., Van den Abbelle, P., Le Cozannet, R., Fança-Berthon, P., Fromentin, E.m & Williams, C. (2021). A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action . European Journal of Nutrition, 61 , 413-428.

Baek, J. H., Heo, J., Fava, M., Mischoulon, D., Choi, K. W., Na, E. J., Cho, H., & Jeon, H. J. (2019). Effect of Korean Red Ginseng in individuals exposed to high stress levels: A 6-week, double-blind, randomized, placebo-controlled trial . Journal of Ginseng Research, 43 (3), 402-407.

Reay, J. L., van Schaik, P., & Wilson, C. J. (2019). A systematic review of research investigating the physiological and psychological effects of combining Ginkgo biloba and Panax ginseng into a single treatment in humans: Implications for research design and analysis . Brain and Behavior, 9 (3).

Damar, U., Gersner, R., Johnstone, J. T., Schachter, S., & Rotenberg, A. (2017). Huperzine A: A promising anticonvulsant, disease modifying, and memory enhancing treatment option in Alzheimer’s disease . Medical Hypotheses, 99 , 57-62.

Fernstrom J. D. (1994). Dietary amino acids and brain function . Journal of the American Dietetic Association, 94 (1), 71–77.

Suzuki, H., Yamashiro, D., Ogawa, S., Kobayashi, M., Cho, D., Iizuka, A., Takada, M., Isokawa, M., Nagao, K., & Fujiwara, Y. (2020). Intake of Seven Essential Amino Acids Improves Cognitive Function and Psychological and Social Function in Middle-Aged and Older Adults: A Double-Blind, Randomized, Placebo-Controlled Trial . Frontiers in Nutrition, 7 .

Oregon State University. (2023, January 3). Micronutrient inadequacies in the US population: An overview . Linus Pauling Institute. Retrieved February 27, 2023.

El-Nashar, H. A. S., Abbas, H., Zewail, M., Noureldin, M. H., Ali, M. M., Shamaa, M. M., Khattab, M. A., & Ibrahim, N. (2022). Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer’s disease mouse model: Focus on antioxidant, anti-inflammatory, and amyloidogenic pathways . Pharmaceuticals, 15 (10), 1202.

Lewis, J. A., & Young, R. (1975). Deanol and methylphenidate in minimal brain dysfunction . Clinical pharmacology and therapeutics, 17 (5), 534–540.

Dos Santos Quaresma, M. V. L., Souza, W. Y. G., Lemos, V. A., Caris, A. V., & Thomatieli-Santos, R. V. (2020). The possible importance of glutamine supplementation to mood and cognition in hypoxia from high altitude . Nutrients, 12 (12), 3627.

Chen, C., Xia, S., He, J., Lu, G., Xie, Z., & Han, H. (2019). Roles of taurine in cognitive function of physiology, pathologies and toxication . Life Sciences, 231 , 116584.

Utley, A., Gonzalez, Y., Abbott, C., & Nykjaer, C. (2021). The efficacy of the nootropic supplement Mind Lab Pro on information processing and memory in adults: Pseudo randomised, double blind, placebo-controlled studies . University of Leeds.

Cognitive Research Corporation. (2011, August 19). Evaluation of a vitamin/nutraceutical formulation designed to support and maintain memory, concentration and focus in healthy adults .

Barringer, N., Crombie, A., & Kotwal, R. (2018). Impact of a purported nootropic supplementation on measures of mood, stress, and marksmanship performance in U.S. active duty soldiers . Journal of the International Society of Sports Nutrition, 15 (26).

Solomon, T. M., Leech, J., deBros, G. B., Murphy, C. A., Budson, A. E., Vassey, E. A., & Solomon, P. R. (2016). A randomized, double-blind, placebo controlled, parallel group, efficacy study of alpha BRAIN administered orally . Human Psychopharmacology: Clinical and Experimental, 31(2), 135-143.

Qualia Mind Study . Neurohacker Collective. (n.d.). Retrieved January 24, 2023.

Centers for Disease Control and Prevention. (2023, February 23). Therapeutic Drug Use . Centers for Disease Control and Prevention. Retrieved February 27, 2023.

Acosta, L., Byham-Gray, L., Kurzer, M., & Samavat, H. (2022). Hepatotoxicity with High-Dose Green Tea Extract: Effect of Catechol-O-Methyltransferase and Uridine 5'-Diphospho-glucuronosyltransferase 1A4 Genotypes . Journal of Dietary Supplements , 1–20. Advance online publication.

Volpi-Abadie, J., Kaye, A. M., & Kaye, A. D. (2013). Serotonin Syndrome . The Ochsner Journal, 13 (4), 533-540.

Hosenbocus, S., & Chahal, R. (2012). A Review of Executive Function Deficits and Pharmacological Management in Children and Adolescents . Journal of the Canadian Academy of Child and Adolescent Psychiatry, 21 (3), 223-229.

Hwang, J. S., & Shin, Y. J. (2021). Role of Choline in Ocular Diseases . International journal of molecular sciences, 22 (9), 4733.

Satizabal, C. L., Himali, J. J., Beiser, A. S., Ramachandran, V., van Lent, D. M., Himmali, D., Aparicio, H. J., Maillard, P., DeCarli, C. S., Harris, W. S., & Seshadri, S. (2022). Association of red blood cell omega-3 fatty acids with MRI markers and cognitive function in midlife . Neurology, 99(23), 2572-2582.

Lerner, K. C. (2016) Madison Memory Study: A randomized, double-blinded, placebo-controlled trial of apoaequorin in community-dwelling, older adults .

Killgore, W. D. (2010). Effects of sleep deprivation on cognition . Progress in Brain Research, 185 , 105-129.

Hatch, A., Madden, S., Kohn, M. R., Clarke, S., Touyz, S., Gordon, E., & Williams, L. M. (2009). In first presentation adolescent anorexia nervosa, do cognitive markers of underweight status change with weight gain following a refeeding intervention? International Journal of Eating Disorders, 43 (4), 295-306.

Ludyga, S., Gerber, M., Pühse, U., Looser, V. N., & Kamijo, K. (2020). Systematic review and meta-analysis investigating moderators of long-term effects of exercise on cognition in healthy individuals . Nature Human Behavior, 4 , 603-612.

Audiffren, M., & André, N. (2019). The exercise–cognition relationship: A virtuous circle . Journal of Sport and Health Science, 8 (4), 339-347.

Song, D., & Yu, D. S. (2019). Effects of a moderate-intensity aerobic exercise programme on the cognitive function and quality of life of community-dwelling elderly people with mild cognitive impairment: A randomised controlled trial . International Journal of Nursing Studies, 93 , 97-105.

Schertz, K. E., & Berman, M. G. (2019). Understanding Nature and Its Cognitive Benefits . Current Directions in Psychological Science .

Tzivian, L., Winkler, A., Dlugaj, M., Schikowski, T., Vossoughi, M., Fuks, K., Weinmayr, G., & Hoffmann, B. (2015). Effect of long-term outdoor air pollution and noise on cognitive and psychological functions in adults . International Journal of Hygiene and Environmental Health, 218 (1), 1-11.

Chou, P. T. (2010). Attention drainage effect: How background music effects concentration in Taiwanese college students . Journal of the Scholarship of Teaching and Learning, 10 (1), 36-46.

Shih, Y., Huang, R., & Chiang, H. (2012). Background music: Effects on attention and performance . Work, 42 (4), 573-578.

Huang, R. & Shih, Y. (2011). Effects of background music on concentration of workers . Work, 38 (4), 383-387.

Reedijk, S. A., Bolders, A., & Hommel, B. (2013). The impact of binaural beats on creativity . Frontiers in Human Neuroscience, 7 .

Shah, T. M., Weinborn, M., Verdile, G., Sohrabi, H. R., & Martins, R. N. (2017). Enhancing cognitive functioning in healthy older adults: A systematic review of the clinical significance of commercially available computerized cognitive training in preventing cognitive decline . Neuropsychology Review, 27 , 62-80.

Holzinger, B., & Mayer, L. (2020). Lucid Dreaming Brain Network Based on Tholey’s 7 Klartraum Criteria . Frontiers in Psychology, 11 .

No spam! Your privacy is important to us.

Copyright © Innerbody Research 1997 - 2024. All Rights Reserved.

Innerbody Research does not provide medical advice, diagnosis, or treatment. You must consult your own medical professional.

Victor Mukhin

• Scientific Program

Title : Active carbons as nanoporous materials for solving of environmental problems

However, up to now, the main carriers of catalytic additives have been mineral sorbents: silica gels, alumogels. This is obviously due to the fact that they consist of pure homogeneous components SiO2 and Al2O3, respectively. It is generally known that impurities, especially the ash elements, are catalytic poisons that reduce the effectiveness of the catalyst. Therefore, carbon sorbents with 5-15% by weight of ash elements in their composition are not used in the above mentioned technologies. However, in such an important field as a gas-mask technique, carbon sorbents (active carbons) are carriers of catalytic additives, providing effective protection of a person against any types of potent poisonous substances (PPS). In ESPE “JSC "Neorganika" there has been developed the technology of unique ashless spherical carbon carrier-catalysts by the method of liquid forming of furfural copolymers with subsequent gas-vapor activation, brand PAC. Active carbons PAC have 100% qualitative characteristics of the three main properties of carbon sorbents: strength - 100%, the proportion of sorbing pores in the pore space – 100%, purity - 100% (ash content is close to zero). A particularly outstanding feature of active PAC carbons is their uniquely high mechanical compressive strength of 740 ± 40 MPa, which is 3-7 times larger than that of  such materials as granite, quartzite, electric coal, and is comparable to the value for cast iron - 400-1000 MPa. This allows the PAC to operate under severe conditions in moving and fluidized beds.  Obviously, it is time to actively develop catalysts based on PAC sorbents for oil refining, petrochemicals, gas processing and various technologies of organic synthesis.

Victor M. Mukhin was born in 1946 in the town of Orsk, Russia. In 1970 he graduated the Technological Institute in Leningrad. Victor M. Mukhin was directed to work to the scientific-industrial organization "Neorganika" (Elektrostal, Moscow region) where he is working during 47 years, at present as the head of the laboratory of carbon sorbents.     Victor M. Mukhin defended a Ph. D. thesis and a doctoral thesis at the Mendeleev University of Chemical Technology of Russia (in 1979 and 1997 accordingly). Professor of Mendeleev University of Chemical Technology of Russia. Scientific interests: production, investigation and application of active carbons, technological and ecological carbon-adsorptive processes, environmental protection, production of ecologically clean food.   

Quick Links

• Conference Brochure
• Tentative Program

• Campus News
• Campus Events
• Devotionals and Forums
• Readers’ Forum
• Education Week
• Breaking News
• Police Beat
• Video of the Day
• Current Issue
• August 2023
• February 2023
• January 2023
• The Daily Universe Magazine, December 2022
• The Daily Universe, November 2022
• The Daily Universe Magazine, October 2022
• The Daily Universe Magazine, September 2022 (Black 14)
• The Daily Universe Magazine, March 2022
• The Daily Universe Magazine, February 2022
• The Daily Universe Magazine, January 2022
• December 2021
• The Daily Universe Magazine, November 2021
• The Daily Universe, October 2021
• The Daily Universe Magazine, September 2021
• Hope for Lahaina: Witnesses of the Maui Wildfires
• Auschwitz-Birkenau Memorial
• The Black 14: Healing Hearts and Feeding Souls
• Camino de Santiago
• A Poor Wayfaring Man
• Palmyra: 200 years after Moroni’s visits
• The Next Normal
• Called to Serve In A Pandemic
• The World Meets Our Campus
• Defining Moments of BYU Sports
• If Any of You Lack Wisdom

Eye on the Y: BYU graduate students speed-present research, BYU Young Company revamps Shakespeare, BYU bowling hosts March Madness Bowling Tournament

Byu graduate students speed-present research.

BYU graduate students participated in the 2024 Three Minute Thesis competition on Thursday, March 21. The competition originated at the University of Queensland in 2008 and has continued to spread to campuses worldwide. 

As the name suggests, graduate students who compete present their research in three minutes or less. Each department held its individual competition and sent its first place winner to the university-wide competition. Cash prizes were awarded to competitors. More information regarding the competition and its rules can be found here . 

First place winner Jared Steele from the College of Life Sciences took home $2,000 for his presentation, titled, “Leveraging SuperShoe Technology for Clinical Care.” Steele’s study addressed how SuperShoes can decrease the metabolic cost of those who begin walking again after operation or illness.

Second place winner Luke Taylor from the College of Engineering won $1,500 for his research: “Improving Medical Capsule Location.” Khiara Cardoza from the College of Family, Home and Social Sciences won third place and received $1,000 for her presentation on “Exploring Gender Differences in Infertility.”

BYU Young Company revamps Shakespeare

The Department of Theatre and Media Arts’ Young Company has taken the early 1600s Shakespeare classic, “The Tempest,” and reimagined it to appeal to younger audiences. The show will be performed in the West Campus Studio Theatre from April 3-5 and April 9-13.

The Young Company’s performance will tell the story of a betrayed wizard king and his daughter in a contemporary beach-crossroads setting with a variety of familiar characters.

Show director and BYU professor Teresa Dayley Love said the audience will be engaged and asked to participate, including making the sounds and motions of waves, wind, thunder and lightning. Because audience participation will be a vital component of the show, each performance will offer a slightly different storytelling experience.

The show will be free to attend. American Sign Language interpretation is available on April 11.

BYU bowling hosts March Madness Bowling Tournament

On March 23, the BYU Bowling and Games Center was heated with competition — BYU bowling’s third Annual March Madness Bowling Tournament was dubbed a success.

The tournament was open to all who wanted to participate, big-time-bowlers or not. The 32 players warmed up before the tournament at the open lanes and the competition commenced in single elimination bracket form. After being knocked out of the competition, participants were given the opportunity to continue bowling for the remaining time. 

First place winner Walker Thompson scored 235 points and won a Nike basketball signed by the entire BYU men’s basketball team. Parker Walters and Grant Nielson won second and third place respectively.

If you missed the tournament, the BYU Bowling and Games Center is open throughout the week for students, faculty and the public. 

RELATED ARTICLES MORE FROM AUTHOR

How to celebrate women’s history month, female students want more female professors as mentors, byu night at the museums event draws students, public to explore campus resources.

First refuelling for Russia’s Akademik Lomonosov floating NPP

!{Model.Description}

The FNPP includes two KLT-40S reactor units. In such reactors, nuclear fuel is not replaced in the same way as in standard NPPs – partial replacement of fuel once every 12-18 months. Instead, once every few years the entire reactor core is replaced with and a full load of fresh fuel.

The KLT-40S reactor cores have a number of advantages compared with standard NPPs. For the first time, a cassette core was used, which made it possible to increase the fuel cycle to 3-3.5 years before refuelling, and also reduce by one and a half times the fuel component in the cost of the electricity produced. The operating experience of the FNPP provided the basis for the design of the new series of nuclear icebreaker reactors (series 22220). Currently, three such icebreakers have been launched.

The Akademik Lomonosov was connected to the power grid in December 2019, and put into commercial operation in May 2020.

Electricity generation from the FNPP at the end of 2023 amounted to 194 GWh. The population of Pevek is just over 4,000 people. However, the plant can potentially provide electricity to a city with a population of up to 100,000. The FNPP solved two problems. Firstly, it replaced the retiring capacities of the Bilibino Nuclear Power Plant, which has been operating since 1974, as well as the Chaunskaya Thermal Power Plant, which is more than 70 years old. It also supplies power to the main mining enterprises located in western Chukotka. In September, a 490 km 110 kilovolt power transmission line was put into operation connecting Pevek and Bilibino.

Image courtesy of TVEL

• Terms and conditions
• Privacy Policy
• Newsletter sign up
• Digital Edition
• Editorial Standards

• Ingredients

blends tailored to your unique needs.

How can we help?

Month 1: what to expect, month 2+: what's next, quality control & manufacturing, shipping & orders.

What are nootropics and how can they help me?

Nootropics are nutrient compounds shown to support motivation, creativity, mood, memory, focus, and cognitive processing. They work best when combined with exercise, proper nutrition, and mindfulness activities such as meditation. One of the most commonly used and consumed nootropics is caffeine - but it is far from the most exciting!

Are nootropics safe?

Safety is our top priority. The FDA has guidelines on how to manufacture supplements, called Current Good Manufacturing Processes, or cGMP. All of our products are manufactured in the United States, in facilities that follow cGMP regulations and are regularly inspected by the FDA. We only use ingredients that are classified by the FDA as Generally Recognized As Safe (GRAS) or have passed through Phase III clinical trials. We also have all of our nutrients tested by a third party lab to ensure the utmost quality.

Why do I need personalized nootropics?

You're unique - and so is your brain chemistry! Our innovative Starter Kit allows each participant to experience multiple formulas and determine what works best for them. Our process is complex because we’ve found that it yields the best results in the shortest amount of time. If we could formulate one pill that would work for everyone, we would! Because the human brain is deeply complex, that is simply not possible.

Where can I find the ingredients and dosages in my blends?

After you take the quiz, your results page will display the recommended nutrients and dosages for your blends. Your blend boxes feature a full list of ingredients, dosages and the recommended use cases to make the most of your Thesis.

How do I adjust my blends?

The fastest way to select your blends is by logging in to your customer portal! You can also call us at 646-647-3599 or send an email to [email protected] and we can make adjustments for you!

Can I just buy all the ingredients and take them all at the same time?

Thesis exists to take the guesswork out of combining nootropics. Our supplements come pre-measured and pre-organized into daily packets. The key is to find the right nootropics in the right dosages to maximize results while avoiding unintended side-effects. We have data scientists hard at work figuring out the right mix for you.

Do you offer caffeine-free formulas?

Yes! Choose this option before you purchase or email us at [email protected] to switch to caffeine free.

How does the starter kit work?

1. Your starter kit includes 4 different blends. You will try one blend per week to see which blends match best with your personal neurochemistry. 2. Take your blend first thing in the morning, for 6 consecutive days with 1 day of break before moving on to the next blend. 3. Jot down notes on how each blend makes you feel. Some things to look out for are improvements in memory, alertness, mood, and productivity. 4. After you try all 4 blends, you will have a good idea as to which 1-2 blends are most effective for you. 5. Once you decide, log in to your customer portal to select your favorite blends!

Should I take the nootropics on an empty stomach or with food?

Thesis can be taken with or without food. The effects of nootropics are strongest when taken on an empty stomach, but for those with sensitivities, try taking Thesis with food.

How long will it take before I start to get results?

Many users start to feel the effects within 30 minutes. There are some Thesis blends that will take a few days to ramp up. It varies based on your digestion and experience with nootropics. If your body ends up requiring a loading phase, don’t get discouraged. Stay with the program and the benefits will come.

What happens if I don’t like parts of my personalized formula?

This is completely normal, and a part of the optimization process. If you don’t like any of the blends in your box, let us know and we’ll switch it for something that’s a better fit for your lifestyle, genetics and goals. Give us a call at 646-647-3599 or send an email to [email protected] to customize your blends!

Will I experience side effects?

Thesis was developed to find which nootropics work for each individual. A way that your body tells you that a certain compound may not be ideal is by activating an undesired effect. If you experience a prolonged headache or uneasy stomach, we’ve identified a sub-optimal nootropic blend. Stop taking it. Finding what doesn’t work can be just as productive as finding what does. Based on feedback from thousands of customers, the cases of side effects are rare.

Can I still drink coffee?

Certainly! But you might find that you don’t need to anymore. Users have reported an ability to significantly cut coffee consumption with the use of nootropics.

I finished the starter kit. What's next?

Once you have determined which 1-2 blends work most effectively for you, you have a lot more flexibility in terms of how you take it! You can still stick to one blend per week, or you can switch up your blends for different days, situations, and times. The following months focus on fine tuning how your selected blends impact you and in what way, so you may find some blends work better for certain situations than others.

Can I try blends that were not included in my starter kit?

Absolutely! There are a total of 6 blends, so month 2 is the perfect time to try the other 2 blends you did not receive. To make blend adjustments, log in to your customer portal or send an email to [email protected]. If you decide to try a new blend, remember to stick to that blend for 6 consecutive days to see if it matches with your neurochemistry.

How often can I take my nootropics?

Thesis is designed for daily use. As a best practice, we recommend that you take a day off each week so that you know where your baseline is. While there is no detriment to efficacy, it's important to understand how a day feels without nootropics so you can appreciate the effects fully.

Can I take more than 1 packet a day?

While our blends are ideal for 4-6 hours of steady focus, it is perfectly safe to take up to 2 blends per day, at least 4 hours apart. For optimal results, take 1 blend upon waking and the next around when you have lunch. Don't take more than 2 packets in a 24 hour period - rest is important!

Do benefits continue even after I stop taking the nootropics?

Some of our nutrients are neuroprotective. Our ingredients increase Brain-Derived Neurotrophic Factor (BDNF), which promotes the growth of new neurons and synapses in the brain. A full list of our ingredients and their benefits can be found on the Ingredients page of our site, linked on the top and bottom of this page.

Are there any long-term side effects?

In clinical trials, none of the ingredients we include in our blends show long-term side effects. In fact, nootropics actually become more effective over time due to the continuous buildup of nutrients in your system!

Where do you source your products?

All our products are sourced from reputable vendors in the United States. Our capsules are manufactured in facilities that meet FDA requirements and go through rigorous independent lab testing.

How do I know your ingredients are pure?

All of our ingredients are tested for purity by third party labs.

Dietary concerns?

Thesis is vegan, and made without gluten, eggs or nuts. Some of our manufacturing facilities may also process products that contain gluten, nuts or eggs. We’ve taken precautions to protect against cross contamination but our product is not certified vegan or gluten free. If you have a specific dietary restriction or concern, let us know so we can make sure you receive the appropriate blends!

How long does it take to arrive?

We ship orders same-day whenever possible, or by the next business day after purchase. Transit is faster the closer you are to us here in NYC, and packages generally arrive 3-7 business days after purchase.

Do you ship internationally?

This is something we would like to offer, but logistics have been tricky this past year! Thesis is only available domestically at the moment – but will extend to our international neighbors as soon as possible. Stay tuned!

I put in the wrong information in my order! How can I fix it?

We’ve got your back – send us the correct info and we can make any necessary changes! We are available daily: [email protected]

Do you offer refunds?

Yes! We'll do our best to help you find the blends that work best for you, so that you can achieve your goals. If you aren't satisfied with Thesis, let us know. You can check out our full return policy by clicking the link at the bottom of the page.

What is your cancellation policy for subscriptions?

You can cancel your subscription anytime. Simply send us an email at [email protected], and we’ll take care of the rest!

Will I be charged automatically every month?

It depends on which option you select at checkout: Thesis can be purchased as either a one-time order or a monthly subscription. We offer a discount for subscriptions because it helps us with inventory management. If you choose a subscription, we will reach out to you via email ahead of any shipments. If you'd like to to adjust the cadence of your deliveries, the blends we’re sending or make any changes, just let us know!

I have a hard time swallowing capsules, can I open the capsules and pour their contents into water?

You could, but we don’t recommend it – the ingredients inside our capsules taste bad, which is why we have them encapsulated!

Why do I have to take so many pills?

Each packet contains 2-4 pills. We know it’s not always easy to swallow that many pills, but each is concentrated and has a specific purpose.

Do you offer free samples? I don’t want to pay and find out I don’t like it.

We don’t offer free samples anymore (too many freeloaders on the internet 😜). But we do offer a no-questions-asked refund policy on your first box of Thesis!

What happens to my data?

We never share any of your personal identifying information with anyone, EVER. In the future, we hope to use your detailed feedback to move the field of brain health forward.

Didn’t find what you were looking for? You can always call or email.

[email protected]

1-646-647-3599

Stop procrastinating

Stop Procrastinating

Personalized nootropic formulas to activate every kind of brain.

Rosatom Starts Production of Rare-Earth Magnets for Wind Power Generation

TVEL Fuel Company of Rosatom has started gradual localization of rare-earth magnets manufacturing for wind power plants generators. The first sets of magnets have been manufactured and shipped to the customer.

In total, the contract between Elemash Magnit LLC (an enterprise of TVEL Fuel Company of Rosatom in Elektrostal, Moscow region) and Red Wind B.V. (a joint venture of NovaWind JSC and the Dutch company Lagerwey) foresees manufacturing and supply over 200 sets of magnets. One set is designed to produce one power generator.

“The project includes gradual localization of magnets manufacturing in Russia, decreasing dependence on imports. We consider production of magnets as a promising sector for TVEL’s metallurgical business development. In this regard, our company does have the relevant research and technological expertise for creation of Russia’s first large-scale full cycle production of permanent rare-earth magnets,” commented Natalia Nikipelova, President of TVEL JSC.

“NovaWind, as the nuclear industry integrator for wind power projects, not only made-up an efficient supply chain, but also contributed to the development of inter-divisional cooperation and new expertise of Rosatom enterprises. TVEL has mastered a unique technology for the production of magnets for wind turbine generators. These technologies will be undoubtedly in demand in other areas as well,” noted Alexander Korchagin, Director General of NovaWind JSC.

For reference:

TVEL Fuel Company of Rosatom incorporates enterprises for the fabrication of nuclear fuel, conversion and enrichment of uranium, production of gas centrifuges, as well as research and design organizations. It is the only supplier of nuclear fuel for Russian nuclear power plants. TVEL Fuel Company of Rosatom provides nuclear fuel for 73 power reactors in 13 countries worldwide, research reactors in eight countries, as well as transport reactors of the Russian nuclear fleet. Every sixth power reactor in the world operates on fuel manufactured by TVEL. www.tvel.ru

NovaWind JSC is a division of Rosatom; its primary objective is to consolidate the State Corporation's efforts in advanced segments and technological platforms of the electric power sector. The company was founded in 2017. NovaWind consolidates all of the Rosatom’s wind energy assets – from design and construction to power engineering and operation of wind farms.

Overall, by 2023, enterprises operating under the management of NovaWind JSC, will install 1 GW of wind farms. http://novawind.ru

Elemash Magnit LLC is a subsidiary of Kovrov Mechanical Plant (an enterprise of the TVEL Fuel Company of Rosatom) and its main supplier of magnets for production of gas centrifuges. The company also produces magnets for other industries, in particular, for the automotive

industry. The production facilities of Elemash Magnit LLC are located in the city of Elektrostal, Moscow Region, at the site of Elemash Machine-Building Plant (a nuclear fuel fabrication facility of TVEL Fuel Company).

Rosatom is a global actor on the world’s nuclear technology market. Its leading edge stems from a number of competitive strengths, one of which is assets and competences at hand in all nuclear segments. Rosatom incorporates companies from all stages of the technological chain, such as uranium mining and enrichment, nuclear fuel fabrication, equipment manufacture and engineering, operation of nuclear power plants, and management of spent nuclear fuel and nuclear waste. Nowadays, Rosatom brings together about 350 enterprises and organizations with the workforce above 250 K. https://rosatom.ru/en/

U.S. Added Less New Wind Power in 2021 Than the Previous Year — Here’s Why

Norway’s Massive Floating Wind Turbine Wall Will Be Funded by the Government This Year

Top 10 Countries in Wind Energy Capacity

RWE Becomes a Top Tier Renewable Energy Company in the United States

Highest Self-Supported Wind Tower Ever Built

EGYPT: West Bakr Wind Farm goes into Operation After Nearly 2 Years of Construction