COMMENTS

  1. Case Examples

    Sara, a 35-year-old married female. Sara was referred to treatment after having a stillbirth. Sara showed symptoms of grief, or complicated bereavement, and was diagnosed with major depression, recurrent. The clinician recommended interpersonal psychotherapy (IPT) for a duration of 12 weeks. Bleiberg, K.L., & Markowitz, J.C. (2008).

  2. Understanding Depression: Real-life Mental Health Case Study

    Sarah's case study highlights several important lessons about depression and its treatment: 1. Early intervention is crucial: Sarah's initial reluctance to seek help led to a prolongation of her symptoms. Recognizing and addressing mental health concerns early can prevent the condition from worsening. 2.

  3. A case of treatment-resistant depression in an older adult and a

    A case of treatment-resistant depression in an older adult and a discussion of treatment options - Volume 46 Issue 6 ... McKean, MacMaster and Clement 1 If the first definition is used, the sequenced treatment alternatives to relieve depression study (STAR*D trial) ... Given that TRD is a chronic condition, thought also needs to be given to how ...

  4. Major depressive disorder: Validated treatments and future challenges

    Depression is a common psychiatric disorder and a major contributor to the global burden of diseases. According to the World Health Organization, depression is the second-leading cause of disability in the world and is projected to rank first by 2030 [1]. Depression is also associated with high rates of suicidal behavior and mortality [2].

  5. Understanding the Relationship between Depression and Chronic Diseases

    1.1. Mechanisms of Influence: Chronic Diseases → Depression. The first and most important factor that could explain how chronic illness causes or exacerbates depression is the burden of suffering from the condition and its impact on people's quality of life [5,6,7,9,10,11].Being diagnosed as diabetic or chronically ill often has a strong impact on patients beyond the physiological effects ...

  6. Case study: Chronic depression.

    Colleen was a 35-year-old married Caucasian woman who was referred by her psychiatrist for the treatment of chronic, recurrent depression. She had been on disability for approximately 1 year; previously, she had been completing the final requirements of her schooling to become a clinical social worker. She reported a history of depression that began when she was a teenager, and she indicated ...

  7. Cognitive Behavioral Therapy for Depression

    A meta-analysis of 115 studies has shown that CBT is an effective treatment strategy for depression and combined treatment with pharmacotherapy is significantly more effective than pharmacotherapy alone. ... Chronic depression and recurrent depression: CBT or medication: ... Case conceptualization for the cognitive model of depression.

  8. Schema Therapy for Chronic Depression Associated with Childhood Trauma

    ST has been studied in patients with chronic depression with good results. The purpose of this case study is to detail how an ST treatment was used to treat chronic depression in a woman, "Amy," with a childhood trauma history. Amy presented with a persistent depressive disorder that had lasted over 40 years.

  9. Schema therapy for chronic depression: Results of a multiple single

    Many patients with chronic depression do not improve in current pharmacological or psychological treatments for depression highlighting the need of exploring new treatment options for this patient group. The aim of this study was to test the effects of individual schema therapy (ST) in a case-series of 25 patients with chronic depression.

  10. Schema therapy for patients with chronic depression: a single case

    Methods: Twelve patients with a diagnosis of chronic depression participated. The treatment protocol consisted of 60 sessions, with the first 55 sessions offered weekly and the last five sessions on a biweekly basis. A single case series A-B-C design, with 6 months follow-up was used. Baseline (A) was a wait period of 8 weeks.

  11. Patient-led integrated cognitive behavioural therapy for ...

    This case illustrates the effective use of patient-led CBT for managing symptoms of long COVID with comorbid depression and anxiety in primary care. ... A case study Chronic Illn. 2022 Sep;18(3):691-701. doi: 10.1177 ... The current case study applied patient-led integrated cognitive behavioural therapy in a 36-year-old male presenting with ...

  12. CBT for difficult-to-treat depression: single complex case

    Nevertheless, this case study is a good example of naturalistic practice-based evidence, with a high level of collaboration and participation from the service user. ... and this may be one of the reasons why treatment responses in chronic depression are superior for doses of 30 sessions or greater (Brewin et al., Reference Brewin, Reynolds and ...

  13. Single-Dose Psilocybin for a Treatment-Resistant Episode of Major

    Treatment-resistant depression is a challenging disorder to treat, as shown in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial. 1 Incidences of remission became ...

  14. Schema therapy for chronic depression: Results of a multiple single

    Background and objectives: The aim of this study was to test the effects of individual schema therapy (ST) for patients with chronic depression. Methods: Using a multiple-baseline single case series design, patients with chronic major depressive disorder (N = 25) first entered a 6-24 weeks baseline phase; this phase functioned as a no-treatment control condition.

  15. Comorbid Chronic Pain and Depression: Shared Risk Factors and

    Introduction. Depression is estimated to affect over 264 million people worldwide and is a leading cause of global disability ().Its clinical manifestations and outcomes are highly heterogeneous, with multiple factors underlying susceptibility, progression and treatment response ().One key factor that frequently complicates the diagnosis of depression is comorbid chronic pain, as patients ...

  16. Understanding the Link Between Chronic Disease and Depression

    This fact sheet provides information about the link between depression and chronic disease. It describes what a chronic disease is, symptoms of depression, and treatment options, and presents resources to find help for yourself or someone else. ... Clinical trials are research studies that look at ways to prevent, detect, or treat diseases and ...

  17. Oxidative Stress in Depression: A Case-control Study of Serum MDA

    The mean duration of illness in our study was approximately 4.5 years, which was similar to the study done by Hamed et al., 26 wherein the mean duration of depression was 6.3 years in cases, and as opposed to the study done by Alvarez Mon et al., 5 wherein the mean duration of illness was 16.12 ± 2.85 weeks. Our study found the mean HAM-D ...

  18. Age-related differences in the number of chronic diseases in

    Depression is the leading cause of the global burden of diseases [].The prevalence of depressive symptoms in middle-aged and older adults is 26.0%, and the prevalence rises with age [].Studies have revealed that depression may significantly predict cognitive decline and the development of chronic physical conditions [], which may be exaggerated by the increasing age as well [].

  19. A case of treatment-resistant depression in an older adult and a

    A case of treatment-resistant depression in an older adult and a discussion of treatment options. ... the sequenced treatment alternatives to relieve depression study ... Although there is increasing debate around the potential safety of the use of lithium in chronic kidney disease, 33 for Mr F it was felt that there were better initial ...

  20. Integrative medicine approaches to chronic depression: case studies of

    This retrospective case study focused on patients with chronic depression treated with a combination of modern Western medicine and CAM in May 2005-December 2011. When homeopathy is used for depression in patients who initially received conventional treatment, it is important to assess the progress of these patients after receiving homeopathy.

  21. Persistent Depressive Disorder (Dysthymia)

    Double depression refers to the onset of a major depressive episode when one already suffers from chronic depression. In this case, the persistent symptoms remain but an individual experiences ...

  22. Transcriptomic profiles in major depressive disorder: the role of

    Study design and sample characteristics. We analysed data from the multicentre, non-interventional, case-control BIOmarkers in DEPression (BIODEP) study.

  23. Integrative medicine approaches to chronic depression: case studies of

    This study suggests that integrative medicine can be a useful strategy for depression, including the use of a three-step strategy for reducing all dependence on clinical treatment. As most patients, especially chronic patients, significantly recovered from depression through homeopathy over 2 years, …

  24. Study: Specific Inflammatory Biomarkers Linked to Mental Health

    Researchers have suspected that there's a link between chronic low-grade inflammation and psychiatric disorders. Now, a recent cohort study points to specific inflammatory biomarkers that might be associated with an increased risk of depression, anxiety, and stress-related disorders.. The researchers evaluated longitudinal data from roughly 585 000 people in Sweden with no prior psychiatric ...

  25. Biological, Psychological, and Social Determinants of Depression: A

    Even in rodent studies, stress has a negative impact: chronic and unpredictable stress (and other forms of tension or stress) have been linked to unusual behaviour and depression symptoms . The depression process and related brain changes, however, have also been linked to the hyperactivity or dysregulation of the HPA axis [ 127 , 130 , 131 ...

  26. Study Finds Associations Between Chronic Pain and Anxiety, Depressive

    The studies and their populations were evaluated for the prevalence of anxiety and depression based on diagnosis and clinical cutoff scores, as well as differences in symptoms of anxiety and depression. 2. The total sample included 22,956 youth (mean age: 13.7 years [range: 4-24]) of which 12,614 had chronic pain and the majority of youths were ...

  27. Chronic sinus issues linked to anxiety and depression, study finds

    Chronic sinus issues linked to anxiety and depression, study finds Chronic and long-lasting sinus issues have been linked to anxiety and depression, an international study has found. September 13 ...

  28. Case management interventions in chronic disease reduce ...

    Among people with chronic health conditions, case management has beneficial effects on symptoms of depressive symptoms and symptoms of anxiety. Currently, research on case management interventions are rare. Future studies should assess the utility of case management for potentially preventative and …

  29. Chronic Pain-Induced Depression: A Review of Prevalence and Management

    Likewise, between 2019 and 2020, Alhalal et al. carried out a cross-sectional study in Saudi Arabia on 233 chronic pain patients to examine the impact of chronic pain on depression . They used the Chronic Pain Grade Scale to evaluate pain and the Center for Epidemiologic Studies-Depression scale to assess the patients' depressive symptoms.

  30. New study shows that chronic neurodegeneration can be prevented after

    University Hospitals and Case Western Reserve University research team reports a novel treatment after traumatic brain injury that prevents progression to chronic neurodegeneration Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are about 5 million people in the U.S. living with chronic neurodegeneration and related impairments due to TBI. In addition to ...